(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
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Authors | Title | Published | Journal | PubMed Link |
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Wróblewska A | The epoxidation of limonene over the TS-1 and Ti-SBA-15 catalysts. | 2014 | Molecules | pmid:25460313 |
Nandurkar NS et al. | The identification of perillyl alcohol glycosides with improved antiproliferative activity. | 2014 | J. Med. Chem. | pmid:25121720 |
Hui Z et al. | Synthesis and antiproliferative effects of amino-modified perillyl alcohol derivatives. | 2014 | Molecules | pmid:24858099 |
Chen TC et al. | A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo. | 2014 | Mol. Cancer Ther. | pmid:24623736 |
Lefranc F et al. | 4-Bromo-2-(piperidin-1-yl)thiazol-5-yl-phenyl methanone (12b) inhibits Na+/K(+)-ATPase and Ras oncogene activity in cancer cells. | 2013 | Eur J Med Chem | pmid:23474907 |
Sundin T et al. | Disruption of an hTERT-mTOR-RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin. | 2013 | Mol. Cell. Biochem. | pmid:23283642 |
Koyama M et al. | Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction. | 2013 | Oncol. Rep. | pmid:23233050 |
Sultana S et al. | Perillyl alcohol as a protective modulator against rat hepatocarcinogenesis via amelioration of oxidative damage and cell proliferation. | 2013 | Hum Exp Toxicol | pmid:23536516 |
Sundin T et al. | eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase. | 2013 | Exp. Cell Res. | pmid:23747720 |
Silva MM et al. | Influence of GSTM1 and GSTT1 polymorphisms on the survival rate of patients with malignant glioma under perillyl alcohol-based therapy. | 2013 | Genet. Mol. Res. | pmid:23765968 |