Thujone

Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.

Cross Reference

Introduction

To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thujone?

Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thujone

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Seizures D012640 87 associated lipids
Insulin Resistance D007333 99 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Thujone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thujone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thujone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thujone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Thujone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thujone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thujone

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Authors Title Published Journal PubMed Link
Maia MF and Moore SJ Plant-based insect repellents: a review of their efficacy, development and testing. 2011 Malar. J. pmid:21411012
Arora R et al. Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. 2011 Evid Based Complement Alternat Med pmid:20976081
Lachenmeier DW and Walch SG The choice of thujone as drug for diabetes. 2011 Nat. Prod. Res. pmid:21988529
Abass K et al. Metabolism of α-thujone in human hepatic preparations in vitro. 2011 Xenobiotica pmid:21087116
Alkhateeb H et al. Skeletal muscle fatty acid oxidation is not directly associated with AMPK or ACC2 phosphorylation. 2011 Appl Physiol Nutr Metab pmid:21574785
Siveen KS and Kuttan G Augmentation of humoral and cell mediated immune responses by Thujone. 2011 Int. Immunopharmacol. pmid:21884824
Schmiderer C et al. Influence of gibberellin and daminozide on the expression of terpene synthases and on monoterpenes in common sage (Salvia officinalis). 2010 J. Plant Physiol. pmid:20163890
Sõukand R et al. Uninvited guests: traditional insect repellents in Estonia used against the clothes moth Tineola bisselliella, human flea Pulex irritons and bedbug Cimex lectularius. 2010 J. Insect Sci. pmid:21070174
Alkhateeb H and Bonen A Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscle. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20573988
Dolan LC et al. Naturally occurring food toxins. 2010 Toxins (Basel) pmid:22069686