| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Pleurisy | D010998 | 20 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
Carvacrol
Carvacrol is a lipid of Prenol Lipids (PR) class. Carvacrol is associated with abnormalities such as Consumption-archaic term for TB, Disintegration (morphologic abnormality), Infection, Corn of toe and Candidiasis of vagina. The involved functions are known as Stereochemistry, Anabolism, Oxidation, Process and Binding (Molecular Function). Carvacrol often locates in Skin, Nerve Tissue, Membrane, Endothelium and Plasma membrane. The associated genes with Carvacrol are P4HTM gene, TRPV3 gene, TRPV1 gene, TRPV2 gene and TRPV4 gene. The related lipids are Fatty Acids, Lipopolysaccharides, Octanols, Micelles and butyrate.
Cross Reference
Introduction
To understand associated biological information of Carvacrol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Carvacrol?
Carvacrol is suspected in Candidiasis of vagina, Infection, Infestation, Acquired partial lipodystrophy, Urticaria, Periodontitis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Carvacrol
PubChem Associated disorders and diseases
What pathways are associated with Carvacrol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Carvacrol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Carvacrol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Carvacrol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Carvacrol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Carvacrol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Carvacrol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang P et al. | The Neuroprotective Effects of Carvacrol on Ethanol-Induced Hippocampal Neurons Impairment via the Antioxidative and Antiapoptotic Pathways. | 2017 | Oxid Med Cell Longev | pmid:28191274 |
| Meents JE et al. | Sensitization of TRPA1 by Protein Kinase A. | 2017 | PLoS ONE | pmid:28076424 |
| Figueiredo MB et al. | Lethal and sublethal effects of essential oil of Lippia sidoides (Verbenaceae) and monoterpenes on Chagas' disease vector Rhodnius prolixus. | 2017 | Mem. Inst. Oswaldo Cruz | pmid:27878214 |
| Vasconcelos SECB et al. | Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus. | 2017 | BMC Complement Altern Med | pmid:28915875 |
| Sivaranjani A et al. | Chemopreventive effect of carvacrol on 1,2-dimethylhydrazine induced experimental colon carcinogenesis. | 2016 Apr-Jun | J Cancer Res Ther | pmid:27461646 |
| Xavier FJ et al. | Synthesis and In Vitro Anti Leishmania amazonensis Biological Screening of Morita-Baylis-Hillman Adducts Prepared from Eugenol, Thymol and Carvacrol. | 2016 | Molecules | pmid:27834831 |
| Luo Y et al. | Carvacrol Alleviates Prostate Cancer Cell Proliferation, Migration, and Invasion through Regulation of PI3K/Akt and MAPK Signaling Pathways. | 2016 | Oxid Med Cell Longev | pmid:27803760 |
| Costa-Júnior LM et al. | Acaricidal efficacies of Lippia gracilis essential oil and its phytochemicals against organophosphate-resistant and susceptible strains of Rhipicephalus (Boophilus) microplus. | 2016 | Vet. Parasitol. | pmid:27692332 |
| Burt SA et al. | Cinnamaldehyde, Carvacrol and Organic Acids Affect Gene Expression of Selected Oxidative Stress and Inflammation Markers in IPEC-J2 Cells Exposed to Salmonella typhimurium. | 2016 | Phytother Res | pmid:27561686 |
| Khosravi AR and Erle DJ | Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol. | 2016 | PLoS ONE | pmid:27463381 |
| Meents JE et al. | Agonist-induced sensitisation of the irritant receptor ion channel TRPA1. | 2016 | J. Physiol. (Lond.) | pmid:27307078 |
| Deepak V et al. | Carvacrol Inhibits Osteoclastogenesis and Negatively Regulates the Survival of Mature Osteoclasts. | 2016 | Biol. Pharm. Bull. | pmid:27170515 |
| Ran C et al. | Thymol and Carvacrol Affect Hybrid Tilapia through the Combination of Direct Stimulation and an Intestinal Microbiota-Mediated Effect: Insights from a Germ-Free Zebrafish Model. | 2016 | J. Nutr. | pmid:27075912 |
| Andre WP et al. | Comparative efficacy and toxic effects of carvacryl acetate and carvacrol on sheep gastrointestinal nematodes and mice. | 2016 | Vet. Parasitol. | pmid:26872928 |
| El-Sayed el-SM et al. | Thymol and Carvacrol Prevent Doxorubicin-Induced Cardiotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats. | 2016 | J. Biochem. Mol. Toxicol. | pmid:26387986 |
| Games E et al. | Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema. | 2016 | Molecules | pmid:27775634 |
| Nóbrega RO et al. | Investigation of the antifungal activity of carvacrol against strains of Cryptococcus neoformans. | 2016 | Pharm Biol | pmid:27225838 |
| Cui ZW et al. | Carvacrol protects neuroblastoma SH-SY5Y cells against Fe(2+)-induced apoptosis by suppressing activation of MAPK/JNK-NF-κB signaling pathway. | 2015 | Acta Pharmacol. Sin. | pmid:26592517 |
| Kim JH et al. | Augmenting the Activity of Monoterpenoid Phenols against Fungal Pathogens Using 2-Hydroxy-4-methoxybenzaldehyde that Target Cell Wall Integrity. | 2015 | Int J Mol Sci | pmid:26569223 |
| Guevara L et al. | Impact of Moderate Heat, Carvacrol, and Thymol Treatments on the Viability, Injury, and Stress Response of Listeria monocytogenes. | 2015 | Biomed Res Int | pmid:26539510 |
| Feketa VV and Marrelli SP | Systemic Administration of the TRPV3 Ion Channel Agonist Carvacrol Induces Hypothermia in Conscious Rodents. | 2015 | PLoS ONE | pmid:26528923 |
| Novato TP et al. | Evaluation of the combined effect of thymol, carvacrol and (E)-cinnamaldehyde on Amblyomma sculptum (Acari: Ixodidae) and Dermacentor nitens (Acari: Ixodidae) larvae. | 2015 | Vet. Parasitol. | pmid:26346899 |
| Ahmed HH et al. | Implications of Sex Hormone Receptor Gene Expression in the Predominance of Hepatocellular Carcinoma in Males: Role of Natural Products. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26163620 |
| Patricelli D et al. | Plant defences against ants provide a pathway to social parasitism in butterflies. | 2015 | Proc. Biol. Sci. | pmid:26156773 |
| Peng G et al. | Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1. | 2015 | Cell Rep | pmid:26146083 |
| Yuan G et al. | Physical Properties, Antioxidant and Antimicrobial Activity of Chitosan Films Containing Carvacrol and Pomegranate Peel Extract. | 2015 | Molecules | pmid:26083037 |
| Pirgozliev V et al. | Partitioning of dietary energy of chickens fed maize- or wheat-based diets with and without a commercial blend of phytogenic feed additives. | 2015 | J. Anim. Sci. | pmid:26020191 |
| Chaillot J et al. | The Monoterpene Carvacrol Generates Endoplasmic Reticulum Stress in the Pathogenic Fungus Candida albicans. | 2015 | Antimicrob. Agents Chemother. | pmid:26014932 |
| Chen WL et al. | Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion. | 2015 | Oncotarget | pmid:25965832 |
| Trailović SM et al. | Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action. | 2015 | Parasitol. Res. | pmid:25944741 |
| Boskabady MH and Gholami Mahtaj L | Lung inflammation changes and oxidative stress induced by cigarette smoke exposure in guinea pigs affected by Zataria multiflora and its constituent, carvacrol. | 2015 | BMC Complement Altern Med | pmid:25881210 |
| Cacciatore I et al. | Carvacrol codrugs: a new approach in the antimicrobial plan. | 2015 | PLoS ONE | pmid:25859852 |
| Mith H et al. | The impact of oregano (Origanum heracleoticum) essential oil and carvacrol on virulence gene transcription by Escherichia coli O157:H7. | 2015 | FEMS Microbiol. Lett. | pmid:25790499 |
| Yadav MK et al. | Eugenol: a phyto-compound effective against methicillin-resistant and methicillin-sensitive Staphylococcus aureus clinical strain biofilms. | 2015 | PLoS ONE | pmid:25781975 |
| Rasooly R et al. | Plant compounds enhance the assay sensitivity for detection of active Bacillus cereus toxin. | 2015 | Toxins (Basel) | pmid:25767986 |
| Shaaban HA and Edris AE | Factors affecting the phase behavior and antimicrobial activity of carvacrol microemulsions. | 2015 | J Oleo Sci | pmid:25766929 |
| Chen W et al. | TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury. | 2015 | Mol Brain | pmid:25761704 |
| Field D et al. | Efficacies of nisin A and nisin V semipurified preparations alone and in combination with plant essential oils for controlling Listeria monocytogenes. | 2015 | Appl. Environ. Microbiol. | pmid:25662980 |
| Sarrazin SL et al. | Antimicrobial and seasonal evaluation of the carvacrol-chemotype oil from Lippia origanoides kunth. | 2015 | Molecules | pmid:25625681 |
| Lansdell SJ et al. | Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site. | 2015 | Mol. Pharmacol. | pmid:25338672 |
| Pires PW et al. | Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26453324 |
| Espina L et al. | Individual Constituents from Essential Oils Inhibit Biofilm Mass Production by Multi-Drug Resistant Staphylococcus aureus. | 2015 | Molecules | pmid:26102069 |
| Andrade-Ochoa S et al. | Quantitative structure-activity relationship of molecules constituent of different essential oils with antimycobacterial activity against Mycobacterium tuberculosis and Mycobacterium bovis. | 2015 | BMC Complement Altern Med | pmid:26400221 |
| Yousefzadi M et al. | Toxicity of essential oil of Satureja khuzistanica: in vitro cytotoxicity and anti-microbial activity. | 2014 Jan-Mar | J Immunotoxicol | pmid:23662744 |
| Zeidán-Chuliá F et al. | Focussed microarray analysis of apoptosis in periodontitis and its potential pharmacological targeting by carvacrol. | 2014 | Arch. Oral Biol. | pmid:24631628 |
| Mooyottu S et al. | Carvacrol and trans-cinnamaldehyde reduce Clostridium difficile toxin production and cytotoxicity in vitro. | 2014 | Int J Mol Sci | pmid:24625665 |
| Bravo D et al. | A mixture of carvacrol, cinnamaldehyde, and capsicum oleoresin improves energy utilization and growth performance of broiler chickens fed maize-based diet. | 2014 | J. Anim. Sci. | pmid:24496847 |
| Banji OJ et al. | Combination of carvacrol with methotrexate suppresses Complete Freund's Adjuvant induced synovial inflammation with reduced hepatotoxicity in rats. | 2014 | Eur. J. Pharmacol. | pmid:24333217 |
| Neyret C et al. | Plant-derived compounds as natural antimicrobials to control paper mill biofilms. | 2014 | J. Ind. Microbiol. Biotechnol. | pmid:24170384 |
| Medeiros Barreto H et al. | Phytochemical prospection and modulation of antibiotic activity in vitro by Lippia origanoides H.B.K. in methicillin resistant Staphylococcus aureus. | 2014 | Biomed Res Int | pmid:24683545 |