| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
3
Thujone
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
Cross Reference
Introduction
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thujone?
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Int J Epidemiol (1)
- Proc. Natl. Acad. Sci. U.S.A. (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Others (2)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thujone
PubChem Associated disorders and diseases
What pathways are associated with Thujone
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thujone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Plant Physiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Others (4)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thujone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thujone?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Plant Physiol. (1)
- Proc. Natl. Acad. Sci. U.S.A. (1)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Thujone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thujone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thujone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Remberg P et al. | Characteristics, clinical effect profile and tolerability of a nasal spray preparation of Artemisia abrotanum L. for allergic rhinitis. | 2004 | Phytomedicine | pmid:14971719 |
| Umlauf D et al. | Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). | 2004 | Phytochemistry | pmid:15381410 |
| Hall AC et al. | Modulation of human GABAA and glycine receptor currents by menthol and related monoterpenoids. | 2004 | Eur. J. Pharmacol. | pmid:15588619 |
| Deiml T et al. | Alpha-thujone reduces 5-HT3 receptor activity by an effect on the agonist-reduced desensitization. | 2004 | Neuropharmacology | pmid:15002407 |
| Santos-Gomes PC and Fernandes-Ferreira M | Essential oils produced by in vitro shoots of sage (Salvia officinalis L.). | 2003 | J. Agric. Food Chem. | pmid:12670167 |
| Pitarokili D et al. | Volatile metabolites from Salvia fruticosa as antifungal agents in soilborne pathogens. | 2003 | J. Agric. Food Chem. | pmid:12744657 |
| Holstege CP et al. | Absinthe: return of the Green Fairy. | 2002 | Semin Neurol | pmid:12170397 |
| Gambelunghe C and Melai P | Absinthe: enjoying a new popularity among young people? | 2002 | Forensic Sci. Int. | pmid:12477641 |
| Waller PJ et al. | Plants as de-worming agents of livestock in the Nordic countries: historical perspective, popular beliefs and prospects for the future. | 2001 | Acta Vet. Scand. | pmid:11455900 |
| Sirisoma NS et al. | alpha- and beta-Thujones (herbal medicines and food additives): synthesis and analysis of hydroxy and dehydro metabolites. | 2001 | J. Agric. Food Chem. | pmid:11308346 |
| Höld KM et al. | Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. | 2001 | Chem. Res. Toxicol. | pmid:11368559 |
| Olsen RW | Absinthe and gamma-aminobutyric acid receptors. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10781032 |
| Höld KM et al. | Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10725394 |
| Strang J et al. | Absinthe: what's your poison? Though absinthe is intriguing, it is alcohol in general we should worry about. | 1999 Dec 18-25 | BMJ | pmid:10600949 |
| Meschler JP and Howlett AC | Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses. | 1999 | Pharmacol. Biochem. Behav. | pmid:10080239 |
| Haines JD | Absinthe--return of the green fairy. | 1998 | J Okla State Med Assoc | pmid:9793279 |
| Salisová M et al. | Comparison of conventional and ultrasonically assisted extractions of pharmaceutically active compounds from Salvia officinalis. | 1997 | Ultrason Sonochem | pmid:11237030 |
| Bonkovsky HL et al. | Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh). | 1992 | Biochem. Pharmacol. | pmid:1610401 |
| Monroe RR | Another diagnosis for Vincent Van Gogh? | 1991 | J. Nerv. Ment. Dis. | pmid:2007896 |
| Arnold WN | Absinthe. | 1989 | Sci. Am. | pmid:2658044 |