MeSH term | MeSH ID | Detail |
---|---|---|
Prostatic Neoplasms | D011471 | 126 associated lipids |
Perillic acid is a lipid of Prenol Lipids (PR) class. The involved functions are known as Membrane Potential, Mitochondrial, Neuroprotection, inhibitors, Protein Geranylgeranylation and mitochondrial depolarization. Perillic acid often locates in Membrane and Extracellular. The associated genes with Perillic acid are RAB3A gene and neutrophil cytosol factor 67K.
To understand associated biological information of Perillic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Perillic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Prostatic Neoplasms | D011471 | 126 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Perillic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Samaila D et al. | Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro. | 2004 Sep-Oct | Anticancer Res. | pmid:15517920 |
Bailey HH et al. | A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days. | 2004 | Cancer Chemother. Pharmacol. | pmid:15205914 |
Duetz WA et al. | Biotransformation of limonene by bacteria, fungi, yeasts, and plants. | 2003 | Appl. Microbiol. Biotechnol. | pmid:12743755 |
Beaupre DM et al. | Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells. | 2003 | Leuk. Lymphoma | pmid:14959858 |
Holstein SA and Hohl RJ | Monoterpene regulation of Ras and Ras-related protein expression. | 2003 | J. Lipid Res. | pmid:12671036 |
Azzoli CG et al. | A phase I trial of perillyl alcohol in patients with advanced solid tumors. | 2003 | Cancer Chemother. Pharmacol. | pmid:12695855 |
Choy WY et al. | Role of mitogen-activated protein kinase pathway in acetylcholine-mediated in vitro relaxation of rat pulmonary artery. | 2002 | Eur. J. Pharmacol. | pmid:11755166 |
Chow HH et al. | Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene content. | 2002 | Cancer Epidemiol. Biomarkers Prev. | pmid:12433729 |
Bardon S et al. | Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression. | 2002 | Cancer Lett. | pmid:12175534 |
Ferri N et al. | Effect of S(-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation. | 2001 | Biochem. Pharmacol. | pmid:11755117 |
Cheng QF et al. | Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. | 2001 | Exp. Eye Res. | pmid:11446774 |
Boon PJ et al. | Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10936079 |
Hudes GR et al. | Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies. | 2000 | Clin. Cancer Res. | pmid:10955786 |
Borsellino N et al. | Blocking signaling through the Gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity. | 1999 | Cancer | pmid:9921985 |
Hardcastle IR et al. | Inhibition of protein prenylation by metabolites of limonene. | 1999 | Biochem. Pharmacol. | pmid:10075086 |
Bardon S et al. | Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines. | 1998 | Nutr Cancer | pmid:9824849 |
Crance JM et al. | Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | 1997 Sep-Oct | Res. Virol. | pmid:9403935 |
Schulz S et al. | Perillic acid inhibits Ras/MAP kinase-driven IL-2 production in human T lymphocytes. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9434775 |
Ikechukwu Ezennia E et al. | Analysis of perillic acid in plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9061476 |
Luján HD et al. | Isoprenylation of proteins in the protozoan Giardia lamblia. | 1995 | Mol. Biochem. Parasitol. | pmid:8538683 |