MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Seizures | D012640 | 87 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thujone
MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Seizures | D012640 | 87 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Albert-Puleo M | Van Gogh's vision: thujone intoxication. | 1981 | JAMA | pmid:7017175 |
Dettling A et al. | Absinthe: attention performance and mood under the influence of thujone. | 2004 | J. Stud. Alcohol | pmid:15536765 |
Grausgruber-Gröger S et al. | Seasonal influence on gene expression of monoterpene synthases in Salvia officinalis (Lamiaceae). | 2012 | J. Plant Physiol. | pmid:22196947 |
Schmiderer C et al. | Influence of gibberellin and daminozide on the expression of terpene synthases and on monoterpenes in common sage (Salvia officinalis). | 2010 | J. Plant Physiol. | pmid:20163890 |
He X and Ortiz de Montellano PR | Alpha- and beta-thujone radical rearrangements and isomerizations. A new radical clock. | 2004 | J. Org. Chem. | pmid:15307740 |
Monroe RR | Another diagnosis for Vincent Van Gogh? | 1991 | J. Nerv. Ment. Dis. | pmid:2007896 |
Szczot M et al. | Modulation of GABAergic synaptic currents and current responses by α-thujone and dihydroumbellulone. | 2012 | J. Nat. Prod. | pmid:22364543 |
Cha JD et al. | Chemical composition and antibacterial activity of essential oil from Artemisia feddei. | 2007 | J. Microbiol. Biotechnol. | pmid:18167456 |
Sõukand R et al. | Uninvited guests: traditional insect repellents in Estonia used against the clothes moth Tineola bisselliella, human flea Pulex irritons and bedbug Cimex lectularius. | 2010 | J. Insect Sci. | pmid:21070174 |
He X and de Montellano PR | Radical rebound mechanism in cytochrome P-450-catalyzed hydroxylation of the multifaceted radical clocks alpha- and beta-thujone. | 2004 | J. Biol. Chem. | pmid:15258138 |