MeSH term | MeSH ID | Detail |
---|---|---|
Insulin Resistance | D007333 | 99 associated lipids |
Seizures | D012640 | 87 associated lipids |
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thujone
MeSH term | MeSH ID | Detail |
---|---|---|
Insulin Resistance | D007333 | 99 associated lipids |
Seizures | D012640 | 87 associated lipids |
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Remberg P et al. | Characteristics, clinical effect profile and tolerability of a nasal spray preparation of Artemisia abrotanum L. for allergic rhinitis. | 2004 | Phytomedicine | pmid:14971719 |
Umlauf D et al. | Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). | 2004 | Phytochemistry | pmid:15381410 |
Hall AC et al. | Modulation of human GABAA and glycine receptor currents by menthol and related monoterpenoids. | 2004 | Eur. J. Pharmacol. | pmid:15588619 |
He X and Ortiz de Montellano PR | Alpha- and beta-thujone radical rearrangements and isomerizations. A new radical clock. | 2004 | J. Org. Chem. | pmid:15307740 |
Behrens M et al. | The human taste receptor hTAS2R14 responds to a variety of different bitter compounds. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15178431 |
He X and de Montellano PR | Radical rebound mechanism in cytochrome P-450-catalyzed hydroxylation of the multifaceted radical clocks alpha- and beta-thujone. | 2004 | J. Biol. Chem. | pmid:15258138 |
Chiang LC et al. | Antiviral activities of extracts and selected pure constituents of Ocimum basilicum. | 2005 | Clin. Exp. Pharmacol. Physiol. | pmid:16173941 |
Jiang Y et al. | Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes. | 2006 | Biochemistry | pmid:16401082 |
Lachenmeier DW et al. | Thujone--cause of absinthism? | 2006 | Forensic Sci. Int. | pmid:15896935 |
Lachenmeier DW et al. | Absinthe--a review. | 2006 | Crit Rev Food Sci Nutr | pmid:16891209 |