MeSH term | MeSH ID | Detail |
---|---|---|
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Luján HD et al. | Isoprenylation of proteins in the protozoan Giardia lamblia. | 1995 | Mol. Biochem. Parasitol. | pmid:8538683 |
Hohl RJ and Lewis K | Differential effects of monoterpenes and lovastatin on RAS processing. | 1995 | J. Biol. Chem. | pmid:7615555 |
Gelb MH et al. | The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol. | 1995 | Cancer Lett. | pmid:7767906 |
Shi W and Gould MN | Induction of differentiation in neuro-2A cells by the monoterpene perillyl alcohol. | 1995 | Cancer Lett. | pmid:7656215 |
Alison M | Promoting apoptosis. | 1995 | Hum Exp Toxicol | pmid:7576838 |
Phillips LR et al. | Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, an investigational antineoplastic agent, to the dog. | 1995 | Drug Metab. Dispos. | pmid:7587953 |
Mills JJ et al. | Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. | 1995 | Cancer Res. | pmid:7867007 |
Ren Z and Gould MN | Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. | 1994 | Cancer Lett. | pmid:8149348 |
Pan J et al. | [Constituents of essential oils from leaves, stems, and fruits of Perilla frutescens (L.) Britt]. | 1992 | Zhongguo Zhong Yao Za Zhi | pmid:1418538 |
Opdyke DL | Monographs on fragrance raw materials. | 1981 | Food Cosmet Toxicol | pmid:7286874 |
pmid: | ||||
pmid:29129690 | ||||
pmid:28450161 | ||||
pmid:28044940 | ||||
pmid:27394002 | ||||
pmid:27220072 | ||||
pmid:26475687 | ||||
pmid:25497898 | ||||
pmid:27325307 | ||||
pmid:27890582 |