| MeSH term | MeSH ID | Detail |
|---|---|---|
| Back Injuries | D019567 | 1 associated lipids |
| Oral Submucous Fibrosis | D009914 | 1 associated lipids |
| Otitis Media, Suppurative | D010035 | 4 associated lipids |
| Lymphatic Metastasis | D008207 | 10 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Ventricular Remodeling | D020257 | 28 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Peritonitis | D010538 | 38 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
(-)-Borneol
(-)-borneol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Protein-Protein Interaction.
Cross Reference
Introduction
To understand associated biological information of (-)-Borneol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Borneol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Borneol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
What functions are associated with (-)-Borneol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
What genes are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Borneol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yi T et al. | Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies. | 2017 | Drug Deliv | pmid:28165806 |
| Yin Q et al. | Influence of Temperature on Transdermal Penetration Enhancing Mechanism of Borneol: A Multi-Scale Study. | 2017 | Int J Mol Sci | pmid:28106833 |
| Tsang HL et al. | Borneol Dehydrogenase from Pseudomonas sp. Strain TCU-HL1 Catalyzes the Oxidation of (+)-Borneol and Its Isomers to Camphor. | 2016 | Appl. Environ. Microbiol. | pmid:27542933 |
| Dai X et al. | Effects of Concentrations on the Transdermal Permeation Enhancing Mechanisms of Borneol: A Coarse-Grained Molecular Dynamics Simulation on Mixed-Bilayer Membranes. | 2016 | Int J Mol Sci | pmid:27548141 |
| Xu X et al. | A novel doxorubicin loaded folic acid conjugated PAMAM modified with borneol, a nature dual-functional product of reducing PAMAM toxicity and boosting BBB penetration. | 2016 | Eur J Pharm Sci | pmid:26965003 |
| Chen GL et al. | Borneol Is a TRPM8 Agonist that Increases Ocular Surface Wetness. | 2016 | PLoS ONE | pmid:27448228 |
| Miyazawa M et al. | Volatile Compounds with Characteristic Odor of Essential Oil from Magnolia obovata Leaves by Hydrodistillation and Solvent-assisted Flavor Evaporation. | 2015 | J Oleo Sci | pmid:26250428 |
| Fan X et al. | Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model. | 2015 | Int J Mol Sci | pmid:26593909 |
| Zhang Q et al. | Improved blood-brain barrier distribution: effect of borneol on the brain pharmacokinetics of kaempferol in rats by in vivo microdialysis sampling. | 2015 | J Ethnopharmacol | pmid:25582491 |
| Yin Q et al. | Interactions of borneol with DPPC phospholipid membranes: a molecular dynamics simulation study. | 2014 | Int J Mol Sci | pmid:25383679 |
| Surendradoss J et al. | Evaluation of in situ generated valproyl 1-O-β-acyl glucuronide in valproic acid toxicity in sandwich-cultured rat hepatocytes. | 2014 | Drug Metab. Dispos. | pmid:25147275 |
| Chen Z et al. | Enhancing effect of borneol and muscone on geniposide transport across the human nasal epithelial cell monolayer. | 2014 | PLoS ONE | pmid:24992195 |
| Chen J et al. | Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin. | 2014 | PLoS ONE | pmid:24971451 |
| Takaishi M et al. | Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity. | 2014 | J Physiol Sci | pmid:24122170 |
| Machado M et al. | Activity of Thymus capitellatus volatile extract, 1,8-cineole and borneol against Leishmania species. | 2014 | Vet. Parasitol. | pmid:24365244 |
| Wu C et al. | Effect of natural borneol on the pharmacokinetics and distribution of nimodipine in mice. | 2014 | Eur J Drug Metab Pharmacokinet | pmid:23673491 |
| Jiang P et al. | The effectiveness of borneol on pharmacokinetics changes of four ginsenosides in Shexiang Baoxin Pill in vivo. | 2014 | Biomed. Chromatogr. | pmid:24123182 |
| Xin HL et al. | The effect of borneol on the concentration of meropenem in rat brain and blood. | 2014 | J Asian Nat Prod Res | pmid:24827508 |
| Xu P et al. | Comparative pharmacokinetics of borneol in cerebral ischemia-reperfusion and sham-operated rats. | 2014 | J Zhejiang Univ Sci B | pmid:24390748 |
| Bruder S et al. | Use of fuzzy logic models for prediction of taste and odor compounds in algal bloom-affected inland water bodies. | 2014 | Environ Monit Assess | pmid:24242080 |
| Xie XF et al. | Chemical composition, antimicrobial and antioxidant activities of essential oil from Ampelopsis megalophylla. | 2014 | Nat. Prod. Res. | pmid:24524337 |
| Xu P et al. | The effect of stroke and other components in Xing-Nao-Jing on the pharmacokinetics of geniposide. | 2014 | J Ethnopharmacol | pmid:24412553 |
| Kong QX et al. | Study on the anti-cerebral ischemia effect of borneol and its mechanism. | 2014 | Afr J Tradit Complement Altern Med | pmid:24653571 |
| Ehrnhöfer-Ressler MM et al. | Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts. | 2013 | J. Agric. Food Chem. | pmid:23488631 |
| Wei XH et al. | Treatment with cardiotonic pills(®) after ischemia-reperfusion ameliorates myocardial fibrosis in rats. | 2013 | Microcirculation | pmid:22913380 |
| Yu B et al. | Effects of borneol on the pharmacokinetics of geniposide in cortex, hippocampus, hypothalamus and striatum of conscious rat by simultaneous brain microdialysis coupled with UPLC-MS. | 2013 | J Pharm Biomed Anal | pmid:23417086 |
| Qi HP et al. | In vitro evaluation of enhancing effect of borneol on transcorneal permeation of compounds with different hydrophilicities and molecular sizes. | 2013 | Eur. J. Pharmacol. | pmid:23458068 |
| Zhang L et al. | The use of borneol as an enhancer for targeting aprotinin-conjugated PEG-PLGA nanoparticles to the brain. | 2013 | Pharm. Res. | pmid:23615859 |
| Hur J et al. | Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells. | 2013 | Pharm Biol | pmid:23134284 |
| Zhang R et al. | Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats. | 2013 | Eur J Drug Metab Pharmacokinet | pmid:23589122 |
| Almeida JR et al. | Borneol, a bicyclic monoterpene alcohol, reduces nociceptive behavior and inflammatory response in mice. | 2013 | ScientificWorldJournal | pmid:23710149 |
| Xiong ZY et al. | [Studies on pharmacological activity of borneol]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23717952 |
| Song J et al. | Natural borneol enhances geniposide ophthalmic absorption in rabbits. | 2013 | Int J Pharm | pmid:23376228 |
| Chen ZZ et al. | Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model. | 2013 | Int J Pharm | pmid:23973509 |
| Chen J et al. | Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel. | 2013 | Molecules | pmid:24108402 |
| Su J et al. | Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage. | 2013 | PLoS ONE | pmid:23700426 |
| Xu P et al. | [Comparative pharmacokinetic studies of borneol in brain and plasma of stroke or sham-operated rats after administration of Xingnaojing]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:24494569 |
| Yu B et al. | The mechanism of the opening of the blood-brain barrier by borneol: a pharmacodynamics and pharmacokinetics combination study. | 2013 | J Ethnopharmacol | pmid:24432371 |
| Cheng C et al. | Sensitive assay for measurement of volatile borneol, isoborneol, and the metabolite camphor in rat pharmacokinetic study of Borneolum (Bingpian) and Borneolum syntheticum (synthetic Bingpian). | 2013 | Acta Pharmacol. Sin. | pmid:23974515 |
| Prasad B et al. | Water oxidation by a cytochrome p450: mechanism and function of the reaction. | 2013 | PLoS ONE | pmid:23634216 |
| Vasconcelos RM et al. | Synthesis, acute toxicity and anti-inflammatory effect of bornyl salicylate, a salicylic acid derivative. | 2012 | Immunopharmacol Immunotoxicol | pmid:22712758 |
| Su J et al. | Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol. | 2012 | J. Food Sci. | pmid:22583066 |
| Ren-Zhong W et al. | Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats. | 2012 | J Asian Nat Prod Res | pmid:22587794 |
| Horváthová E et al. | Borneol administration protects primary rat hepatocytes against exogenous oxidative DNA damage. | 2012 | Mutagenesis | pmid:22544524 |
| El Babili F et al. | Velamo do campo: its volatile constituents, secretory elements, and biological activity. | 2012 | J Med Food | pmid:22612296 |
| Lu Y et al. | Bioavailability and brain-targeting of geniposide in gardenia-borneol co-compound by different administration routes in mice. | 2012 | Int J Mol Sci | pmid:23203054 |
| Li WR et al. | Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:21948240 |
| Silva-Filho JC et al. | Investigation of mechanisms involved in (-)-borneol-induced vasorelaxant response on rat thoracic aorta. | 2012 | Basic Clin. Pharmacol. Toxicol. | pmid:21883938 |
| Lv X et al. | [Research of bornrol promote drugs through blood-brain barrier]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22792780 |
| Gao ZS et al. | [Effects of penetration enhancers on curcumin transdermal drug delivery]. | 2012 | Zhong Yao Cai | pmid:22734426 |
| Su J et al. | Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse. | 2012 | Chem. Pharm. Bull. | pmid:22689424 |
| Zhao JY et al. | Comparative pharmacokinetic studies of borneol in mouse plasma and brain by different administrations. | 2012 | J Zhejiang Univ Sci B | pmid:23225854 |
| Zou L et al. | [Effect of borneol on intestinal absorption of muscone in rats]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23373228 |
| Song X et al. | In situ and in vivo study of nasal absorption of borneol in rats. | 2012 | Pharmazie | pmid:23136719 |
| Wang LS et al. | Effect of Xiongbing compound on the pharmacokinetics and brain targeting of tetramethylpyrazine. | 2012 | J. Pharm. Pharmacol. | pmid:23058057 |
| Cherneva E et al. | The effect of camphor and borneol on rat thymocyte viability and oxidative stress. | 2012 | Molecules | pmid:22926306 |
| Liu J et al. | The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo. | 2012 | Eur. J. Pharmacol. | pmid:22200629 |
| Ceacero-Vega AA et al. | Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). | 2012 | J Phys Chem A | pmid:22448964 |
| Missopolinou D et al. | Selective extraction of oxygenated compounds from oregano with sub-critical water. | 2012 | J. Sci. Food Agric. | pmid:22002497 |
| Sarker LS et al. | Molecular cloning and functional characterization of borneol dehydrogenase from the glandular trichomes of Lavandula x intermedia. | 2012 | Arch. Biochem. Biophys. | pmid:23058847 |
| Saravanakumar M et al. | Molecular metabolic fingerprinting approach to investigate the effects of borneol on metabolic alterations in the liver of nitric oxide deficient hypertensive rats. | 2012 | Mol. Cell. Biochem. | pmid:22045066 |
| Song X et al. | [Study on rat nasal absorption in situ of borneol based on single pass perfusion method]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22256751 |
| Ni C et al. | [Effects of aromatic resuscitation drugs on blood brain barrier in cerebral ischemia-reperfusion injury model rats]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22256767 |
| Zhang N et al. | [Effect of single-used borneol and combining it with diazepam on content of neurotransmitter in corpus striatum of rats]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22375403 |
| Chen M et al. | [Volatile metabolites analysis and molecular identification of endophytic fungi bn12 from Cinnamomum camphora chvar. borneol]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22393723 |
| Shen Q et al. | Enhanced intestinal absorption of daidzein by borneol/menthol eutectic mixture and microemulsion. | 2011 | AAPS PharmSciTech | pmid:21842308 |
| de Boer HJ et al. | Steam sauna and mother roasting in Lao PDR: practices and chemical constituents of essential oils of plant species used in postpartum recovery. | 2011 | BMC Complement Altern Med | pmid:22171719 |
| Xu X et al. | Pharmacokinetic study of borneol and menthol in rats after oral administration of qingyan drop pills. | 2011 | Planta Med. | pmid:21484670 |
| Ait-Ouazzou A et al. | Chemical composition and antimicrobial activity of essential oils of Thymus algeriensis, Eucalyptus globulus and Rosmarinus officinalis from Morocco. | 2011 | J. Sci. Food Agric. | pmid:21769875 |
| Okamoto S et al. | A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet. | 2011 | FEBS J. | pmid:21668645 |
| Koga T et al. | Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. | 2011 | Drug Metab. Dispos. | pmid:20926620 |
| Lu Y et al. | Enhancing effect of natural borneol on the absorption of geniposide in rat via intranasal administration. | 2011 | J Zhejiang Univ Sci B | pmid:21265046 |
| Liu R et al. | Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor κappaB signaling pathway. | 2011 | Neuroscience | pmid:21168474 |
| Lai XJ et al. | Comparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in rats. | 2011 | Fitoterapia | pmid:21575691 |
| Prasad B et al. | Identification of camphor oxidation and reduction products in Pseudomonas putida: new activity of the cytochrome P450cam system. | 2011 | J. Chem. Ecol. | pmid:21562741 |
| Jasinski P et al. | MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis. | 2011 | Invest New Drugs | pmid:20396929 |
| Jin D et al. | The distribution and expression of claudin-5 and occludin at the rat blood-optic nerve barrier after borneol treatment. | 2011 | Mol. Biol. Rep. | pmid:20473716 |
| Lu Y et al. | [Study on pharmacokinetics of borneol in rats injected with novel-xingnaojing by GC-FID]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22097329 |
| Yu B et al. | [Effect of electroacupuncture combined with intragastric administration of borneol on the permeability of blood-brain barrier in the mouse]. | 2011 | Zhen Ci Yan Jiu | pmid:22073884 |
| He H et al. | Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats. | 2011 | Arch. Pharm. Res. | pmid:21811923 |
| Neher TM et al. | Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin. | 2011 | Mol. Cancer Ther. | pmid:21846830 |
| Polatoglu K et al. | Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype. | 2010 | J Oleo Sci | pmid:20484836 |
| Gao C et al. | Pharmacokinetic interaction between puerarin and edaravone, and effect of borneol on the brain distribution kinetics of puerarin in rats. | 2010 | J. Pharm. Pharmacol. | pmid:20487220 |
| Grillo MP et al. | Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes. | 2010 | Drug Metab. Dispos. | pmid:19786506 |
| Kasashima Y et al. | Amidation of alcohols with nitriles under solvent-free conditions using molecular iodine as a catalyst. | 2010 | J Oleo Sci | pmid:20972361 |
| Wei Y et al. | [Microdialysis and HPLC method for determination of concentration of pantoprazole in rat striatum aftercombined administration with borneol]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:21174774 |
| Qin X et al. | Oral characteristics of bergenin and the effect of absorption enhancers in situ, in vitro and in vivo. | 2010 | Arzneimittelforschung | pmid:20486470 |
| Li Z et al. | Effect of borneol on the distribution of danshensu to the eye in rabbit via oral administration. | 2010 | Curr. Eye Res. | pmid:20597642 |
| Chen XH et al. | The orally combined neuroprotective effects of sodium ferulate and borneol against transient global ischaemia in C57 BL/6J mice. | 2010 | J. Pharm. Pharmacol. | pmid:20636880 |
| Chen M et al. | [Callus induction of Cinnamonum camphora and formation of borneol]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:20506810 |
| Lu Y et al. | The in situ and in vivo study on enhancing effect of borneol in nasal absorption of Geniposide in rats. | 2010 | Arch. Pharm. Res. | pmid:20512466 |
| Lai XJ et al. | [Intestinal absorption properties of three components in salvianolic acid extract and the effect of borneol on their absorption in rats]. | 2010 | Yao Xue Xue Bao | pmid:21351500 |
| Yang H et al. | Influence of borneol on in vitro corneal permeability and on in vivo and in vitro corneal toxicity. | 2009 May-Jun | J. Int. Med. Res. | pmid:19589262 |
| Slamenová D et al. | Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines. | 2009 Jun-Jul | Mutat. Res. | pmid:19501671 |
| Mohsen H and Ali F | Essential oil composition of Artemisia herba-alba from southern Tunisia. | 2009 | Molecules | pmid:19384287 |
| Dai JP et al. | Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis. | 2009 | J. Oral Pathol. Med. | pmid:19267840 |
| Horváthová E et al. | Effects of borneol on the level of DNA damage induced in primary rat hepatocytes and testicular cells by hydrogen peroxide. | 2009 | Food Chem. Toxicol. | pmid:19285536 |
| Peter A et al. | Occurrence of dissolved and particle-bound taste and odor compounds in Swiss lake waters. | 2009 | Water Res. | pmid:19303129 |
| Parnas M et al. | Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. | 2009 | Cell Calcium | pmid:19135721 |
| Xiao YY et al. | [The enhancing effect of borneol on the absorption of tetramethylpyrazine]. | 2009 | Yao Xue Xue Bao | pmid:20055162 |