| MeSH term | MeSH ID | Detail |
|---|---|---|
| Seizures | D012640 | 87 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Total
3
Thujone
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
Cross Reference
Introduction
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thujone?
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thujone
PubChem Associated disorders and diseases
What pathways are associated with Thujone
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thujone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Plant Physiol. (2)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Others (4)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thujone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thujone?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Plant Physiol. (1)
- Proc. Natl. Acad. Sci. U.S.A. (1)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Thujone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thujone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thujone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gesell A et al. | The gymnosperm cytochrome P450 CYP750B1 catalyzes stereospecific monoterpene hydroxylation of (+)-sabinene in thujone biosynthesis in western redcedar. | 2015 | Plant Physiol. | pmid:25829465 |
| Karban R et al. | Deciphering the language of plant communication: volatile chemotypes of sagebrush. | 2014 | New Phytol. | pmid:24920243 |
| Rivera EM et al. | Central α- and β-thujone: similar anxiogenic-like effects and differential modulation on GABAA receptors in neonatal chicks. | 2014 | Brain Res. | pmid:24486357 |
| D'Ulivo L | The absinthe challenge. | 2014 | Anal Bioanal Chem | pmid:24632744 |
| Horváth G et al. | TLC-direct bioautography for determination of antibacterial activity of Artemisia adamsii essential oil. | 2013 Nov-Dec | J AOAC Int | pmid:24645495 |
| Ehrnhöfer-Ressler MM et al. | Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts. | 2013 | J. Agric. Food Chem. | pmid:23488631 |
| Bouajaj S et al. | Antibacterial, allelopathic and antioxidant activities of essential oil of Salvia officinalis L. growing wild in the Atlas Mountains of Morocco. | 2013 | Nat. Prod. Res. | pmid:23240623 |
| Rajput SB and Karuppayil SM | Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. | 2013 | Springerplus | pmid:23449869 |
| El Montassir D et al. | Attempts to separate (-)-α-thujone, (+)-β-thujone epimers from camphor enantiomers by enantioselective HPLC with polarimetric detection. | 2013 | J Sep Sci | pmid:23378105 |
| Arceusz A et al. | Comparison of different extraction methods for the determination of α- and β-thujone in sage (Salvia officinalis L.) herbal tea. | 2013 | J Sep Sci | pmid:23843295 |
| Waidyanatha S et al. | Toxicokinetics of α-thujone following intravenous and gavage administration of α-thujone or α- and β-thujone mixture in male and female F344/N rats and B6C3F1 mice. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23669748 |
| Pelkonen O et al. | Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment. | 2013 | Regul. Toxicol. Pharmacol. | pmid:23201408 |
| Foster AJ et al. | Identification of genes in Thuja plicata foliar terpenoid defenses. | 2013 | Plant Physiol. | pmid:23388118 |
| Czyzewska MM and Mozrzymas JW | Monoterpene α-thujone exerts a differential inhibitory action on GABA(A) receptors implicated in phasic and tonic GABAergic inhibition. | 2013 | Eur. J. Pharmacol. | pmid:23376563 |
| Kleine S and Müller C | Differences in shoot and root terpenoid profiles and plant responses to fertilisation in Tanacetum vulgare. | 2013 | Phytochemistry | pmid:24128753 |
| Chapuis Y | [Absinthe rehabilitated]. | 2013 | Bull. Acad. Natl. Med. | pmid:24919378 |
| Grausgruber-Gröger S et al. | Seasonal influence on gene expression of monoterpene synthases in Salvia officinalis (Lamiaceae). | 2012 | J. Plant Physiol. | pmid:22196947 |
| Walch SG et al. | Holistic Control of Herbal Teas and Tinctures Based on Sage (Salvia officinalis L.) for Compounds with Beneficial and Adverse Effects using NMR Spectroscopy. | 2012 | Anal Chem Insights | pmid:22493561 |
| Szczot M et al. | Modulation of GABAergic synaptic currents and current responses by α-thujone and dihydroumbellulone. | 2012 | J. Nat. Prod. | pmid:22364543 |
| Maia MF and Moore SJ | Plant-based insect repellents: a review of their efficacy, development and testing. | 2011 | Malar. J. | pmid:21411012 |
| Arora R et al. | Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. | 2011 | Evid Based Complement Alternat Med | pmid:20976081 |
| Nikolić B et al. | Modulation of genotoxicity and DNA repair by plant monoterpenes camphor, eucalyptol and thujone in Escherichia coli and mammalian cells. | 2011 | Food Chem. Toxicol. | pmid:21620923 |
| Biswas R et al. | Thujone-Rich Fraction of Thuja occidentalis Demonstrates Major Anti-Cancer Potentials: Evidences from In Vitro Studies on A375 Cells. | 2011 | Evid Based Complement Alternat Med | pmid:21647317 |
| Hudson J et al. | The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildings. | 2011 | Int J Environ Res Public Health | pmid:22408584 |
| Walch SG et al. | Determination of the biologically active flavour substances thujone and camphor in foods and medicines containing sage (Salvia officinalis L.). | 2011 | Chem Cent J | pmid:21777420 |
| Walch SG et al. | Antioxidant Capacity and Polyphenolic Composition as Quality Indicators for Aqueous Infusions of Salvia officinalis L. (sage tea). | 2011 | Front Pharmacol | pmid:22194722 |
| Font X et al. | Detection, composition and treatment of volatile organic compounds from waste treatment plants. | 2011 | Sensors (Basel) | pmid:22163835 |
| Tenore GC et al. | Antimicrobial and antioxidant properties of the essential oil of Salvia lanigera from Cyprus. | 2011 | Food Chem. Toxicol. | pmid:20977923 |
| Lachenmeier DW and Walch SG | The choice of thujone as drug for diabetes. | 2011 | Nat. Prod. Res. | pmid:21988529 |
| Abass K et al. | Metabolism of α-thujone in human hepatic preparations in vitro. | 2011 | Xenobiotica | pmid:21087116 |
| Alkhateeb H et al. | Skeletal muscle fatty acid oxidation is not directly associated with AMPK or ACC2 phosphorylation. | 2011 | Appl Physiol Nutr Metab | pmid:21574785 |
| Toxicology and carcinogenesis studies of alpha,beta-thujone (CAS No. 76231-76-0) in F344/N rats and B6C3F1 mice (gavage studies). | 2011 | Natl Toxicol Program Tech Rep Ser | pmid:22127327 | |
| Baddar NW et al. | Thujone corrects cholesterol and triglyceride profiles in diabetic rat model. | 2011 | Nat. Prod. Res. | pmid:21740283 |
| Siveen KS and Kuttan G | Thujone inhibits lung metastasis induced by B16F-10 melanoma cells in C57BL/6 mice. | 2011 | Can. J. Physiol. Pharmacol. | pmid:21905822 |
| Siveen KS and Kuttan G | Augmentation of humoral and cell mediated immune responses by Thujone. | 2011 | Int. Immunopharmacol. | pmid:21884824 |
| Singh O et al. | Chamomile (Matricaria chamomilla L.): An overview. | 2011 | Pharmacogn Rev | pmid:22096322 |
| Eckert GP | Traditional used Plants against Cognitive Decline and Alzheimer Disease. | 2010 | Front Pharmacol | pmid:21833177 |
| Polatoglu K et al. | Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype. | 2010 | J Oleo Sci | pmid:20484836 |
| Schmiderer C et al. | Influence of gibberellin and daminozide on the expression of terpene synthases and on monoterpenes in common sage (Salvia officinalis). | 2010 | J. Plant Physiol. | pmid:20163890 |
| Sõukand R et al. | Uninvited guests: traditional insect repellents in Estonia used against the clothes moth Tineola bisselliella, human flea Pulex irritons and bedbug Cimex lectularius. | 2010 | J. Insect Sci. | pmid:21070174 |
| Lachenmeier DW and Uebelacker M | Risk assessment of thujone in foods and medicines containing sage and wormwood--evidence for a need of regulatory changes? | 2010 | Regul. Toxicol. Pharmacol. | pmid:20727933 |
| Mighri H et al. | Composition and intraspecific chemical variability of the essential oil from Artemisia herba-alba growing wild in a Tunisian arid zone. | 2010 | Chem. Biodivers. | pmid:21072770 |
| Alkhateeb H and Bonen A | Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscle. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20573988 |
| Dolan LC et al. | Naturally occurring food toxins. | 2010 | Toxins (Basel) | pmid:22069686 |
| Laciar A et al. | Antibacterial and antioxidant activities of the essential oil of Artemisia echegarayi Hieron. (Asteraceae). | 2009 Oct-Dec | Rev. Argent. Microbiol. | pmid:20085186 |
| Jiang Y and Ortiz de Montellano PR | Cooperative effects on radical recombination in CYP3A4-catalyzed oxidation of the radical clock beta-thujone. | 2009 | Chembiochem | pmid:19189363 |
| Shah AS et al. | Motile cilia of human airway epithelia are chemosensory. | 2009 | Science | pmid:19628819 |
| Oyedeji AO et al. | Compositional variation of the essential oils of Artemisia afra Jacq. from three provinces in South Africa--a case study of its safety. | 2009 | Nat Prod Commun | pmid:19634335 |
| Eadie MJ | Absinthe, epileptic seizures and Valentin Magnan. | 2009 | J R Coll Physicians Edinb | pmid:19831287 |
| Tzakou O and Loukis A | Chemical composition of the essential oil of Achillea umbellata growing in Greece. | 2009 | Nat. Prod. Res. | pmid:19235027 |