(-)-Perillyl alcohol

(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Perillyl alcohol?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol

MeSH term MeSH ID Detail
Lymphoma, Mantle-Cell D020522 5 associated lipids
Brain Neoplasms D001932 15 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Glioblastoma D005909 27 associated lipids
Hyperplasia D006965 34 associated lipids
Adenoma D000236 40 associated lipids
Precancerous Conditions D011230 48 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (-)-Perillyl alcohol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Perillyl alcohol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Perillyl alcohol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Perillyl alcohol?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Perillyl alcohol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Perillyl alcohol?

Transgenic Model

Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with (-)-Perillyl alcohol

Download all related citations
Per page 10 20 50 100 | Total 165
Authors Title Published Journal PubMed Link
Bicas JL et al. Evaluation of the antioxidant and antiproliferative potential of bioflavors. 2011 Food Chem. Toxicol. pmid:21540069
Khan AQ et al. Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production. 2011 Toxicology pmid:20923693
de Saldanha da Gama Fischer J et al. Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol. 2011 J. Proteome Res. pmid:20806975
da Fonseca CO et al. Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma. 2011 J. Cancer Res. Clin. Oncol. pmid:20401670
Prado R et al. Nonmelanoma skin cancer chemoprevention. 2011 Dermatol Surg pmid:21895847
Kiran I Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium. 2011 Nat Prod Commun pmid:22312710
Cornelissen S et al. Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization. 2011 J. Ind. Microbiol. Biotechnol. pmid:21559976
Garcia DG et al. The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor. 2010 Mol. Cell. Biochem. pmid:20689980
Stratton SP et al. A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. 2010 Cancer Prev Res (Phila) pmid:20103724
Yeruva L et al. Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin. 2010 Anticancer Drugs pmid:19820395