Perillic acid

Perillic acid is a lipid of Prenol Lipids (PR) class. The involved functions are known as Membrane Potential, Mitochondrial, Neuroprotection, inhibitors, Protein Geranylgeranylation and mitochondrial depolarization. Perillic acid often locates in Membrane and Extracellular. The associated genes with Perillic acid are RAB3A gene and neutrophil cytosol factor 67K.

Cross Reference

Introduction

To understand associated biological information of Perillic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Perillic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Perillic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Perillic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Perillic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Perillic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Perillic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Perillic acid

Download all related citations
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Authors Title Published Journal PubMed Link
pmid:
Hardcastle IR et al. Inhibition of protein prenylation by metabolites of limonene. 1999 Biochem. Pharmacol. pmid:10075086
Boon PJ et al. Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat. 2000 Toxicol. Appl. Pharmacol. pmid:10936079
Hudes GR et al. Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies. 2000 Clin. Cancer Res. pmid:10955786
Cheng QF et al. Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. 2001 Exp. Eye Res. pmid:11446774
Ferri N et al. Effect of S(-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation. 2001 Biochem. Pharmacol. pmid:11755117
Choy WY et al. Role of mitogen-activated protein kinase pathway in acetylcholine-mediated in vitro relaxation of rat pulmonary artery. 2002 Eur. J. Pharmacol. pmid:11755166
Bardon S et al. Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression. 2002 Cancer Lett. pmid:12175534
Chow HH et al. Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene content. 2002 Cancer Epidemiol. Biomarkers Prev. pmid:12433729
pmid:12451324