| MeSH term | MeSH ID | Detail |
|---|---|---|
| Otitis Media, Suppurative | D010035 | 4 associated lipids |
| Peritonitis | D010538 | 38 associated lipids |
| Back Injuries | D019567 | 1 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Ventricular Remodeling | D020257 | 28 associated lipids |
| Stroke | D020521 | 32 associated lipids |
(-)-Borneol
(-)-borneol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Protein-Protein Interaction.
Cross Reference
Introduction
To understand associated biological information of (-)-Borneol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Borneol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Borneol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
What functions are associated with (-)-Borneol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
What genes are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with (-)-Borneol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Borneol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tamura S and Matsumoto Y | Comparative studies on postnatal development of liver beta-glucuronidase activity between Gunn rats and Wistar rats. | 1980 | J Toxicol Sci | pmid:7218379 |
| Takaishi M et al. | Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity. | 2014 | J Physiol Sci | pmid:24122170 |
| Liu Y et al. | Spectrophotometric and calorimetric titration studies on molecular recognition of camphor and borneol by nucleobase-modified beta-cyclodextrins. | 2007 | J Phys Chem B | pmid:17914791 |
| Ceacero-Vega AA et al. | Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). | 2012 | J Phys Chem A | pmid:22448964 |
| Yu B et al. | Effects of borneol on the pharmacokinetics of geniposide in cortex, hippocampus, hypothalamus and striatum of conscious rat by simultaneous brain microdialysis coupled with UPLC-MS. | 2013 | J Pharm Biomed Anal | pmid:23417086 |
| Miyazawa M et al. | Volatile Compounds with Characteristic Odor of Essential Oil from Magnolia obovata Leaves by Hydrodistillation and Solvent-assisted Flavor Evaporation. | 2015 | J Oleo Sci | pmid:26250428 |
| Polatoglu K et al. | Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype. | 2010 | J Oleo Sci | pmid:20484836 |
| Kasashima Y et al. | Amidation of alcohols with nitriles under solvent-free conditions using molecular iodine as a catalyst. | 2010 | J Oleo Sci | pmid:20972361 |
| El Babili F et al. | Velamo do campo: its volatile constituents, secretory elements, and biological activity. | 2012 | J Med Food | pmid:22612296 |
| Yu B et al. | The mechanism of the opening of the blood-brain barrier by borneol: a pharmacodynamics and pharmacokinetics combination study. | 2013 | J Ethnopharmacol | pmid:24432371 |
| Xu P et al. | The effect of stroke and other components in Xing-Nao-Jing on the pharmacokinetics of geniposide. | 2014 | J Ethnopharmacol | pmid:24412553 |
| Zhang Q et al. | Improved blood-brain barrier distribution: effect of borneol on the brain pharmacokinetics of kaempferol in rats by in vivo microdialysis sampling. | 2015 | J Ethnopharmacol | pmid:25582491 |
| Cai Z et al. | Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration. | 2008 | J Drug Target | pmid:18274938 |
| Yan-Yu X et al. | A simple gas chromatographic method for the simultaneous determination and pharmacokinetic study of tetramethylpyrazine phosphate and borneol in mouse plasma and brain tissue after oral administration of the fufang tetramethylpyrazine phosphate tablets. | 2008 May-Jun | J Chromatogr Sci | pmid:18492348 |
| Zhang R et al. | In vitro characterization of borneol metabolites by GC-MS upon incubation with rat liver microsomes. | 2008 May-Jun | J Chromatogr Sci | pmid:18492352 |
| Ren-Zhong W et al. | Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats. | 2012 | J Asian Nat Prod Res | pmid:22587794 |
| Xin HL et al. | The effect of borneol on the concentration of meropenem in rat brain and blood. | 2014 | J Asian Nat Prod Res | pmid:24827508 |
| Jasinski P et al. | MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis. | 2011 | Invest New Drugs | pmid:20396929 |
| Yan-Yu X et al. | The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse. | 2007 | Int J Pharm | pmid:17275227 |
| Song J et al. | Natural borneol enhances geniposide ophthalmic absorption in rabbits. | 2013 | Int J Pharm | pmid:23376228 |
| Chen ZZ et al. | Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model. | 2013 | Int J Pharm | pmid:23973509 |
| Yin Q et al. | Influence of Temperature on Transdermal Penetration Enhancing Mechanism of Borneol: A Multi-Scale Study. | 2017 | Int J Mol Sci | pmid:28106833 |
| Dai X et al. | Effects of Concentrations on the Transdermal Permeation Enhancing Mechanisms of Borneol: A Coarse-Grained Molecular Dynamics Simulation on Mixed-Bilayer Membranes. | 2016 | Int J Mol Sci | pmid:27548141 |
| Fan X et al. | Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model. | 2015 | Int J Mol Sci | pmid:26593909 |
| Yin Q et al. | Interactions of borneol with DPPC phospholipid membranes: a molecular dynamics simulation study. | 2014 | Int J Mol Sci | pmid:25383679 |
| Lu Y et al. | Bioavailability and brain-targeting of geniposide in gardenia-borneol co-compound by different administration routes in mice. | 2012 | Int J Mol Sci | pmid:23203054 |
| Vasconcelos RM et al. | Synthesis, acute toxicity and anti-inflammatory effect of bornyl salicylate, a salicylic acid derivative. | 2012 | Immunopharmacol Immunotoxicol | pmid:22712758 |
| Wu CY et al. | [Preparative separation of borneol and isoborneol in bingpian by dry-column chromatography]. | 1989 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:2625343 |
| Gu XY et al. | [Measurement of borneol based on near infrared spectroscopy]. | 2004 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:15769004 |
| Ni LJ et al. | [Near infrared spectrometry (NIRS) method for the determination of borneol in sustained-release drugs]. | 2006 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:16827347 |
| Tong V et al. | Valproic acid glucuronidation is associated with increases in 15-F2t-isoprostane in rats. | 2005 | Free Radic. Biol. Med. | pmid:15890621 |
| Bhatia SP et al. | Fragrance material review on borneol. | 2008 | Food Chem. Toxicol. | pmid:18640181 |
| Bhatia SP et al. | Fragrance material review on l-borneol. | 2008 | Food Chem. Toxicol. | pmid:18640204 |
| Bhatia SP et al. | Fragrance material review on isoborneol. | 2008 | Food Chem. Toxicol. | pmid:18640231 |
| Horváthová E et al. | Effects of borneol on the level of DNA damage induced in primary rat hepatocytes and testicular cells by hydrogen peroxide. | 2009 | Food Chem. Toxicol. | pmid:19285536 |
| Juhás S et al. | Effects of borneol and thymoquinone on TNBS-induced colitis in mice. | 2008 | Folia Biol. (Praha) | pmid:18226358 |
| Lai XJ et al. | Comparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in rats. | 2011 | Fitoterapia | pmid:21575691 |
| Okamoto S et al. | A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet. | 2011 | FEBS J. | pmid:21668645 |
| Qi HP et al. | In vitro evaluation of enhancing effect of borneol on transcorneal permeation of compounds with different hydrophilicities and molecular sizes. | 2013 | Eur. J. Pharmacol. | pmid:23458068 |
| Liu J et al. | The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo. | 2012 | Eur. J. Pharmacol. | pmid:22200629 |
| Xu X et al. | A novel doxorubicin loaded folic acid conjugated PAMAM modified with borneol, a nature dual-functional product of reducing PAMAM toxicity and boosting BBB penetration. | 2016 | Eur J Pharm Sci | pmid:26965003 |
| Li WR et al. | Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:21948240 |
| Wu C et al. | Effect of natural borneol on the pharmacokinetics and distribution of nimodipine in mice. | 2014 | Eur J Drug Metab Pharmacokinet | pmid:23673491 |
| Zhang R et al. | Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats. | 2013 | Eur J Drug Metab Pharmacokinet | pmid:23589122 |
| Bruder S et al. | Use of fuzzy logic models for prediction of taste and odor compounds in algal bloom-affected inland water bodies. | 2014 | Environ Monit Assess | pmid:24242080 |
| Kim H et al. | Identification and characterization of potent CYP2B6 inhibitors in Woohwangcheongsimwon suspension, an herbal preparation used in the treatment and prevention of apoplexy in Korea and China. | 2008 | Drug Metab. Dispos. | pmid:18332082 |
| Surendradoss J et al. | Evaluation of in situ generated valproyl 1-O-β-acyl glucuronide in valproic acid toxicity in sandwich-cultured rat hepatocytes. | 2014 | Drug Metab. Dispos. | pmid:25147275 |
| Grillo MP et al. | Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes. | 2010 | Drug Metab. Dispos. | pmid:19786506 |
| Koga T et al. | Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. | 2011 | Drug Metab. Dispos. | pmid:20926620 |
| Yi T et al. | Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies. | 2017 | Drug Deliv | pmid:28165806 |
| Li Z et al. | Effect of borneol on the distribution of danshensu to the eye in rabbit via oral administration. | 2010 | Curr. Eye Res. | pmid:20597642 |
| Abbate S et al. | NIR-VCD, vibrational circular dichroism in the near-infrared: experiments, theory and calculations. | 2009 | Chirality | pmid:19927373 |
| Grillo MP and Hua F | Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes. | 2008 | Chem. Res. Toxicol. | pmid:18680316 |
| Grillo MP et al. | Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes. | 2003 | Chem. Res. Toxicol. | pmid:14615966 |
| Li C et al. | Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes. | 2002 | Chem. Res. Toxicol. | pmid:12437340 |
| Su J et al. | Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse. | 2012 | Chem. Pharm. Bull. | pmid:22689424 |
| Sadeghi-Aliabadi H et al. | Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. | 2007 | Chem. Biol. Interact. | pmid:17408604 |
| Siraki AG et al. | Application of quantitative structure-toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes. | 2005 | Chem. Biol. Interact. | pmid:15733539 |
| Ghaoui R et al. | UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes. | 2003 | Chem. Biol. Interact. | pmid:12686496 |
| Tian LL et al. | Protective effect of (+/-) isoborneol against 6-OHDA-induced apoptosis in SH-SY5Y cells. | 2007 | Cell. Physiol. Biochem. | pmid:17975304 |
| Parnas M et al. | Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. | 2009 | Cell Calcium | pmid:19135721 |
| DEYSSON G and EDOUARD P | [Not Available]. | 1949 | C. R. Hebd. Seances Acad. Sci. | pmid:15408697 |
| de Boer HJ et al. | Steam sauna and mother roasting in Lao PDR: practices and chemical constituents of essential oils of plant species used in postpartum recovery. | 2011 | BMC Complement Altern Med | pmid:22171719 |
| Klar U et al. | New synthetic inhibitors of microtubule depolymerization. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871773 |
| Jiang P et al. | The effectiveness of borneol on pharmacokinetics changes of four ginsenosides in Shexiang Baoxin Pill in vivo. | 2014 | Biomed. Chromatogr. | pmid:24123182 |
| Mai LM et al. | Synergistic effect of bismuth subgallate and borneol, the major components of Sulbogin, on the healing of skin wound. | 2003 | Biomaterials | pmid:12895572 |
| Helms V et al. | Improved binding of cytochrome P450cam substrate analogues designed to fill extra space in the substrate binding pocket. | 1996 | Biochemistry | pmid:8634279 |
| Granger RE et al. | (+)- And (-)-borneol: efficacious positive modulators of GABA action at human recombinant alpha1beta2gamma2L GABA(A) receptors. | 2005 | Biochem. Pharmacol. | pmid:15763546 |
| Park TJ et al. | Inhibition of acetylcholine-mediated effects by borneol. | 2003 | Biochem. Pharmacol. | pmid:12473382 |
| Boutin JA et al. | UDP-glucuronosyltransferase activities in human liver microsomes and in some laboratory animal species. | 1981 | Biochem. Pharmacol. | pmid:21043258 |
| Silva-Filho JC et al. | Investigation of mechanisms involved in (-)-borneol-induced vasorelaxant response on rat thoracic aorta. | 2012 | Basic Clin. Pharmacol. Toxicol. | pmid:21883938 |
| Qin X et al. | Oral characteristics of bergenin and the effect of absorption enhancers in situ, in vitro and in vivo. | 2010 | Arzneimittelforschung | pmid:20486470 |
| Lu Y et al. | The in situ and in vivo study on enhancing effect of borneol in nasal absorption of Geniposide in rats. | 2010 | Arch. Pharm. Res. | pmid:20512466 |
| He H et al. | Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats. | 2011 | Arch. Pharm. Res. | pmid:21811923 |
| Sarker LS et al. | Molecular cloning and functional characterization of borneol dehydrogenase from the glandular trichomes of Lavandula x intermedia. | 2012 | Arch. Biochem. Biophys. | pmid:23058847 |
| van den Hurk P | Bile fluorescence, heme oxygenase induction, and increased biliverdin excretion by mixtures of environmental toxicants. | 2006 | Aquat. Toxicol. | pmid:16426685 |
| Tsang HL et al. | Borneol Dehydrogenase from Pseudomonas sp. Strain TCU-HL1 Catalyzes the Oxidation of (+)-Borneol and Its Isomers to Camphor. | 2016 | Appl. Environ. Microbiol. | pmid:27542933 |
| Guo C et al. | Enantiomeric excess determination by fourier transform near-infrared vibrational circular dichroism spectroscopy: simulation of real-time process monitoring. | 2005 | Appl Spectrosc | pmid:16197634 |
| Frisvad JC et al. | Penicillium discolor, a new species from cheese, nuts and vegetables. | 1997 | Antonie Van Leeuwenhoek | pmid:9298190 |
| Armaka M et al. | Antiviral properties of isoborneol, a potent inhibitor of herpes simplex virus type 1. | 1999 | Antiviral Res. | pmid:10517310 |
| Guo C et al. | Determination of enantiomeric excess in samples of chiral molecules using fourier transform vibrational circular dichroism spectroscopy: simulation of real-time reaction monitoring. | 2004 | Anal. Chem. | pmid:15571347 |
| Makabe A et al. | Guest-responsive fluorescence variations of gamma-cyclodextrins labeled with hetero-functionalized pyrene and tosyl moieties. | 2002 | Anal Sci | pmid:11874110 |
| Li YH et al. | The antithrombotic effect of borneol related to its anticoagulant property. | 2008 | Am. J. Chin. Med. | pmid:18711769 |
| Kong QX et al. | Study on the anti-cerebral ischemia effect of borneol and its mechanism. | 2014 | Afr J Tradit Complement Altern Med | pmid:24653571 |
| Serena T et al. | Bismuth subgallate/borneol (suile) is superior to bacitracin in the human forearm biopsy model for acute wound healing. | 2007 | Adv Skin Wound Care | pmid:17762217 |
| Cheng C et al. | Sensitive assay for measurement of volatile borneol, isoborneol, and the metabolite camphor in rat pharmacokinetic study of Borneolum (Bingpian) and Borneolum syntheticum (synthetic Bingpian). | 2013 | Acta Pharmacol. Sin. | pmid:23974515 |
| Hu L and Chen DY | Application of headspace solid phase microextraction for study of noncovalent interaction of borneol with human serum albumin. | 2009 | Acta Pharmacol. Sin. | pmid:19890364 |
| Shen Q et al. | Enhanced intestinal absorption of daidzein by borneol/menthol eutectic mixture and microemulsion. | 2011 | AAPS PharmSciTech | pmid:21842308 |
| pmid:23625080 | ||||
| pmid: | ||||
| pmid:25652583 | ||||
| pmid:26508078 | ||||
| pmid:26291250 | ||||
| pmid:26051007 | ||||
| pmid:25891382 | ||||
| pmid:25890088 | ||||
| pmid:25835611 | ||||
| pmid:25537301 | ||||
| pmid:19826737 | ||||
| pmid:22805939 |