Menthofuran

Menthofuran is a lipid of Prenol Lipids (PR) class. The involved functions are known as Process, conjugation, radiochemical, Synthesis and Enterohepatic Circulation. Menthofuran often locates in Microsomes. The associated genes with Menthofuran are 4S-limonene synthase, CYP1A2 gene, CYP2E1 gene, CYP2D6 gene and CYP2C9 gene.

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Introduction

To understand associated biological information of Menthofuran, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Menthofuran?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Menthofuran

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Menthofuran?

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What functions are associated with Menthofuran?


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What lipids are associated with Menthofuran?

There are no associated biomedical information in the current reference collection.

What genes are associated with Menthofuran?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Menthofuran?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Menthofuran

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Maffei M et al. Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential. 2001 Phytochemistry pmid:11672734
Bertea CM et al. Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene. 2001 Arch. Biochem. Biophys. pmid:11396930
Taavitsainen P et al. In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene. 2001 Drug Metab. Dispos. pmid:11181487
Engel W In vivo studies on the metabolism of the monoterpene pulegone in humans using the metabolism of ingestion-correlated amounts (MICA) approach: explanation for the toxicity differences between (S)-(-)- and (R)-(+)-pulegone. 2003 J. Agric. Food Chem. pmid:14558782
Chen LJ et al. Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites. 2003 Drug Metab. Dispos. pmid:12975329
Turner GW and Croteau R Organization of monoterpene biosynthesis in Mentha. Immunocytochemical localizations of geranyl diphosphate synthase, limonene-6-hydroxylase, isopiperitenol dehydrogenase, and pulegone reductase. 2004 Plant Physiol. pmid:15542490
Latham JR et al. The mutational consequences of plant transformation. 2006 J. Biomed. Biotechnol. pmid:16883050
Gyoubu K and Miyazawa M In vitro metabolism of (-)-camphor using human liver microsomes and CYP2A6. 2007 Biol. Pharm. Bull. pmid:17268056
Ferguson LJ et al. 14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats. 2007 J. Toxicol. Environ. Health Part A pmid:17687727
Miyazawa M and Gyoubu K Metabolism of (-)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes. 2007 Xenobiotica pmid:17484521
Sapra B et al. Percutaneous permeation enhancement by terpenes: mechanistic view. 2008 AAPS J pmid:18446512
Apel MA et al. Chemical composition and toxicity of the essential oils from Cunila species (Lamiaceae) on the cattle tick Rhipicephalus (Boophilus) microplus. 2009 Parasitol. Res. pmid:19421776
Rios-Estepa R et al. Mathematical modeling-guided evaluation of biochemical, developmental, environmental, and genotypic determinants of essential oil composition and yield in peppermint leaves. 2010 Plant Physiol. pmid:20147490
Khojasteh SC et al. Metabolism and toxicity of menthofuran in rat liver slices and in rats. 2010 Chem. Res. Toxicol. pmid:20945912
Ibrahim MA et al. Elevation of night-time temperature increases terpenoid emissions from Betula pendula and Populus tremula. 2010 J. Exp. Bot. pmid:20181662
Yu S et al. Quantitative comparative analysis of the bio-active and toxic constituents of leaves and spikes of Schizonepeta tenuifolia at different harvesting times. 2011 Int J Mol Sci pmid:22072908
Atsbaha Zebelo S et al. Chrysolina herbacea modulates terpenoid biosynthesis of Mentha aquatica L. 2011 PLoS ONE pmid:21408066
Santoro MV et al. Volatile organic compounds from rhizobacteria increase biosynthesis of essential oils and growth parameters in peppermint (Mentha piperita). 2011 Plant Physiol. Biochem. pmid:21843946
Miyazawa M et al. Metabolism of (+)- and (-)-menthols by CYP2A6 in human liver microsomes. 2011 J Oleo Sci pmid:21343660
Döll-Boscardin PM et al. In Vitro Cytotoxic Potential of Essential Oils of Eucalyptus benthamii and Its Related Terpenes on Tumor Cell Lines. 2012 Evid Based Complement Alternat Med pmid:22645627
Bertoli A et al. In vitro production of M. × piperita not containing pulegone and menthofuran. 2012 Acta Biochim. Pol. pmid:22946028
Rossi YE et al. Molecular response of Musca domestica L. to Mintostachys verticillata essential oil, (4R)+-pulegone and menthone. 2012 Fitoterapia pmid:22155595
Kramlinger VM et al. Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol. 2012 Chem. Biol. Interact. pmid:22486895
Haigou R and Miyazawa M Metabolism of (+)-terpinen-4-ol by cytochrome P450 enzymes in human liver microsomes. 2012 J Oleo Sci pmid:22188805
Da Rocha MS et al. Mode of action of pulegone on the urinary bladder of F344 rats. 2012 Toxicol. Sci. pmid:22499580