Thujone

Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.

Cross Reference

Introduction

To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thujone?

Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thujone

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Seizures D012640 87 associated lipids
Insulin Resistance D007333 99 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Thujone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thujone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thujone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thujone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Thujone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thujone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thujone

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Authors Title Published Journal PubMed Link
Remberg P et al. Characteristics, clinical effect profile and tolerability of a nasal spray preparation of Artemisia abrotanum L. for allergic rhinitis. 2004 Phytomedicine pmid:14971719
Umlauf D et al. Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). 2004 Phytochemistry pmid:15381410
Hall AC et al. Modulation of human GABAA and glycine receptor currents by menthol and related monoterpenoids. 2004 Eur. J. Pharmacol. pmid:15588619
Deiml T et al. Alpha-thujone reduces 5-HT3 receptor activity by an effect on the agonist-reduced desensitization. 2004 Neuropharmacology pmid:15002407
Santos-Gomes PC and Fernandes-Ferreira M Essential oils produced by in vitro shoots of sage (Salvia officinalis L.). 2003 J. Agric. Food Chem. pmid:12670167
Pitarokili D et al. Volatile metabolites from Salvia fruticosa as antifungal agents in soilborne pathogens. 2003 J. Agric. Food Chem. pmid:12744657
Holstege CP et al. Absinthe: return of the Green Fairy. 2002 Semin Neurol pmid:12170397
Gambelunghe C and Melai P Absinthe: enjoying a new popularity among young people? 2002 Forensic Sci. Int. pmid:12477641
Sirisoma NS et al. alpha- and beta-Thujones (herbal medicines and food additives): synthesis and analysis of hydroxy and dehydro metabolites. 2001 J. Agric. Food Chem. pmid:11308346
Höld KM et al. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. 2001 Chem. Res. Toxicol. pmid:11368559