(+)-borneol

(+)-borneol is a lipid of Prenol Lipids (PR) class.

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Current reference collection contains 736 references associated with (+)-borneol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Yi T et al. Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies. 2017 Drug Deliv pmid:28165806
Yin Q et al. Influence of Temperature on Transdermal Penetration Enhancing Mechanism of Borneol: A Multi-Scale Study. 2017 Int J Mol Sci pmid:28106833
Tsang HL et al. Borneol Dehydrogenase from Pseudomonas sp. Strain TCU-HL1 Catalyzes the Oxidation of (+)-Borneol and Its Isomers to Camphor. 2016 Appl. Environ. Microbiol. pmid:27542933
Dai X et al. Effects of Concentrations on the Transdermal Permeation Enhancing Mechanisms of Borneol: A Coarse-Grained Molecular Dynamics Simulation on Mixed-Bilayer Membranes. 2016 Int J Mol Sci pmid:27548141
Xu X et al. A novel doxorubicin loaded folic acid conjugated PAMAM modified with borneol, a nature dual-functional product of reducing PAMAM toxicity and boosting BBB penetration. 2016 Eur J Pharm Sci pmid:26965003
Chen GL et al. Borneol Is a TRPM8 Agonist that Increases Ocular Surface Wetness. 2016 PLoS ONE pmid:27448228
Miyazawa M et al. Volatile Compounds with Characteristic Odor of Essential Oil from Magnolia obovata Leaves by Hydrodistillation and Solvent-assisted Flavor Evaporation. 2015 J Oleo Sci pmid:26250428
Fan X et al. Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model. 2015 Int J Mol Sci pmid:26593909
Zhang Q et al. Improved blood-brain barrier distribution: effect of borneol on the brain pharmacokinetics of kaempferol in rats by in vivo microdialysis sampling. 2015 J Ethnopharmacol pmid:25582491
Yin Q et al. Interactions of borneol with DPPC phospholipid membranes: a molecular dynamics simulation study. 2014 Int J Mol Sci pmid:25383679
Surendradoss J et al. Evaluation of in situ generated valproyl 1-O-β-acyl glucuronide in valproic acid toxicity in sandwich-cultured rat hepatocytes. 2014 Drug Metab. Dispos. pmid:25147275
Chen Z et al. Enhancing effect of borneol and muscone on geniposide transport across the human nasal epithelial cell monolayer. 2014 PLoS ONE pmid:24992195
Chen J et al. Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin. 2014 PLoS ONE pmid:24971451
Takaishi M et al. Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity. 2014 J Physiol Sci pmid:24122170
Machado M et al. Activity of Thymus capitellatus volatile extract, 1,8-cineole and borneol against Leishmania species. 2014 Vet. Parasitol. pmid:24365244
Wu C et al. Effect of natural borneol on the pharmacokinetics and distribution of nimodipine in mice. 2014 Eur J Drug Metab Pharmacokinet pmid:23673491
Jiang P et al. The effectiveness of borneol on pharmacokinetics changes of four ginsenosides in Shexiang Baoxin Pill in vivo. 2014 Biomed. Chromatogr. pmid:24123182
Xin HL et al. The effect of borneol on the concentration of meropenem in rat brain and blood. 2014 J Asian Nat Prod Res pmid:24827508
Xu P et al. Comparative pharmacokinetics of borneol in cerebral ischemia-reperfusion and sham-operated rats. 2014 J Zhejiang Univ Sci B pmid:24390748
Bruder S et al. Use of fuzzy logic models for prediction of taste and odor compounds in algal bloom-affected inland water bodies. 2014 Environ Monit Assess pmid:24242080
Xie XF et al. Chemical composition, antimicrobial and antioxidant activities of essential oil from Ampelopsis megalophylla. 2014 Nat. Prod. Res. pmid:24524337
Xu P et al. The effect of stroke and other components in Xing-Nao-Jing on the pharmacokinetics of geniposide. 2014 J Ethnopharmacol pmid:24412553
Kong QX et al. Study on the anti-cerebral ischemia effect of borneol and its mechanism. 2014 Afr J Tradit Complement Altern Med pmid:24653571
Ehrnhöfer-Ressler MM et al. Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts. 2013 J. Agric. Food Chem. pmid:23488631
Wei XH et al. Treatment with cardiotonic pills(®) after ischemia-reperfusion ameliorates myocardial fibrosis in rats. 2013 Microcirculation pmid:22913380
Yu B et al. Effects of borneol on the pharmacokinetics of geniposide in cortex, hippocampus, hypothalamus and striatum of conscious rat by simultaneous brain microdialysis coupled with UPLC-MS. 2013 J Pharm Biomed Anal pmid:23417086
Qi HP et al. In vitro evaluation of enhancing effect of borneol on transcorneal permeation of compounds with different hydrophilicities and molecular sizes. 2013 Eur. J. Pharmacol. pmid:23458068
Zhang L et al. The use of borneol as an enhancer for targeting aprotinin-conjugated PEG-PLGA nanoparticles to the brain. 2013 Pharm. Res. pmid:23615859
Hur J et al. Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells. 2013 Pharm Biol pmid:23134284
Zhang R et al. Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats. 2013 Eur J Drug Metab Pharmacokinet pmid:23589122
Almeida JR et al. Borneol, a bicyclic monoterpene alcohol, reduces nociceptive behavior and inflammatory response in mice. 2013 ScientificWorldJournal pmid:23710149
Song J et al. Natural borneol enhances geniposide ophthalmic absorption in rabbits. 2013 Int J Pharm pmid:23376228
Chen ZZ et al. Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model. 2013 Int J Pharm pmid:23973509
Chen J et al. Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel. 2013 Molecules pmid:24108402
Su J et al. Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage. 2013 PLoS ONE pmid:23700426
Cheng C et al. Sensitive assay for measurement of volatile borneol, isoborneol, and the metabolite camphor in rat pharmacokinetic study of Borneolum (Bingpian) and Borneolum syntheticum (synthetic Bingpian). 2013 Acta Pharmacol. Sin. pmid:23974515
Prasad B et al. Water oxidation by a cytochrome p450: mechanism and function of the reaction. 2013 PLoS ONE pmid:23634216
Su J et al. Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol. 2012 J. Food Sci. pmid:22583066
Ren-Zhong W et al. Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats. 2012 J Asian Nat Prod Res pmid:22587794
Horváthová E et al. Borneol administration protects primary rat hepatocytes against exogenous oxidative DNA damage. 2012 Mutagenesis pmid:22544524
El Babili F et al. Velamo do campo: its volatile constituents, secretory elements, and biological activity. 2012 J Med Food pmid:22612296
Lu Y et al. Bioavailability and brain-targeting of geniposide in gardenia-borneol co-compound by different administration routes in mice. 2012 Int J Mol Sci pmid:23203054
Li WR et al. Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio. 2012 Eur J Drug Metab Pharmacokinet pmid:21948240
Silva-Filho JC et al. Investigation of mechanisms involved in (-)-borneol-induced vasorelaxant response on rat thoracic aorta. 2012 Basic Clin. Pharmacol. Toxicol. pmid:21883938
Su J et al. Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse. 2012 Chem. Pharm. Bull. pmid:22689424
Zhao JY et al. Comparative pharmacokinetic studies of borneol in mouse plasma and brain by different administrations. 2012 J Zhejiang Univ Sci B pmid:23225854
Song X et al. In situ and in vivo study of nasal absorption of borneol in rats. 2012 Pharmazie pmid:23136719
Wang LS et al. Effect of Xiongbing compound on the pharmacokinetics and brain targeting of tetramethylpyrazine. 2012 J. Pharm. Pharmacol. pmid:23058057
Cherneva E et al. The effect of camphor and borneol on rat thymocyte viability and oxidative stress. 2012 Molecules pmid:22926306
Liu J et al. The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo. 2012 Eur. J. Pharmacol. pmid:22200629
Ceacero-Vega AA et al. Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). 2012 J Phys Chem A pmid:22448964
Missopolinou D et al. Selective extraction of oxygenated compounds from oregano with sub-critical water. 2012 J. Sci. Food Agric. pmid:22002497
Sarker LS et al. Molecular cloning and functional characterization of borneol dehydrogenase from the glandular trichomes of Lavandula x intermedia. 2012 Arch. Biochem. Biophys. pmid:23058847
Saravanakumar M et al. Molecular metabolic fingerprinting approach to investigate the effects of borneol on metabolic alterations in the liver of nitric oxide deficient hypertensive rats. 2012 Mol. Cell. Biochem. pmid:22045066
Shen Q et al. Enhanced intestinal absorption of daidzein by borneol/menthol eutectic mixture and microemulsion. 2011 AAPS PharmSciTech pmid:21842308
Xu X et al. Pharmacokinetic study of borneol and menthol in rats after oral administration of qingyan drop pills. 2011 Planta Med. pmid:21484670
Ait-Ouazzou A et al. Chemical composition and antimicrobial activity of essential oils of Thymus algeriensis, Eucalyptus globulus and Rosmarinus officinalis from Morocco. 2011 J. Sci. Food Agric. pmid:21769875
Okamoto S et al. A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet. 2011 FEBS J. pmid:21668645
Koga T et al. Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. 2011 Drug Metab. Dispos. pmid:20926620
Lu Y et al. Enhancing effect of natural borneol on the absorption of geniposide in rat via intranasal administration. 2011 J Zhejiang Univ Sci B pmid:21265046
Liu R et al. Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor κappaB signaling pathway. 2011 Neuroscience pmid:21168474
Lai XJ et al. Comparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in rats. 2011 Fitoterapia pmid:21575691
Prasad B et al. Identification of camphor oxidation and reduction products in Pseudomonas putida: new activity of the cytochrome P450cam system. 2011 J. Chem. Ecol. pmid:21562741
Jasinski P et al. MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis. 2011 Invest New Drugs pmid:20396929
Jin D et al. The distribution and expression of claudin-5 and occludin at the rat blood-optic nerve barrier after borneol treatment. 2011 Mol. Biol. Rep. pmid:20473716
He H et al. Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats. 2011 Arch. Pharm. Res. pmid:21811923
Neher TM et al. Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin. 2011 Mol. Cancer Ther. pmid:21846830
Polatoglu K et al. Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype. 2010 J Oleo Sci pmid:20484836
Gao C et al. Pharmacokinetic interaction between puerarin and edaravone, and effect of borneol on the brain distribution kinetics of puerarin in rats. 2010 J. Pharm. Pharmacol. pmid:20487220
Grillo MP et al. Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes. 2010 Drug Metab. Dispos. pmid:19786506
Kasashima Y et al. Amidation of alcohols with nitriles under solvent-free conditions using molecular iodine as a catalyst. 2010 J Oleo Sci pmid:20972361
Li Z et al. Effect of borneol on the distribution of danshensu to the eye in rabbit via oral administration. 2010 Curr. Eye Res. pmid:20597642
Chen XH et al. The orally combined neuroprotective effects of sodium ferulate and borneol against transient global ischaemia in C57 BL/6J mice. 2010 J. Pharm. Pharmacol. pmid:20636880
Lu Y et al. The in situ and in vivo study on enhancing effect of borneol in nasal absorption of Geniposide in rats. 2010 Arch. Pharm. Res. pmid:20512466
Yang H et al. Influence of borneol on in vitro corneal permeability and on in vivo and in vitro corneal toxicity. 2009 May-Jun J. Int. Med. Res. pmid:19589262
Slamenová D et al. Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines. 2009 Jun-Jul Mutat. Res. pmid:19501671
Mohsen H and Ali F Essential oil composition of Artemisia herba-alba from southern Tunisia. 2009 Molecules pmid:19384287
Dai JP et al. Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis. 2009 J. Oral Pathol. Med. pmid:19267840
Horváthová E et al. Effects of borneol on the level of DNA damage induced in primary rat hepatocytes and testicular cells by hydrogen peroxide. 2009 Food Chem. Toxicol. pmid:19285536
Peter A et al. Occurrence of dissolved and particle-bound taste and odor compounds in Swiss lake waters. 2009 Water Res. pmid:19303129
Morimoto M et al. Phytotoxicity of constituents of glandular trichomes and the leaf surface of camphorweed, Heterotheca subaxillaris. 2009 Phytochemistry pmid:19054533
Parnas M et al. Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. 2009 Cell Calcium pmid:19135721
Gangemi F et al. Experimental and ab-initio calculated vcd spectra of the first OH-stretching overtone of (1R)-(-) and (1S)-(+)-endo-BORNEOL. 2009 Phys Chem Chem Phys pmid:19421526
Frank D et al. Investigation of sensory and volatile characteristics of farmed and wild barramundi (Lates calcarifer) using gas chromatography-olfactometry mass spectrometry and descriptive sensory analysis. 2009 J. Agric. Food Chem. pmid:19824645
Abbate S et al. NIR-VCD, vibrational circular dichroism in the near-infrared: experiments, theory and calculations. 2009 Chirality pmid:19927373
Hu L and Chen DY Application of headspace solid phase microextraction for study of noncovalent interaction of borneol with human serum albumin. 2009 Acta Pharmacol. Sin. pmid:19890364
Juhás S et al. Effects of borneol and thymoquinone on TNBS-induced colitis in mice. 2008 Folia Biol. (Praha) pmid:18226358
Kim H et al. Identification and characterization of potent CYP2B6 inhibitors in Woohwangcheongsimwon suspension, an herbal preparation used in the treatment and prevention of apoplexy in Korea and China. 2008 Drug Metab. Dispos. pmid:18332082
Cai Z et al. Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration. 2008 J Drug Target pmid:18274938
Bhatia SP et al. Fragrance material review on borneol. 2008 Food Chem. Toxicol. pmid:18640181
Bhatia SP et al. Fragrance material review on l-borneol. 2008 Food Chem. Toxicol. pmid:18640204
Bhatia SP et al. Fragrance material review on isoborneol. 2008 Food Chem. Toxicol. pmid:18640231
Li YH et al. The antithrombotic effect of borneol related to its anticoagulant property. 2008 Am. J. Chin. Med. pmid:18711769
Grillo MP and Hua F Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes. 2008 Chem. Res. Toxicol. pmid:18680316
Kim YS et al. Inhibition of 7,12-dimethylbenz[a]anthracene induced mouse skin carcinogenesis by Artemisia capillaris. 2008 J. Food Sci. pmid:18211378
Yan-Yu X et al. The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse. 2007 Int J Pharm pmid:17275227
Sadeghi-Aliabadi H et al. Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. 2007 Chem. Biol. Interact. pmid:17408604
Serena T et al. Bismuth subgallate/borneol (suile) is superior to bacitracin in the human forearm biopsy model for acute wound healing. 2007 Adv Skin Wound Care pmid:17762217
Liu Y et al. Spectrophotometric and calorimetric titration studies on molecular recognition of camphor and borneol by nucleobase-modified beta-cyclodextrins. 2007 J Phys Chem B pmid:17914791
Tian LL et al. Protective effect of (+/-) isoborneol against 6-OHDA-induced apoptosis in SH-SY5Y cells. 2007 Cell. Physiol. Biochem. pmid:17975304

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