| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Brain Neoplasms | D001932 | 15 associated lipids |
(-)-Perillyl alcohol
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Perillyl alcohol?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Perillyl alcohol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Perillyl alcohol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Perillyl alcohol?
There are no associated biomedical information in the current reference collection.
What genes are associated with (-)-Perillyl alcohol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Perillyl alcohol?
Transgenic Model
Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with (-)-Perillyl alcohol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Seifert A et al. | An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1. | 2011 | Chembiochem | pmid:21591046 |
| Miyazawa M et al. | Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes. | 2002 | Chem. Res. Toxicol. | pmid:11800592 |
| Chaudhary SC et al. | Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis. | 2009 | Chem. Biol. Interact. | pmid:19161993 |
| Wei X et al. | Perillyl alcohol inhibits TCR-mediated [Ca(2+)](i) signaling, alters cell shape and motility, and induces apoptosis in T lymphocytes. | 2000 | Cell. Immunol. | pmid:10805968 |
| Stayrook KR et al. | Induction of the apoptosis-promoting protein Bak by perillyl alcohol in pancreatic ductal adenocarcinoma relative to untransformed ductal epithelial cells. | 1997 | Carcinogenesis | pmid:9276644 |
| Satomi Y et al. | Induction of AP-1 activity by perillyl alcohol in breast cancer cells. | 1999 | Carcinogenesis | pmid:10506111 |
| Shi W and Gould MN | Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol. | 2002 | Carcinogenesis | pmid:11756234 |
| Löw-Baselli A et al. | Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note. | 2000 | Carcinogenesis | pmid:11023545 |
| Barthelman M et al. | Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation. | 1998 | Cancer Res. | pmid:9485025 |
| Reddy BS et al. | Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. | 1997 | Cancer Res. | pmid:9012468 |