MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Seizures | D012640 | 87 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thujone
MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Seizures | D012640 | 87 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Walch SG et al. | Holistic Control of Herbal Teas and Tinctures Based on Sage (Salvia officinalis L.) for Compounds with Beneficial and Adverse Effects using NMR Spectroscopy. | 2012 | Anal Chem Insights | pmid:22493561 |
Alkhateeb H et al. | Skeletal muscle fatty acid oxidation is not directly associated with AMPK or ACC2 phosphorylation. | 2011 | Appl Physiol Nutr Metab | pmid:21574785 |
Dehal SS and Croteau R | Metabolism of monoterpenes: specificity of the dehydrogenases responsible for the biosynthesis of camphor, 3-thujone, and 3-isothujone. | 1987 | Arch. Biochem. Biophys. | pmid:3310901 |
Brieskorn CH and Schwack W | [Condensation of thujone with biogenic amines and amino acids]. | 1983 | Arch. Pharm. (Weinheim) | pmid:6882159 |
Behrens M et al. | The human taste receptor hTAS2R14 responds to a variety of different bitter compounds. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15178431 |
Bonkovsky HL et al. | Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh). | 1992 | Biochem. Pharmacol. | pmid:1610401 |
Jiang Y et al. | Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes. | 2006 | Biochemistry | pmid:16401082 |
Strang J et al. | Absinthe: what's your poison? Though absinthe is intriguing, it is alcohol in general we should worry about. | 1999 Dec 18-25 | BMJ | pmid:10600949 |
Rivera EM et al. | Central α- and β-thujone: similar anxiogenic-like effects and differential modulation on GABAA receptors in neonatal chicks. | 2014 | Brain Res. | pmid:24486357 |
Chapuis Y | [Absinthe rehabilitated]. | 2013 | Bull. Acad. Natl. Med. | pmid:24919378 |