Thymol

Thymol is a lipid of Prenol Lipids (PR) class. Thymol is associated with abnormalities such as Anemia, end organ damage, Dental caries, CLEFT LIP, CONGENITAL HEALED and Wiskott-Aldrich Syndrome. The involved functions are known as synergism, antagonists, Metabolic Inhibition, Pressure- physical agent and Drug Interactions. Thymol often locates in Mucous Membrane, apical membrane, Protoplasm, Extracellular and Serosal. The associated genes with Thymol are HIST1H1C gene, TRPA1 gene, MERTK wt Allele, SLC12A2 gene and TRPV3 gene. The related lipids are Propionate, Pinene, palmitoleic acid, pentadecanoic acid and stearic acid.

Cross Reference

Introduction

To understand associated biological information of Thymol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thymol?

Thymol is suspected in Anemia, Infestation, end organ damage, CLEFT LIP, CONGENITAL HEALED, Echinococcosis, Malaria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thymol

MeSH term MeSH ID Detail
Dermatitis, Contact D003877 59 associated lipids
Lung Diseases D008171 37 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Dental Caries D003731 6 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Nerve Compression Syndromes D009408 4 associated lipids
Liver Diseases D008107 31 associated lipids
Occupational Diseases D009784 42 associated lipids
Per page 10 20 50 | Total 44

PubChem Associated disorders and diseases

What pathways are associated with Thymol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thymol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thymol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thymol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thymol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Thymol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thymol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thymol

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Per page 10 20 50 100 | Total 2105
Authors Title Published Journal PubMed Link
Reginato CF et al. Antifungal activity of synthetic antiseptics and natural compounds against Candida dubliniensis before and after in vitro fluconazole exposure. 2017 Jan-Feb Rev. Soc. Bras. Med. Trop. pmid:28327805
Figueiredo MB et al. Lethal and sublethal effects of essential oil of Lippia sidoides (Verbenaceae) and monoterpenes on Chagas' disease vector Rhodnius prolixus. 2017 Mem. Inst. Oswaldo Cruz pmid:27878214
Riasat M et al. The constituents of essential oil in leaves of Karaj accession of Trigonella foenum graecum. 2017 Nat. Prod. Res. pmid:28278666
Dong LM et al. Two New Thymol Derivatives from the Roots of Ageratina adenophora. 2017 Molecules pmid:28397757
Wu H et al. Thymol mitigates lipopolysaccharide-induced endometritis by regulating the TLR4- and ROS-mediated NF-κB signaling pathways. 2017 Oncotarget pmid:28223539
Gracia MJ et al. Field efficacy of acaricides against Varroa destructor. 2017 PLoS ONE pmid:28158303
Kissels W et al. Short communication: Interaction of the isomers carvacrol and thymol with the antibiotics doxycycline and tilmicosin: In vitro effects against pathogenic bacteria commonly found in the respiratory tract of calves. 2017 J. Dairy Sci. pmid:28012625
Zhang W et al. Inhibitory Effects of Emodin, Thymol, and Astragalin on Leptospira interrogans-Induced Inflammatory Response in the Uterine and Endometrium Epithelial Cells of Mice. 2017 Inflammation pmid:28210912
Marcial GE et al. Influence of oregano essential oil on traditional Argentinean cheese elaboration: Effect on lactic starter cultures. 2016 Jul - Sep Rev. Argent. Microbiol. pmid:27577090
Xavier FJ et al. Synthesis and In Vitro Anti Leishmania amazonensis Biological Screening of Morita-Baylis-Hillman Adducts Prepared from Eugenol, Thymol and Carvacrol. 2016 Molecules pmid:27834831
Costa-Júnior LM et al. Acaricidal efficacies of Lippia gracilis essential oil and its phytochemicals against organophosphate-resistant and susceptible strains of Rhipicephalus (Boophilus) microplus. 2016 Vet. Parasitol. pmid:27692332
Khosravi AR and Erle DJ Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol. 2016 PLoS ONE pmid:27463381
Ran C et al. Thymol and Carvacrol Affect Hybrid Tilapia through the Combination of Direct Stimulation and an Intestinal Microbiota-Mediated Effect: Insights from a Germ-Free Zebrafish Model. 2016 J. Nutr. pmid:27075912
Samii SS et al. Effects of limonene on ruminal concentrations, fermentation, and lysine degradation in cattle. 2016 J. Anim. Sci. pmid:27695807
El-Sayed el-SM et al. Thymol and Carvacrol Prevent Doxorubicin-Induced Cardiotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats. 2016 J. Biochem. Mol. Toxicol. pmid:26387986
Ye X et al. Thymol Mitigates Cadmium Stress by Regulating Glutathione Levels and Reactive Oxygen Species Homeostasis in Tobacco Seedlings. 2016 Molecules pmid:27754435
Bustos-Brito C et al. Antidiarrheal Thymol Derivatives from Ageratina glabrata. Structure and Absolute Configuration of 10-Benzoyloxy-8,9-epoxy-6-hydroxythymol Isobutyrate. 2016 Molecules pmid:27626392
Gao T et al. The Fungicidal Activity of Thymol against Fusarium graminearum via Inducing Lipid Peroxidation and Disrupting Ergosterol Biosynthesis. 2016 Molecules pmid:27322238
Sharif-Abdullah SS et al. The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial. 2016 Singapore Med J pmid:27211885
Shen Q et al. ROS Involves the Fungicidal Actions of Thymol against Spores of Aspergillus flavus via the Induction of Nitric Oxide. 2016 PLoS ONE pmid:27196096
Kang SH et al. Anticancer Effect of Thymol on AGS Human Gastric Carcinoma Cells. 2016 J. Microbiol. Biotechnol. pmid:26437948
Ribeiro AR et al. Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K(+) channels, and gastric mucus secretion. 2016 Chem. Biol. Interact. pmid:26689173
Games E et al. Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema. 2016 Molecules pmid:27775634
Dzhavakhiya VG et al. Effect of Various Compounds Blocking the Colony Pigmentation on the Aflatoxin B1 Production by Aspergillus flavus. 2016 Toxins (Basel) pmid:27801823
Bizhang M et al. Effect of 10% fluoride on the remineralization of dentin in situ. 2015 Nov-Dec J Appl Oral Sci pmid:26814458
Witkowska-Banaszczak E et al. IN-VITRO ANTIMICROBIAL ACTIVITY OF BRONCHOSOL. 2015 Mar-Apr Acta Pol Pharm pmid:26642688
Kim JH et al. Augmenting the Activity of Monoterpenoid Phenols against Fungal Pathogens Using 2-Hydroxy-4-methoxybenzaldehyde that Target Cell Wall Integrity. 2015 Int J Mol Sci pmid:26569223
Guevara L et al. Impact of Moderate Heat, Carvacrol, and Thymol Treatments on the Viability, Injury, and Stress Response of Listeria monocytogenes. 2015 Biomed Res Int pmid:26539510
Novato TP et al. Evaluation of the combined effect of thymol, carvacrol and (E)-cinnamaldehyde on Amblyomma sculptum (Acari: Ixodidae) and Dermacentor nitens (Acari: Ixodidae) larvae. 2015 Vet. Parasitol. pmid:26346899
Field D et al. Efficacies of nisin A and nisin V semipurified preparations alone and in combination with plant essential oils for controlling Listeria monocytogenes. 2015 Appl. Environ. Microbiol. pmid:25662980
Lansdell SJ et al. Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site. 2015 Mol. Pharmacol. pmid:25338672
Biller OM et al. Possible Synergistic Effects of Thymol and Nicotine Against Crithidia bombi Parasitism in Bumble Bees. 2015 PLoS ONE pmid:26657643
Labib GS and Aldawsari H Innovation of natural essential oil-loaded Orabase for local treatment of oral candidiasis. 2015 Drug Des Devel Ther pmid:26170621
Faraone N et al. Plant Essential Oils Synergize and Antagonize Toxicity of Different Conventional Insecticides against Myzus persicae (Hemiptera: Aphididae). 2015 PLoS ONE pmid:26010088
de Castro RD et al. Antifungal activity and mode of action of thymol and its synergism with nystatin against Candida species involved with infections in the oral cavity: an in vitro study. 2015 BMC Complement Altern Med pmid:26601661
Thibodeau A et al. Chicken Caecal Microbiome Modifications Induced by Campylobacter jejuni Colonization and by a Non-Antibiotic Feed Additive. 2015 PLoS ONE pmid:26161743
Grilli E et al. Impact of dietary organic acids and botanicals on intestinal integrity and inflammation in weaned pigs. 2015 BMC Vet. Res. pmid:25889654
Zhang LW et al. Safety assessment of potential food ingredients in canine hepatocytes. 2015 Food Chem. Toxicol. pmid:25660481
Cossu A et al. Antifungal activity against Candida albicans of starch Pickering emulsion with thymol or amphotericin B in suspension and calcium alginate films. 2015 Int J Pharm pmid:26231107
Aman S et al. Antimicrobial polyphenols from small tropical fruits, tea and spice oilseeds. 2014 Food Sci Technol Int pmid:23703103
Price KL and Lummis SC An atypical residue in the pore of Varroa destructor GABA-activated RDL receptors affects picrotoxin block and thymol modulation. 2014 Insect Biochem. Mol. Biol. pmid:25460510
Li H et al. Antibacterial activity and mechanism of action of Monarda punctata essential oil and its main components against common bacterial pathogens in respiratory tract. 2014 Int J Clin Exp Pathol pmid:25550774
Gallucci MN et al. In vitro activity of natural phenolic compounds against fluconazole-resistant Candida species: a quantitative structure-activity relationship analysis. 2014 J. Appl. Microbiol. pmid:24387763
Llana-Ruiz-Cabello M et al. Cytotoxicity and morphological effects induced by carvacrol and thymol on the human cell line Caco-2. 2014 Food Chem. Toxicol. pmid:24326232
Bitu Vde C et al. Chemical composition of the essential oil of Lippia gracilis Schauer leaves and its potential as modulator of bacterial resistance. 2014 Nat. Prod. Res. pmid:24479735
Zhang Y et al. Fabrication, characterization and antimicrobial activities of thymol-loaded zein nanoparticles stabilized by sodium caseinate-chitosan hydrochloride double layers. 2014 Food Chem pmid:24001841
Matos RS et al. Determination of the susceptibility of unengorged larvae and engorged females of Rhipicephalus microplus (Acari: Ixodidae) to different methods of dissolving thymol. 2014 Parasitol. Res. pmid:24292541
Haque MR et al. Monoterpene phenolic compound thymol prevents high fat diet induced obesity in murine model. 2014 Toxicol. Mech. Methods pmid:24175857
Sancheti J et al. Characterization of anticonvulsant and antiepileptogenic potential of thymol in various experimental models. 2014 Naunyn Schmiedebergs Arch. Pharmacol. pmid:24065087
Carayon JL et al. Thymol as an alternative to pesticides: persistence and effects of Apilife Var on the phototactic behavior of the honeybee Apis mellifera. 2014 Environ Sci Pollut Res Int pmid:24043507