MeSH term | MeSH ID | Detail |
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Acute Lung Injury | D055371 | 33 associated lipids |
(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.
To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Limonene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chen X et al. | Inhibition of farnesyl protein transferase and P21ras memebrane association by d-limonene in human pancreas tumor cells in vitro. | 1999 | Chin. Med. Sci. J. | pmid:12903812 |
End DW | Farnesyl protein transferase inhibitors and other therapies targeting the Ras signal transduction pathway. | 1999 | Invest New Drugs | pmid:10665477 |
Simándi B et al. | Supercritical carbon dioxide extraction and fractionation of fennel oil. | 1999 | J. Agric. Food Chem. | pmid:10564030 |
Roy A | Chemoenzymatic synthesis of homochiral (R)- and (S)-karahanaenol from (R)-limonene. | 1999 | J. Agric. Food Chem. | pmid:10606597 |
d-limonene. | 1999 | IARC Monogr Eval Carcinog Risks Hum | pmid:10804960 | |
Greene-McDowelle DM et al. | The effects of selected cotton-leaf volatiles on growth, development and aflatoxin production of Aspergillus parasiticus. | 1999 | Toxicon | pmid:10340828 |
Eummer JT et al. | Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors. | 1999 | Bioorg. Med. Chem. | pmid:10218815 |
Onken J and Berger RG | Effects of R-(+)-limonene on submerged cultures of the terpene transforming basidiomycete Pleurotus sapidus. | 1999 | J. Biotechnol. | pmid:10361724 |
Uedo N et al. | Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. | 1999 | Cancer Lett. | pmid:10374833 |
Duchamp-Viret P et al. | Odor response properties of rat olfactory receptor neurons. | 1999 | Science | pmid:10381881 |
van der Werf MJ et al. | Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. | 1999 | Appl. Environ. Microbiol. | pmid:10224006 |
Karlberg AT et al. | Regulatory classification of substances oxidized to skin sensitizers on exposure to air. | 1999 | Contact Derm. | pmid:10208503 |
Nilsson U et al. | Are contact allergens stable in patch test preparations? Investigation of the degradation of d-limonene hydroperoxides in petrolatum. | 1999 | Contact Derm. | pmid:10073439 |
Hardcastle IR et al. | Inhibition of protein prenylation by metabolites of limonene. | 1999 | Biochem. Pharmacol. | pmid:10075086 |
Barnhart ET et al. | Evaluation of potential disinfectants for preslaughter broiler crop decontamination. | 1999 | Poult. Sci. | pmid:10023743 |
Crowell PL | Prevention and therapy of cancer by dietary monoterpenes. | 1999 | J. Nutr. | pmid:10082788 |
Donaldson MJ et al. | XR3054, structurally related to limonene, is a novel inhibitor of farnesyl protein transferase. | 1999 | Eur. J. Cancer | pmid:10533487 |
Oshiro Y et al. | Exploration of the transformation potential of a unique male rat protein alpha2u-globulin using hamster embryonic cells. | 1998 May-Jun | Toxicol Pathol | pmid:9608644 |
Morse MA | Inhibition of NNK-induced lung tumorigenesis by modulators of NNK activation. | 1998 Jul-Aug | Exp. Lung Res. | pmid:9659585 |
Diez I et al. | Influence of d-limonene on the transdermal penetration of felodipine. | 1998 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:9625266 |
Zhao K and Singh J | Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone. | 1998 | J Control Release | pmid:9795076 |
Chen H et al. | Pharmacokinetics of d-limonene in the rat by GC-MS assay. | 1998 | J Pharm Biomed Anal | pmid:9682146 |
Estell RE et al. | Effects of volatile compounds on consumption of alfalfa pellets by sheep. | 1998 | J. Anim. Sci. | pmid:9464903 |
van Lieshout EM et al. | Effects of the sulforaphane analog compound 30, indole-3-carbinol, D-limonene or relafen on glutathione S-transferases and glutathione peroxidase of the rat digestive tract. | 1998 | Biochim. Biophys. Acta | pmid:9545594 |
Lehman-McKeeman LD et al. | 2-sec-butyl-4,5-dihydrothiazole is a ligand for mouse urinary protein and rat alpha 2u-globulin: physiological and toxicological relevance. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9512724 |
Wakelin SH et al. | Allergic contact dermatitis from d-limonene in a laboratory technician. | 1998 | Contact Derm. | pmid:9536411 |
Kaur M et al. | Receptor-Ck-dependent regulation of genes involved in the cell cycle. | 1998 | Mol. Cell. Biochem. | pmid:9562250 |
PrÃborský J et al. | Percutaneous absorption of disopyramide, lidocaine and trimecaine. | 1998 | Acta Univ Palacki Olomuc Fac Med | pmid:9684478 |
Vigushin DM et al. | Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee. | 1998 | Cancer Chemother. Pharmacol. | pmid:9654110 |
Savithiry N et al. | Degradation of pinene by Bacillus pallidus BR425. | 1998 | Biodegradation | pmid:10192895 |
Bardon S et al. | Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines. | 1998 | Nutr Cancer | pmid:9824849 |
Zhang T et al. | [Influence of fry-processing on outward character and inner quality of volatile oil containing drugs such as fructus Viticis, etc]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:11243151 |
Chen X et al. | [Effect of d-limonene, Salvia miltiorrhiza and turmeric derivatives on membrane association of Ras gene product and gap junction intercellular communication]. | 1998 | Yao Xue Xue Bao | pmid:12016941 |
Crowell PL | Monoterpenes in breast cancer chemoprevention. | 1997 Nov-Dec | Breast Cancer Res. Treat. | pmid:9478274 |
Chen X et al. | Inhibition of farnesyl protein transferase by monoterpene, curcumin derivatives and gallotannin. | 1997 Jul-Aug | Anticancer Res. | pmid:9252680 |
Devlieghere F et al. | Evaluation, modelling and optimization of the cleaning process of contaminated plastic food refillables. | 1997 Aug-Oct | Food Addit Contam | pmid:9373531 |
Chang YC et al. | Allergic contact dermatitis from oxidized d-limonene. | 1997 | Contact Derm. | pmid:9455646 |
Galli I et al. | DNA replication and order of cell cycle events: a role for protein isoprenylation? | 1997 | Biol. Chem. | pmid:9348105 |
Savithiry N et al. | Production of alpha-terpineol from Escherichia coli cells expressing thermostable limonene hydratase. | 1997 | Appl. Biochem. Biotechnol. | pmid:9170246 |
Nakaizumi A et al. | d-Limonene inhibits N-nitrosobis(2-oxopropyl)amine induced hamster pancreatic carcinogenesis. | 1997 | Cancer Lett. | pmid:9233838 |
Kreuzer J et al. | Protein kinase C activation after cellular adhesion on fibronectin: partial suppression after inhibition of protein isoprenylation. | 1997 | Eur. J. Med. Res. | pmid:9233906 |
Gilbert ES and Crowley DE | Plant compounds that induce polychlorinated biphenyl biodegradation by Arthrobacter sp. strain B1B. | 1997 | Appl. Environ. Microbiol. | pmid:9143124 |
Miller AC and Samid D | Tumor radiosensitization based on the use of inhibitors of the mevalonate pathway of cholesterol synthesis. | 1997 | Adv. Exp. Med. Biol. | pmid:9547635 |
Lewis KA and Hohl RJ | Modulation of RAS expression in human malignant cells by dietary supplements. | 1997 | Nutrition | pmid:9357036 |
Poet TS and Borghoff SJ | In vitro uptake of methyl tert-butyl ether in male rat kidney: use of a two-compartment model to describe protein interactions. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9266807 |
Karlberg AT and Dooms-Goossens A | Contact allergy to oxidized d-limonene among dermatitis patients. | 1997 | Contact Derm. | pmid:9165203 |
Youngentob SL et al. | Odorant threshold following methyl bromide-induced lesions of the olfactory epithelium. | 1997 | Physiol. Behav. | pmid:9383109 |
Kunta JR et al. | Effect of menthol and related terpenes on the percutaneous absorption of propranolol across excised hairless mouse skin. | 1997 | J Pharm Sci | pmid:9423148 |
el-Bayoumy K et al. | Effects of 1,4-phenylenebis(methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. | 1996 Sep-Oct | Anticancer Res. | pmid:8917375 |
Jonker D et al. | Toxicity of mixtures of nephrotoxicants with similar or dissimilar mode of action. | 1996 Nov-Dec | Food Chem. Toxicol. | pmid:9119318 |
Adam KP et al. | Partial purification and characterization of a monoterpene cyclase, limonene synthase, from the liverwort Ricciocarpos natans. | 1996 | Arch. Biochem. Biophys. | pmid:8806745 |
Karlson J et al. | Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action. | 1996 | Anticancer Drugs | pmid:8826611 |
O'Shaughnessy JA | Chemoprevention of breast cancer. | 1996 | JAMA | pmid:8614122 |
Alvares K et al. | Ciprofibrate represses alpha 2u-globulin expression in liver and inhibits d-limonene nephrotoxicity. | 1996 | Carcinogenesis | pmid:8625456 |
Jansen LA and Jongen WM | The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication. | 1996 | Carcinogenesis | pmid:8625460 |
Kawamori T et al. | Inhibitory effects of d-limonene on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats. | 1996 | Carcinogenesis | pmid:8625465 |
Kimura J et al. | Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model. | 1996 | Jpn. J. Cancer Res. | pmid:8766522 |
Poon GK et al. | Identification and characterization of limonene metabolites in patients with advanced cancer by liquid chromatography/mass spectrometry. | 1996 | Drug Metab. Dispos. | pmid:8723738 |
Williams GM and Whysner J | Epigenetic carcinogens: evaluation and risk assessment. | 1996 | Exp. Toxicol. Pathol. | pmid:8672874 |
Morse MA and Toburen AL | Inhibition of metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by limonene. | 1996 | Cancer Lett. | pmid:8665490 |
Saito K et al. | Alpha 2u-globulins in the urine of male rats: a reliable indicator for alpha 2u-globulin accumulation in the kidney. | 1996 | Toxicology | pmid:8571386 |
Pöhle H and Kliche R | [Emission of odors from composting of biological waste]. | 1996 | Zentralbl Hyg Umweltmed | pmid:9409908 |
Broitman SA et al. | Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo. | 1996 | Adv. Exp. Med. Biol. | pmid:8886130 |
Crowell PL et al. | Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer. | 1996 | Adv. Exp. Med. Biol. | pmid:8886131 |
Misra G et al. | Aerobic biodegradation of selected monoterpenes. | 1996 | Appl. Microbiol. Biotechnol. | pmid:8987470 |
Ariazi EA and Gould MN | Identifying differential gene expression in monoterpene-treated mammary carcinomas using subtractive display. | 1996 | J. Biol. Chem. | pmid:8910589 |
Whysner J and Williams GM | d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. | 1996 | Pharmacol. Ther. | pmid:8910952 |
Huang J et al. | [GC-MS analysis of essential oils from the pericarps of Illicium majus Hook.f.et. Thoms. and I. micranthum Dunn]. | 1996 | Zhongguo Zhong Yao Za Zhi | pmid:9812698 |
Huang J et al. | [GC-MS analysis of essential oils from pericarps of Illicium brevistylum A. C. Smith and I. jiadifengpi B.N. Chang]. | 1996 | Zhongguo Zhong Yao Za Zhi | pmid:9772632 |
Von Burg R | Limonene. | 1995 Nov-Dec | J Appl Toxicol | pmid:8603937 |
Touvay C et al. | Effect of limonene and sobrerol on monocrotaline-induced lung alterations and pulmonary hypertension. | 1995 May-Jun | Int. Arch. Allergy Immunol. | pmid:7542078 |
Whalen JD et al. | Xylene substitutes in frozen sections. | 1995 | Dermatol Surg | pmid:7712095 |
York M et al. | Skin irritation testing in man for hazard assessment--evaluation of four patch systems. | 1995 | Hum Exp Toxicol | pmid:8579884 |
Scheuplein RJ | The use of biological data in addition to the carcinogen bioassay in quantitative risk assessment. | 1995 | Prog. Clin. Biol. Res. | pmid:8532727 |
Williams GM and Whysner J | Mechanistic considerations in risk assessment for epigenetic tumor-promoting carcinogens. | 1995 | Prog. Clin. Biol. Res. | pmid:8532729 |
Gould MN | Prevention and therapy of mammary cancer by monoterpenes. | 1995 | J. Cell. Biochem. Suppl. | pmid:8538191 |
Luján HD et al. | Isoprenylation of proteins in the protozoan Giardia lamblia. | 1995 | Mol. Biochem. Parasitol. | pmid:8538683 |
Martins C et al. | Allergic contact dermatitis from dipentene in wax polish. | 1995 | Contact Derm. | pmid:8549131 |
Hursting SD et al. | Chemoprevention of spontaneous tumorigenesis in p53-knockout mice. | 1995 | Cancer Res. | pmid:7664260 |
Hohl RJ and Lewis K | Differential effects of monoterpenes and lovastatin on RAS processing. | 1995 | J. Biol. Chem. | pmid:7615555 |
Rosenbaum MR and Kerlin RL | Erythema multiforme major and disseminated intravascular coagulation in a dog following application of a d-limonene-based insecticidal dip. | 1995 | J. Am. Vet. Med. Assoc. | pmid:7591926 |
Ohara N et al. | Combined effect of d-limonene pretreatment and temperature on the rat skin permeation of lipophilic and hydrophilic drugs. | 1995 | Biol. Pharm. Bull. | pmid:7550099 |
Yamane MA et al. | Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action. | 1995 | J. Pharm. Pharmacol. | pmid:8932680 |
Gelb MH et al. | The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol. | 1995 | Cancer Lett. | pmid:7767906 |
Miyazaki S et al. | Percutaneous absorption of indomethacin from pluronic F127 gels in rats. | 1995 | J. Pharm. Pharmacol. | pmid:7674126 |
Kristiansen E and Madsen C | Induction of protein droplet (alpha 2 mu-globulin) nephropathy in male rats after short-term dosage with 1,8-cineole and l-limonene. | 1995 | Toxicol. Lett. | pmid:7482582 |
Kurahashi T et al. | Suppression of odorant responses by odorants in olfactory receptor cells. | 1994 | Science | pmid:8016645 |
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Gould MN et al. | Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras. | 1994 | Cancer Res. | pmid:8012978 |
Larsen MC et al. | The induction of five rat hepatic P450 cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific. | 1994 | Arch. Biochem. Biophys. | pmid:7979401 |
Chander SK et al. | Effectiveness of combined limonene and 4-hydroxyandrostenedione in the treatment of NMU-induced rat mammary tumours. | 1994 | Br. J. Cancer | pmid:8180018 |
Haag JD and Gould MN | Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene. | 1994 | Cancer Chemother. Pharmacol. | pmid:7923558 |
Friedman MI et al. | Limonene in expired lung air of patients with liver disease. | 1994 | Dig. Dis. Sci. | pmid:8050315 |
Hard GC and Whysner J | Risk assessment of d-limonene: an example of male rat-specific renal tumorigens. | 1994 | Crit. Rev. Toxicol. | pmid:7945892 |
Lehman-McKeeman LD and Caudill D | d-Limonene induced hyaline droplet nephropathy in alpha 2u-globulin transgenic mice. | 1994 | Fundam Appl Toxicol | pmid:7532604 |
Cornwell PA et al. | Wide-angle X-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment. | 1994 | J. Pharm. Pharmacol. | pmid:7536240 |
Crowell PL et al. | Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation. | 1994 | Biochem. Pharmacol. | pmid:8185648 |
Meding B et al. | Hand eczema in car mechanics. | 1994 | Contact Derm. | pmid:8187510 |
Sybilska D et al. | Chromatographic studies of the enantiomeric composition of some therapeutic compositions applied in the treatment of liver and kidney diseases. | 1994 | J Chromatogr A | pmid:8205230 |
Karlberg AT et al. | Influence of an anti-oxidant on the formation of allergenic compounds during auto-oxidation of d-limonene. | 1994 | Ann Occup Hyg | pmid:8210084 |