(-)-Limonene

(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.

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Introduction

To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Limonene

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

What pathways are associated with (-)-Limonene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Limonene?

Related references are published most in these journals:

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What functions are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What lipids are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Limonene

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Authors Title Published Journal PubMed Link
Chen X et al. Inhibition of farnesyl protein transferase and P21ras memebrane association by d-limonene in human pancreas tumor cells in vitro. 1999 Chin. Med. Sci. J. pmid:12903812
End DW Farnesyl protein transferase inhibitors and other therapies targeting the Ras signal transduction pathway. 1999 Invest New Drugs pmid:10665477
Simándi B et al. Supercritical carbon dioxide extraction and fractionation of fennel oil. 1999 J. Agric. Food Chem. pmid:10564030
Roy A Chemoenzymatic synthesis of homochiral (R)- and (S)-karahanaenol from (R)-limonene. 1999 J. Agric. Food Chem. pmid:10606597
d-limonene. 1999 IARC Monogr Eval Carcinog Risks Hum pmid:10804960
Greene-McDowelle DM et al. The effects of selected cotton-leaf volatiles on growth, development and aflatoxin production of Aspergillus parasiticus. 1999 Toxicon pmid:10340828
Eummer JT et al. Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors. 1999 Bioorg. Med. Chem. pmid:10218815
Onken J and Berger RG Effects of R-(+)-limonene on submerged cultures of the terpene transforming basidiomycete Pleurotus sapidus. 1999 J. Biotechnol. pmid:10361724
Uedo N et al. Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. 1999 Cancer Lett. pmid:10374833
Duchamp-Viret P et al. Odor response properties of rat olfactory receptor neurons. 1999 Science pmid:10381881
van der Werf MJ et al. Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. 1999 Appl. Environ. Microbiol. pmid:10224006
Karlberg AT et al. Regulatory classification of substances oxidized to skin sensitizers on exposure to air. 1999 Contact Derm. pmid:10208503
Nilsson U et al. Are contact allergens stable in patch test preparations? Investigation of the degradation of d-limonene hydroperoxides in petrolatum. 1999 Contact Derm. pmid:10073439
Hardcastle IR et al. Inhibition of protein prenylation by metabolites of limonene. 1999 Biochem. Pharmacol. pmid:10075086
Barnhart ET et al. Evaluation of potential disinfectants for preslaughter broiler crop decontamination. 1999 Poult. Sci. pmid:10023743
Crowell PL Prevention and therapy of cancer by dietary monoterpenes. 1999 J. Nutr. pmid:10082788
Donaldson MJ et al. XR3054, structurally related to limonene, is a novel inhibitor of farnesyl protein transferase. 1999 Eur. J. Cancer pmid:10533487
Oshiro Y et al. Exploration of the transformation potential of a unique male rat protein alpha2u-globulin using hamster embryonic cells. 1998 May-Jun Toxicol Pathol pmid:9608644
Morse MA Inhibition of NNK-induced lung tumorigenesis by modulators of NNK activation. 1998 Jul-Aug Exp. Lung Res. pmid:9659585
Diez I et al. Influence of d-limonene on the transdermal penetration of felodipine. 1998 Jan-Mar Eur J Drug Metab Pharmacokinet pmid:9625266
Zhao K and Singh J Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone. 1998 J Control Release pmid:9795076
Chen H et al. Pharmacokinetics of d-limonene in the rat by GC-MS assay. 1998 J Pharm Biomed Anal pmid:9682146
Estell RE et al. Effects of volatile compounds on consumption of alfalfa pellets by sheep. 1998 J. Anim. Sci. pmid:9464903
van Lieshout EM et al. Effects of the sulforaphane analog compound 30, indole-3-carbinol, D-limonene or relafen on glutathione S-transferases and glutathione peroxidase of the rat digestive tract. 1998 Biochim. Biophys. Acta pmid:9545594
Lehman-McKeeman LD et al. 2-sec-butyl-4,5-dihydrothiazole is a ligand for mouse urinary protein and rat alpha 2u-globulin: physiological and toxicological relevance. 1998 Toxicol. Appl. Pharmacol. pmid:9512724
Wakelin SH et al. Allergic contact dermatitis from d-limonene in a laboratory technician. 1998 Contact Derm. pmid:9536411
Kaur M et al. Receptor-Ck-dependent regulation of genes involved in the cell cycle. 1998 Mol. Cell. Biochem. pmid:9562250
Príborský J et al. Percutaneous absorption of disopyramide, lidocaine and trimecaine. 1998 Acta Univ Palacki Olomuc Fac Med pmid:9684478
Vigushin DM et al. Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee. 1998 Cancer Chemother. Pharmacol. pmid:9654110
Savithiry N et al. Degradation of pinene by Bacillus pallidus BR425. 1998 Biodegradation pmid:10192895
Bardon S et al. Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines. 1998 Nutr Cancer pmid:9824849
Zhang T et al. [Influence of fry-processing on outward character and inner quality of volatile oil containing drugs such as fructus Viticis, etc]. 1998 Zhongguo Zhong Yao Za Zhi pmid:11243151
Chen X et al. [Effect of d-limonene, Salvia miltiorrhiza and turmeric derivatives on membrane association of Ras gene product and gap junction intercellular communication]. 1998 Yao Xue Xue Bao pmid:12016941
Crowell PL Monoterpenes in breast cancer chemoprevention. 1997 Nov-Dec Breast Cancer Res. Treat. pmid:9478274
Chen X et al. Inhibition of farnesyl protein transferase by monoterpene, curcumin derivatives and gallotannin. 1997 Jul-Aug Anticancer Res. pmid:9252680
Devlieghere F et al. Evaluation, modelling and optimization of the cleaning process of contaminated plastic food refillables. 1997 Aug-Oct Food Addit Contam pmid:9373531
Chang YC et al. Allergic contact dermatitis from oxidized d-limonene. 1997 Contact Derm. pmid:9455646
Galli I et al. DNA replication and order of cell cycle events: a role for protein isoprenylation? 1997 Biol. Chem. pmid:9348105
Savithiry N et al. Production of alpha-terpineol from Escherichia coli cells expressing thermostable limonene hydratase. 1997 Appl. Biochem. Biotechnol. pmid:9170246
Nakaizumi A et al. d-Limonene inhibits N-nitrosobis(2-oxopropyl)amine induced hamster pancreatic carcinogenesis. 1997 Cancer Lett. pmid:9233838
Kreuzer J et al. Protein kinase C activation after cellular adhesion on fibronectin: partial suppression after inhibition of protein isoprenylation. 1997 Eur. J. Med. Res. pmid:9233906
Gilbert ES and Crowley DE Plant compounds that induce polychlorinated biphenyl biodegradation by Arthrobacter sp. strain B1B. 1997 Appl. Environ. Microbiol. pmid:9143124
Miller AC and Samid D Tumor radiosensitization based on the use of inhibitors of the mevalonate pathway of cholesterol synthesis. 1997 Adv. Exp. Med. Biol. pmid:9547635
Lewis KA and Hohl RJ Modulation of RAS expression in human malignant cells by dietary supplements. 1997 Nutrition pmid:9357036
Poet TS and Borghoff SJ In vitro uptake of methyl tert-butyl ether in male rat kidney: use of a two-compartment model to describe protein interactions. 1997 Toxicol. Appl. Pharmacol. pmid:9266807
Karlberg AT and Dooms-Goossens A Contact allergy to oxidized d-limonene among dermatitis patients. 1997 Contact Derm. pmid:9165203
Youngentob SL et al. Odorant threshold following methyl bromide-induced lesions of the olfactory epithelium. 1997 Physiol. Behav. pmid:9383109
Kunta JR et al. Effect of menthol and related terpenes on the percutaneous absorption of propranolol across excised hairless mouse skin. 1997 J Pharm Sci pmid:9423148
el-Bayoumy K et al. Effects of 1,4-phenylenebis(methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. 1996 Sep-Oct Anticancer Res. pmid:8917375
Jonker D et al. Toxicity of mixtures of nephrotoxicants with similar or dissimilar mode of action. 1996 Nov-Dec Food Chem. Toxicol. pmid:9119318
Adam KP et al. Partial purification and characterization of a monoterpene cyclase, limonene synthase, from the liverwort Ricciocarpos natans. 1996 Arch. Biochem. Biophys. pmid:8806745
Karlson J et al. Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action. 1996 Anticancer Drugs pmid:8826611
O'Shaughnessy JA Chemoprevention of breast cancer. 1996 JAMA pmid:8614122
Alvares K et al. Ciprofibrate represses alpha 2u-globulin expression in liver and inhibits d-limonene nephrotoxicity. 1996 Carcinogenesis pmid:8625456
Jansen LA and Jongen WM The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication. 1996 Carcinogenesis pmid:8625460
Kawamori T et al. Inhibitory effects of d-limonene on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats. 1996 Carcinogenesis pmid:8625465
Kimura J et al. Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model. 1996 Jpn. J. Cancer Res. pmid:8766522
Poon GK et al. Identification and characterization of limonene metabolites in patients with advanced cancer by liquid chromatography/mass spectrometry. 1996 Drug Metab. Dispos. pmid:8723738
Williams GM and Whysner J Epigenetic carcinogens: evaluation and risk assessment. 1996 Exp. Toxicol. Pathol. pmid:8672874
Morse MA and Toburen AL Inhibition of metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by limonene. 1996 Cancer Lett. pmid:8665490
Saito K et al. Alpha 2u-globulins in the urine of male rats: a reliable indicator for alpha 2u-globulin accumulation in the kidney. 1996 Toxicology pmid:8571386
Pöhle H and Kliche R [Emission of odors from composting of biological waste]. 1996 Zentralbl Hyg Umweltmed pmid:9409908
Broitman SA et al. Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo. 1996 Adv. Exp. Med. Biol. pmid:8886130
Crowell PL et al. Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer. 1996 Adv. Exp. Med. Biol. pmid:8886131
Misra G et al. Aerobic biodegradation of selected monoterpenes. 1996 Appl. Microbiol. Biotechnol. pmid:8987470
Ariazi EA and Gould MN Identifying differential gene expression in monoterpene-treated mammary carcinomas using subtractive display. 1996 J. Biol. Chem. pmid:8910589
Whysner J and Williams GM d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. 1996 Pharmacol. Ther. pmid:8910952
Huang J et al. [GC-MS analysis of essential oils from the pericarps of Illicium majus Hook.f.et. Thoms. and I. micranthum Dunn]. 1996 Zhongguo Zhong Yao Za Zhi pmid:9812698
Huang J et al. [GC-MS analysis of essential oils from pericarps of Illicium brevistylum A. C. Smith and I. jiadifengpi B.N. Chang]. 1996 Zhongguo Zhong Yao Za Zhi pmid:9772632
Von Burg R Limonene. 1995 Nov-Dec J Appl Toxicol pmid:8603937
Touvay C et al. Effect of limonene and sobrerol on monocrotaline-induced lung alterations and pulmonary hypertension. 1995 May-Jun Int. Arch. Allergy Immunol. pmid:7542078
Whalen JD et al. Xylene substitutes in frozen sections. 1995 Dermatol Surg pmid:7712095
York M et al. Skin irritation testing in man for hazard assessment--evaluation of four patch systems. 1995 Hum Exp Toxicol pmid:8579884
Scheuplein RJ The use of biological data in addition to the carcinogen bioassay in quantitative risk assessment. 1995 Prog. Clin. Biol. Res. pmid:8532727
Williams GM and Whysner J Mechanistic considerations in risk assessment for epigenetic tumor-promoting carcinogens. 1995 Prog. Clin. Biol. Res. pmid:8532729
Gould MN Prevention and therapy of mammary cancer by monoterpenes. 1995 J. Cell. Biochem. Suppl. pmid:8538191
Luján HD et al. Isoprenylation of proteins in the protozoan Giardia lamblia. 1995 Mol. Biochem. Parasitol. pmid:8538683
Martins C et al. Allergic contact dermatitis from dipentene in wax polish. 1995 Contact Derm. pmid:8549131
Hursting SD et al. Chemoprevention of spontaneous tumorigenesis in p53-knockout mice. 1995 Cancer Res. pmid:7664260
Hohl RJ and Lewis K Differential effects of monoterpenes and lovastatin on RAS processing. 1995 J. Biol. Chem. pmid:7615555
Rosenbaum MR and Kerlin RL Erythema multiforme major and disseminated intravascular coagulation in a dog following application of a d-limonene-based insecticidal dip. 1995 J. Am. Vet. Med. Assoc. pmid:7591926
Ohara N et al. Combined effect of d-limonene pretreatment and temperature on the rat skin permeation of lipophilic and hydrophilic drugs. 1995 Biol. Pharm. Bull. pmid:7550099
Yamane MA et al. Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action. 1995 J. Pharm. Pharmacol. pmid:8932680
Gelb MH et al. The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol. 1995 Cancer Lett. pmid:7767906
Miyazaki S et al. Percutaneous absorption of indomethacin from pluronic F127 gels in rats. 1995 J. Pharm. Pharmacol. pmid:7674126
Kristiansen E and Madsen C Induction of protein droplet (alpha 2 mu-globulin) nephropathy in male rats after short-term dosage with 1,8-cineole and l-limonene. 1995 Toxicol. Lett. pmid:7482582
Kurahashi T et al. Suppression of odorant responses by odorants in olfactory receptor cells. 1994 Science pmid:8016645
Wang YY and Wang H [Analysis of chemical constituents of essential oil from dechengqi decoction]. 1994 Zhongguo Zhong Yao Za Zhi pmid:8011141
Gould MN et al. Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras. 1994 Cancer Res. pmid:8012978
Larsen MC et al. The induction of five rat hepatic P450 cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific. 1994 Arch. Biochem. Biophys. pmid:7979401
Chander SK et al. Effectiveness of combined limonene and 4-hydroxyandrostenedione in the treatment of NMU-induced rat mammary tumours. 1994 Br. J. Cancer pmid:8180018
Haag JD and Gould MN Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene. 1994 Cancer Chemother. Pharmacol. pmid:7923558
Friedman MI et al. Limonene in expired lung air of patients with liver disease. 1994 Dig. Dis. Sci. pmid:8050315
Hard GC and Whysner J Risk assessment of d-limonene: an example of male rat-specific renal tumorigens. 1994 Crit. Rev. Toxicol. pmid:7945892
Lehman-McKeeman LD and Caudill D d-Limonene induced hyaline droplet nephropathy in alpha 2u-globulin transgenic mice. 1994 Fundam Appl Toxicol pmid:7532604
Cornwell PA et al. Wide-angle X-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment. 1994 J. Pharm. Pharmacol. pmid:7536240
Crowell PL et al. Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation. 1994 Biochem. Pharmacol. pmid:8185648
Meding B et al. Hand eczema in car mechanics. 1994 Contact Derm. pmid:8187510
Sybilska D et al. Chromatographic studies of the enantiomeric composition of some therapeutic compositions applied in the treatment of liver and kidney diseases. 1994 J Chromatogr A pmid:8205230
Karlberg AT et al. Influence of an anti-oxidant on the formation of allergenic compounds during auto-oxidation of d-limonene. 1994 Ann Occup Hyg pmid:8210084