MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Seizures | D012640 | 87 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thujone
MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Seizures | D012640 | 87 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nikolić B et al. | Modulation of genotoxicity and DNA repair by plant monoterpenes camphor, eucalyptol and thujone in Escherichia coli and mammalian cells. | 2011 | Food Chem. Toxicol. | pmid:21620923 |
Hudson J et al. | The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildings. | 2011 | Int J Environ Res Public Health | pmid:22408584 |
Walch SG et al. | Antioxidant Capacity and Polyphenolic Composition as Quality Indicators for Aqueous Infusions of Salvia officinalis L. (sage tea). | 2011 | Front Pharmacol | pmid:22194722 |
Font X et al. | Detection, composition and treatment of volatile organic compounds from waste treatment plants. | 2011 | Sensors (Basel) | pmid:22163835 |
Tenore GC et al. | Antimicrobial and antioxidant properties of the essential oil of Salvia lanigera from Cyprus. | 2011 | Food Chem. Toxicol. | pmid:20977923 |
Lachenmeier DW and Walch SG | The choice of thujone as drug for diabetes. | 2011 | Nat. Prod. Res. | pmid:21988529 |
Alkhateeb H et al. | Skeletal muscle fatty acid oxidation is not directly associated with AMPK or ACC2 phosphorylation. | 2011 | Appl Physiol Nutr Metab | pmid:21574785 |
Toxicology and carcinogenesis studies of alpha,beta-thujone (CAS No. 76231-76-0) in F344/N rats and B6C3F1 mice (gavage studies). | 2011 | Natl Toxicol Program Tech Rep Ser | pmid:22127327 | |
Baddar NW et al. | Thujone corrects cholesterol and triglyceride profiles in diabetic rat model. | 2011 | Nat. Prod. Res. | pmid:21740283 |
Singh O et al. | Chamomile (Matricaria chamomilla L.): An overview. | 2011 | Pharmacogn Rev | pmid:22096322 |