MeSH term | MeSH ID | Detail |
---|---|---|
Brain Neoplasms | D001932 | 15 associated lipids |
Lymphoma, Mantle-Cell | D020522 | 5 associated lipids |
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Shi W and Gould MN | Induction of differentiation in neuro-2A cells by the monoterpene perillyl alcohol. | 1995 | Cancer Lett. | pmid:7656215 |
Hohl RJ and Lewis K | Differential effects of monoterpenes and lovastatin on RAS processing. | 1995 | J. Biol. Chem. | pmid:7615555 |
Phillips LR et al. | Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, an investigational antineoplastic agent, to the dog. | 1995 | Drug Metab. Dispos. | pmid:7587953 |
Alison M | Promoting apoptosis. | 1995 | Hum Exp Toxicol | pmid:7576838 |
Stark MJ et al. | Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol. | 1995 | Cancer Lett. | pmid:7553603 |
Opdyke DL | Monographs on fragrance raw materials. | 1981 | Food Cosmet Toxicol | pmid:7286874 |
pmid:29129690 | ||||
pmid:28594456 | ||||
pmid:28450161 | ||||
pmid:28314870 | ||||
pmid:28233648 | ||||
pmid:28044940 | ||||
pmid:27890582 | ||||
Ansari MA et al. | Anticandidal Effect and Mechanisms of Monoterpenoid, Perillyl Alcohol against Candida albicans. | 2016 | PLoS ONE | pmid:27627759 |
Chen TC et al. | Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases. | 2016 | Int J Mol Sci | pmid:27598140 |
pmid:27394002 | ||||
pmid:27325307 | ||||
pmid:27220072 | ||||
Song X et al. | Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer. | 2016 | Sci Rep | pmid:26949038 |
Andrade LN et al. | In Vivo Anti-Tumor Activity and Toxicological Evaluations of Perillaldehyde 8,9-Epoxide, a Derivative of Perillyl Alcohol. | 2016 | Int J Mol Sci | pmid:26742032 |