MeSH term | MeSH ID | Detail |
---|---|---|
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Khan AQ et al. | Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production. | 2011 | Toxicology | pmid:20923693 |
de Saldanha da Gama Fischer J et al. | Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol. | 2011 | J. Proteome Res. | pmid:20806975 |
da Fonseca CO et al. | Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma. | 2011 | J. Cancer Res. Clin. Oncol. | pmid:20401670 |
Prado R et al. | Nonmelanoma skin cancer chemoprevention. | 2011 | Dermatol Surg | pmid:21895847 |
Kiran I | Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium. | 2011 | Nat Prod Commun | pmid:22312710 |
Cornelissen S et al. | Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21559976 |
Farazuddin M et al. | Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles. | 2012 | Int J Nanomedicine | pmid:22275821 |
da Silveira Fd et al. | Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy. | 2012 | J. Cancer Res. Clin. Oncol. | pmid:22481252 |
Sundin T et al. | The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. | 2012 | Biochimie | pmid:22902867 |
Duelund L et al. | Influence of the active compounds of Perilla frutescens leaves on lipid membranes. | 2012 | J. Nat. Prod. | pmid:22272932 |