Lantry LE et al. |
Chemopreventive efficacy of promising farnesyltransferase inhibitors. |
2000 |
Exp. Lung Res. |
pmid:11195470
|
Si MS and Imagawa DK |
Prenylation inhibitors to treat proliferative renal disease. |
2000 |
Lancet |
pmid:10791545
|
Boon PJ et al. |
Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat. |
2000 |
Toxicol. Appl. Pharmacol. |
pmid:10936079
|
Hudes GR et al. |
Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies. |
2000 |
Clin. Cancer Res. |
pmid:10955786
|
Löw-Baselli A et al. |
Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note. |
2000 |
Carcinogenesis |
pmid:11023545
|
Unlu S et al. |
Perillyl alcohol, an inhibitor of geranylgeranyl transferase, induces apoptosis of immortalized human vascular smooth muscle cells in vitro. |
2000 |
J. Cardiovasc. Pharmacol. |
pmid:10672871
|
Ripple GH et al. |
Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day. |
2000 |
Clin. Cancer Res. |
pmid:10690515
|
Miyazawa M et al. |
Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes. |
2002 |
Chem. Res. Toxicol. |
pmid:11800592
|
Clark SS et al. |
Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest. |
2002 |
Leukemia |
pmid:11840288
|
Shi W and Gould MN |
Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol. |
2002 |
Carcinogenesis |
pmid:11756234
|
Bardon S et al. |
Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression. |
2002 |
Cancer Lett. |
pmid:12175534
|
Lluria-Prevatt M et al. |
Effects of perillyl alcohol on melanoma in the TPras mouse model. |
2002 |
Cancer Epidemiol. Biomarkers Prev. |
pmid:12050099
|
Bailey HH et al. |
A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96. |
2002 |
Gynecol. Oncol. |
pmid:12051875
|
Teruszkin Balassiano I et al. |
Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model. |
2002 |
Int. J. Mol. Med. |
pmid:12430008
|
Meadows SM et al. |
Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer. |
2002 |
Int J Gastrointest Cancer |
pmid:12794248
|
Miyazawa M et al. |
Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes. |
2002 |
Drug Metab. Dispos. |
pmid:11950794
|
Murren JR et al. |
Phase I study of perillyl alcohol in patients with refractory malignancies. |
2002 Mar-Apr |
Cancer Biol. Ther. |
pmid:12170772
|
Burke YD et al. |
Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention. |
2002 Nov-Dec |
Anticancer Res. |
pmid:12530055
|
Kennedy S et al. |
Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries. |
2003 |
Eur. J. Pharmacol. |
pmid:14637181
|
Ahn KJ et al. |
Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia. |
2003 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:14529788
|
Clark SS et al. |
Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion. |
2003 |
Clin. Cancer Res. |
pmid:14555523
|
Liu G et al. |
Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer. |
2003 |
Invest New Drugs |
pmid:14578686
|
Russell J and Ling CC |
Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells. |
2003 |
Eur. J. Cancer |
pmid:14522384
|
Holstein SA and Hohl RJ |
Monoterpene regulation of Ras and Ras-related protein expression. |
2003 |
J. Lipid Res. |
pmid:12671036
|
Rajesh D et al. |
Perillyl alcohol as a radio-/chemosensitizer in malignant glioma. |
2003 |
J. Biol. Chem. |
pmid:12805388
|
Liston BW et al. |
Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. |
2003 |
Cancer Res. |
pmid:12750258
|
Azzoli CG et al. |
A phase I trial of perillyl alcohol in patients with advanced solid tumors. |
2003 |
Cancer Chemother. Pharmacol. |
pmid:12695855
|
Morgan-Meadows S et al. |
Phase I trial of perillyl alcohol administered four times daily continuously. |
2003 |
Cancer Chemother. Pharmacol. |
pmid:12904896
|
Rajesh D and Howard SP |
Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells. |
2003 |
Prostate |
pmid:12886519
|
Elegbede JA et al. |
Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro. |
2003 |
Life Sci. |
pmid:14511768
|
Bailey HH et al. |
A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15205914
|
Loutrari H et al. |
Perillyl alcohol is an angiogenesis inhibitor. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15210838
|
Gupta A and Myrdal PB |
Development of a perillyl alcohol topical cream formulation. |
2004 |
Int J Pharm |
pmid:14706249
|
Stearns V et al. |
A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia. |
2004 |
Clin. Cancer Res. |
pmid:15569989
|
Xu M et al. |
Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects. |
2004 |
Toxicol. Appl. Pharmacol. |
pmid:14998688
|
Yuri T et al. |
Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo. |
2004 |
Breast Cancer Res. Treat. |
pmid:15026623
|
Chen Y and Hu D |
Effects of POH in combination with STI571 on the proliferation and apoptosis of K562 cells. |
2004 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:15165112
|
Samaila D et al. |
Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro. |
2004 Sep-Oct |
Anticancer Res. |
pmid:15517920
|
Gupta A et al. |
An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation. |
2005 |
J Pharm Biomed Anal |
pmid:15740902
|
Fernandes J et al. |
Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells. |
2005 |
Oncol. Rep. |
pmid:15809762
|
Courdavault V et al. |
CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells. |
2005 |
Plant Mol. Biol. |
pmid:15952070
|
Bassi AM et al. |
Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo. |
2005 |
J. Biomed. Sci. |
pmid:15959631
|
Del Toro-Arreola S et al. |
Effect of D-limonene on immune response in BALB/c mice with lymphoma. |
2005 |
Int. Immunopharmacol. |
pmid:15778119
|
Berchtold CM et al. |
Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway. |
2005 |
Cancer Res. |
pmid:16166337
|
van Beilen JB et al. |
Biocatalytic production of perillyl alcohol from limonene by using a novel Mycobacterium sp. cytochrome P450 alkane hydroxylase expressed in Pseudomonas putida. |
2005 |
Appl. Environ. Microbiol. |
pmid:15811996
|
Chan NL et al. |
Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells. |
2006 |
Toxicol. Appl. Pharmacol. |
pmid:16307765
|
Chung BH et al. |
Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells. |
2006 |
Cancer Lett. |
pmid:16029925
|
Clark SS |
Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells. |
2006 |
Oncology |
pmid:16439861
|
da Fonseca CO et al. |
Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol. |
2006 |
Surg Neurol |
pmid:16427438
|
Fischer Jde S et al. |
Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549. |
2006 |
J. Exp. Ther. Oncol. |
pmid:17024970
|