Perillic acid

Perillic acid is a lipid of Prenol Lipids (PR) class. The involved functions are known as Membrane Potential, Mitochondrial, Neuroprotection, inhibitors, Protein Geranylgeranylation and mitochondrial depolarization. Perillic acid often locates in Membrane and Extracellular. The associated genes with Perillic acid are RAB3A gene and neutrophil cytosol factor 67K.

Cross Reference

Introduction

To understand associated biological information of Perillic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Perillic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Perillic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Perillic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Perillic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Perillic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Perillic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Perillic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Perillic acid

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Authors Title Published Journal PubMed Link
Choy WY et al. Role of mitogen-activated protein kinase pathway in acetylcholine-mediated in vitro relaxation of rat pulmonary artery. 2002 Eur. J. Pharmacol. pmid:11755166
Seto SW et al. Modulatory effect of interleukin-1beta on rat isolated basilar artery contraction. 2006 Eur. J. Pharmacol. pmid:16438962
Wu CS et al. Terpinen-4-ol Induces Apoptosis in Human Nonsmall Cell Lung Cancer In Vitro and In Vivo. 2012 Evid Based Complement Alternat Med pmid:21760828
Cheng QF et al. Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. 2001 Exp. Eye Res. pmid:11446774
Omoigui S The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. 2007 Immun Ageing pmid:17374166
Del Toro-Arreola S et al. Effect of D-limonene on immune response in BALB/c mice with lymphoma. 2005 Int. Immunopharmacol. pmid:15778119
Saldanha SN and Tollefsbol TO The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. 2012 J Oncol pmid:22187555
Ikechukwu Ezennia E et al. Analysis of perillic acid in plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9061476
Pratheeshkumar P et al. Protective role of perillic acid against radiation-induced oxidative stress, cytokine profile, DNA damage, and intestinal toxicity in mice. 2010 J. Environ. Pathol. Toxicol. Oncol. pmid:21303327
Mukherjee A et al. 6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis. 2010 J. Exp. Clin. Cancer Res. pmid:21194464