(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Lau BK et al. Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons. 2014 Br. J. Pharmacol. pmid:24460753
Xu P et al. Mosquito odorant receptor for DEET and methyl jasmonate. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25349401
Mirokuji Y et al. The JFFMA assessment of flavoring substances structurally related to menthol and uniquely used in Japan. 2014 Food Chem. Toxicol. pmid:24309148
Romero MC et al. Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model. 2014 Trop. Med. Int. Health pmid:25330410
Topp R et al. Topical menthol, ice, peripheral blood flow, and perceived discomfort. 2013 Mar-Apr J Athl Train pmid:23672386
Pereira EJ et al. The effect of inhaled menthol on upper airway resistance in humans: a randomized controlled crossover study. 2013 Jan-Feb Can. Respir. J. pmid:23457678
Topp R et al. The effect of either topical menthol or a placebo on functioning and knee pain among patients with knee OA. 2013 Apr-Jun J Geriatr Phys Ther pmid:22976810
Radu CD et al. Cotton-made cellulose support for anti-allergic pajamas. 2013 Carbohydr Polym pmid:23618296
Ngo-Thi MT et al. Enantioselective hydrolysis of dl-menthyl benzoate by cell-free extract of newly isolated Acinetobacter sp. ECU2040. 2013 Appl. Biochem. Biotechnol. pmid:23801098
Vahabi B et al. TRPM8 agonists modulate contraction of the pig urinary bladder. 2013 Can. J. Physiol. Pharmacol. pmid:23826977
Selescu T et al. Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. 2013 Chem. Senses pmid:23828908
Kurose M and Meng ID Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells. 2013 J. Neurophysiol. pmid:23636717
Plevkova J et al. The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol. 2013 J. Appl. Physiol. pmid:23640596
Villanti AC et al. Menthol cigarettes and mortality: keeping focus on the public health standard. 2013 Nicotine Tob. Res. pmid:22990220
Farco JA and Grundmann O Menthol--pharmacology of an important naturally medicinal "cool". 2013 Mini Rev Med Chem pmid:23061635
Rozza AL et al. Effect of menthol in experimentally induced ulcers: pathways of gastroprotection. 2013 Chem. Biol. Interact. pmid:24121185
Ostacolo C et al. Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists. 2013 Eur J Med Chem pmid:24095758
Vetter I et al. Amplified cold transduction in native nociceptors by M-channel inhibition. 2013 J. Neurosci. pmid:24133266
Ashoor A et al. Menthol inhibits 5-HT3 receptor-mediated currents. 2013 J. Pharmacol. Exp. Ther. pmid:23965380
Winhusen TM et al. A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. 2013 Drug Alcohol Depend pmid:24075226