Thujone

Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.

Cross Reference

Introduction

To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thujone?

Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thujone

MeSH term MeSH ID Detail
Seizures D012640 87 associated lipids
Insulin Resistance D007333 99 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Thujone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thujone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thujone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thujone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Thujone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thujone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thujone

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Authors Title Published Journal PubMed Link
Eckert GP Traditional used Plants against Cognitive Decline and Alzheimer Disease. 2010 Front Pharmacol pmid:21833177
Polatoglu K et al. Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype. 2010 J Oleo Sci pmid:20484836
Sõukand R et al. Uninvited guests: traditional insect repellents in Estonia used against the clothes moth Tineola bisselliella, human flea Pulex irritons and bedbug Cimex lectularius. 2010 J. Insect Sci. pmid:21070174
Lachenmeier DW and Uebelacker M Risk assessment of thujone in foods and medicines containing sage and wormwood--evidence for a need of regulatory changes? 2010 Regul. Toxicol. Pharmacol. pmid:20727933
Mighri H et al. Composition and intraspecific chemical variability of the essential oil from Artemisia herba-alba growing wild in a Tunisian arid zone. 2010 Chem. Biodivers. pmid:21072770
Dolan LC et al. Naturally occurring food toxins. 2010 Toxins (Basel) pmid:22069686
Nikolić B et al. Modulation of genotoxicity and DNA repair by plant monoterpenes camphor, eucalyptol and thujone in Escherichia coli and mammalian cells. 2011 Food Chem. Toxicol. pmid:21620923
Hudson J et al. The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildings. 2011 Int J Environ Res Public Health pmid:22408584
Walch SG et al. Antioxidant Capacity and Polyphenolic Composition as Quality Indicators for Aqueous Infusions of Salvia officinalis L. (sage tea). 2011 Front Pharmacol pmid:22194722
Tenore GC et al. Antimicrobial and antioxidant properties of the essential oil of Salvia lanigera from Cyprus. 2011 Food Chem. Toxicol. pmid:20977923