(-)-Limonene

(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.

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Introduction

To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Limonene

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

What pathways are associated with (-)-Limonene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Limonene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What lipids are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Limonene

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Authors Title Published Journal PubMed Link
Mahmoud SS et al. Cosuppression of limonene-3-hydroxylase in peppermint promotes accumulation of limonene in the essential oil. 2004 Phytochemistry pmid:15003417
Maffei M et al. Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential. 2001 Phytochemistry pmid:11672734
Zhao T et al. The influence of Ceratocystis polonica inoculation and methyl jasmonate application on terpene chemistry of Norway spruce, Picea abies. 2010 Phytochemistry pmid:20557909
Demyttenaere JC et al. Biotransformation of (R)-(+)- and (S)-(-)-limonene by fungi and the use of solid phase microextraction for screening. 2001 Phytochemistry pmid:11382235
Carter OA et al. Monoterpene biosynthesis pathway construction in Escherichia coli. 2003 Phytochemistry pmid:12943759
Tankeu S et al. Vibrational spectroscopy as a rapid quality control method for Melaleuca alternifolia cheel (tea tree oil). 2014 Jan-Feb Phytochem Anal pmid:23934710
Moradi M et al. Comparison of headspace solid-phase microextraction, headspace single-drop microextraction and hydrodistillation for chemical screening of volatiles in Myrtus communis L. 2012 Jul-Aug Phytochem Anal pmid:22069217
Laing DG et al. Odor masking in the rat. 1989 Physiol. Behav. pmid:2780835
Youngentob SL et al. Odorant threshold following methyl bromide-induced lesions of the olfactory epithelium. 1997 Physiol. Behav. pmid:9383109
Belkin MA et al. Sum-frequency vibrational spectroscopy on chiral liquids: a novel technique to probe molecular chirality. 2000 Phys. Rev. Lett. pmid:11082574
Walser ML et al. High-resolution mass spectrometric analysis of secondary organic aerosol produced by ozonation of limonene. 2008 Phys Chem Chem Phys pmid:18259641
Bateman AP et al. Photolytic processing of secondary organic aerosols dissolved in cloud droplets. 2011 Phys Chem Chem Phys pmid:21617794
Maksymiuk CS et al. Secondary organic aerosol formation from multiphase oxidation of limonene by ozone: mechanistic constraints via two-dimensional heteronuclear NMR spectroscopy. 2009 Phys Chem Chem Phys pmid:19727487
Bateman AP et al. Time-resolved molecular characterization of limonene/ozone aerosol using high-resolution electrospray ionization mass spectrometry. 2009 Phys Chem Chem Phys pmid:19727500
Śmiałek MA et al. Limonene: electronic state spectroscopy by high-resolution vacuum ultraviolet photoabsorption, electron scattering, He(I) photoelectron spectroscopy and ab initio calculations. 2012 Phys Chem Chem Phys pmid:22231475
Souza MC et al. Evaluation of anti-inflammatory activity of essential oils from two Asteraceae species. 2003 Pharmazie pmid:12967039
Krishnaiah YS et al. Effect of limonene on the in vitro permeation of nicardipine hydrochloride across the excised rat abdominal skin. 2002 Pharmazie pmid:12561249
Krishnaiah YS et al. In vitro percutaneous permeability enhancement of nimodipine by limonene across the excised rat abdominal skin. 2004 Pharmazie pmid:15638083
Liu T et al. Bioequivalence evaluation of two D-limonene capsule formulations in healthy Chinese volunteers. 2008 Pharmazie pmid:18972832
Bell GD Cholelitholytic agents. 1983 Pharmacol. Ther. pmid:6419241
Whysner J and Williams GM d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. 1996 Pharmacol. Ther. pmid:8910952
Si A et al. Effects of NMDA receptor antagonists on olfactory learning and memory in the honeybee (Apis mellifera). 2004 Pharmacol. Biochem. Behav. pmid:14751445
Lima NG et al. Anxiolytic-like activity and GC-MS analysis of (R)-(+)-limonene fragrance, a natural compound found in foods and plants. 2013 Pharmacol. Biochem. Behav. pmid:22995322
Koyama Y et al. Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model. 1994 Pharm. Res. pmid:8008702
Rastogi SK and Singh J Iontophoretic enhancement of leuprolide acetate by fatty acids, limonene, and depilatory lotions through porcine epidermis. 2004 Pharm Dev Technol pmid:15581070
Zhang CF et al. Effects of enantiomer and isomer permeation enhancers on transdermal delivery of ligustrazine hydrochloride. 2006 Pharm Dev Technol pmid:17101512
Krishnaiah YS et al. Studies on optimizing in vitro transdermal permeation of ondansetron hydrochloride using nerodilol, carvone, and limonene as penetration enhancers. 2008 Pharm Dev Technol pmid:18484486
Rastogi SK and Singh J Effect of chemical penetration enhancer and iontophoresis on the in vitro percutaneous absorption enhancement of insulin through porcine epidermis. 2005 Pharm Dev Technol pmid:15776817
Erdal MS et al. Impacts of chemical enhancers on skin permeation and deposition of terbinafine. 2014 Pharm Dev Technol pmid:23841559
Kostyukovsky M et al. Activation of octopaminergic receptors by essential oil constituents isolated from aromatic plants: possible mode of action against insect pests. 2002 Pest Manag. Sci. pmid:12449528
Miresmailli S et al. Comparative toxicity of Rosmarinus officinalis L. essential oil and blends of its major constituents against Tetranychus urticae Koch (Acari: Tetranychidae) on two different host plants. 2006 Pest Manag. Sci. pmid:16470541
Cheng SS et al. Insecticidal activities of leaf and twig essential oils from Clausena excavata against Aedes aegypti and Aedes albopictus larvae. 2009 Pest Manag. Sci. pmid:19115256
López S et al. Electrophysiological and behavioural responses of Pityophthorus pubescens (Coleoptera: Scolytinae) to (E,E)-α-farnesene, (R)-(+)-limonene and (S)-(-)-verbenone in Pinus radiata (Pinaceae) stands in northern Spain. 2013 Pest Manag. Sci. pmid:22764125
Gannu R et al. In vitro permeation of carvedilol through porcine skin: effect of vehicles and penetration enhancers. 2008 Jul-Aug PDA J Pharm Sci Technol pmid:19174954
Govindarajan M et al. Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species. 2012 Parasitol. Res. pmid:22139403
Bai J et al. Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway. 2016 Oxid Med Cell Longev pmid:26682012
Wender PA and Zhang L Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes. 2000 Org. Lett. pmid:10930274
Pitsinos EN et al. Enantioselective total synthesis of (-)-laurenditerpenol. 2012 Org. Lett. pmid:22905649
Wender PA et al. Asymmetric synthesis of the tricyclic core of NGF-inducing cyathane diterpenes via a transition-metal-catalyzed [5 + 2] cycloaddition. 2001 Org. Lett. pmid:11418060
Vajrabhaya LO et al. Cytotoxicity evaluation of gutta-percha solvents: Chloroform and GP-Solvent (limonene). 2004 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:15583552
Giri RK et al. d-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc. 1999 Sep-Oct Oncol. Rep. pmid:10425313
Jia SS et al. Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells. 2013 Oncol. Rep. pmid:23117412
D'Erme AM et al. Contact dermatitis due to dipentene and pine oil in an automobile mechanic. 2012 Occup Environ Med pmid:22146991
Tammaro A et al. Archer dermatitis: a new case of allergic contact dermatitis. 2013 Occup Environ Med pmid:23873984
Lewis KA and Hohl RJ Modulation of RAS expression in human malignant cells by dietary supplements. 1997 Nutrition pmid:9357036
d-limonene, an anticarcinogenic terpene. 1988 Nutr. Rev. pmid:3067145
Fukumoto S et al. Flavor components of monoterpenes in citrus essential oils enhance the release of monoamines from rat brain slices. 2006 Feb-Apr Nutr Neurosci pmid:16913049
Zhou W et al. Components of lemon essential oil attenuate dementia induced by scopolamine. 2009 Nutr Neurosci pmid:19356307
Bardon S et al. Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines. 1998 Nutr Cancer pmid:9824849
Miller JA et al. Adipose tissue accumulation of d-limonene with the consumption of a lemonade preparation rich in d-limonene content. 2010 Nutr Cancer pmid:20661827