MeSH term | MeSH ID | Detail |
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Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
Lymphoma, B-Cell | D016393 | 24 associated lipids |
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Samaila D et al. | Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro. | 2004 Sep-Oct | Anticancer Res. | pmid:15517920 |
DA Fonseca CO et al. | Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation. | 2013 | Anticancer Res. | pmid:24324108 |
d'Alessio PA et al. | Skin repair properties of d-Limonene and perillyl alcohol in murine models. | 2014 | Antiinflamm Antiallergy Agents Med Chem | pmid:24160248 |
van Beilen JB et al. | Biocatalytic production of perillyl alcohol from limonene by using a novel Mycobacterium sp. cytochrome P450 alkane hydroxylase expressed in Pseudomonas putida. | 2005 | Appl. Environ. Microbiol. | pmid:15811996 |
Peffley DM et al. | Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells. | 2007 | Arch. Biochem. Biophys. | pmid:17601486 |
da Fonseca CO et al. | Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol. | 2008 Jul-Aug | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:18726148 |
D'Alincourt Salazar M et al. | Intranasal administration of perillyl alcohol activates peripheral and bronchus-associated immune system in vivo. | 2014 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:24257817 |
Imamura M et al. | Perillyl alcohol suppresses antigen-induced immune responses in the lung. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24309112 |
Ren Z et al. | Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells. | 1997 | Biochem. Pharmacol. | pmid:9296357 |
Sundin T et al. | The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. | 2012 | Biochimie | pmid:22902867 |