Ivanov SS et al. |
Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. |
2010 |
J. Biol. Chem. |
pmid:20813839
|
Newman CM et al. |
Post-translational processing of Schizosaccharomyces pombe YPT proteins. |
1992 |
J. Biol. Chem. |
pmid:1597466
|
Bradfute DL et al. |
Squalene synthase-deficient mutant of Chinese hamster ovary cells. |
1992 |
J. Biol. Chem. |
pmid:1526971
|
Gibbs JB et al. |
Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. |
1993 |
J. Biol. Chem. |
pmid:8463291
|
Biermann BJ et al. |
Novel isoprenylated proteins identified by an expression library screen. |
1994 |
J. Biol. Chem. |
pmid:7929216
|
Lerro KA and Prestwich GD |
Cloning and sequencing of a cDNA for the hemolymph juvenile hormone binding protein of larval Manduca sexta. |
1990 |
J. Biol. Chem. |
pmid:2246263
|
Kisselev O et al. |
Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit. |
1995 |
J. Biol. Chem. |
pmid:7592699
|
Fujiyama A et al. |
S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation. |
1991 |
J. Biol. Chem. |
pmid:1917931
|
Maltese WA and Erdman RA |
Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins. |
1989 |
J. Biol. Chem. |
pmid:2808372
|
Keller RK et al. |
Studies on the regulation of glycoprotein biosynthesis. An investigation of the rate-limiting steps of dolichyl phosphate biosynthesis. |
1979 |
J. Biol. Chem. |
pmid:489612
|
Gonzalez-Pacanowska D et al. |
Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. |
1988 |
J. Biol. Chem. |
pmid:3335546
|
Bostedor RG et al. |
Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol. |
1997 |
J. Biol. Chem. |
pmid:9083051
|
Koeppe JK et al. |
A specific photoaffinity label for hemolymph and ovarian juvenile hormone-binding proteins in Leucophaea maderae. |
1984 |
J. Biol. Chem. |
pmid:6699014
|
Popják G et al. |
Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. |
1969 |
J. Biol. Chem. |
pmid:4388617
|
Roullet JB et al. |
Farnesol inhibits L-type Ca2+ channels in vascular smooth muscle cells. |
1997 |
J. Biol. Chem. |
pmid:9405427
|
Edmond J et al. |
Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene. |
1971 |
J. Biol. Chem. |
pmid:4399596
|
Cornforth JW et al. |
Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. |
1966 |
J. Biol. Chem. |
pmid:4288360
|
Allen CM et al. |
A long chain terpenyl pyrophosphate synthetase from Micrococcus lysodeikticus. |
1967 |
J. Biol. Chem. |
pmid:4290445
|
Dorsey JK and Porter JW |
The inhibition of mevalonic kinase by geranyl and farnesyl pyrophosphates. |
1968 |
J. Biol. Chem. |
pmid:4300840
|
Carel K et al. |
Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes. |
1996 |
J. Biol. Chem. |
pmid:8940037
|
Sobotka-Briner C and Chelsky D |
COOH-terminal methylation of lamin B and inhibition of methylation by farnesylated peptides corresponding to lamin B and other CAAX motif proteins. |
1992 |
J. Biol. Chem. |
pmid:1601879
|
McGuire TF et al. |
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. |
1996 |
J. Biol. Chem. |
pmid:8910319
|
Onono F et al. |
Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. |
2013 |
J. Biol. Chem. |
pmid:23908355
|
Miquel K et al. |
Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells. |
1998 |
J. Biol. Chem. |
pmid:9748300
|
Anthony ML et al. |
Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells. |
1999 |
J. Biol. Chem. |
pmid:10391908
|
Roullet JB et al. |
Modulation of neuronal voltage-gated calcium channels by farnesol. |
1999 |
J. Biol. Chem. |
pmid:10464274
|
Slakey LL et al. |
The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. |
1972 |
J. Biol. Chem. |
pmid:4337504
|
Polito A et al. |
Artificial substrates in squalene and sterol biosynthesis. |
1972 |
J. Biol. Chem. |
pmid:4337856
|
Rosado JA and Sage SO |
Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets. |
2001 |
J. Biol. Chem. |
pmid:11278479
|
Wright MM et al. |
Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. |
2001 |
J. Biol. Chem. |
pmid:11306571
|
Daily D et al. |
Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. |
2001 |
J. Biol. Chem. |
pmid:11290748
|
Epstein WW and Rilling HC |
Studies on the mechanism of squalene biosynthesis. The structure of presqualene pyrophosphate. |
1970 |
J. Biol. Chem. |
pmid:4318477
|
Rilling HC |
A new intermediate in the biosynthesis of squalene. |
1966 |
J. Biol. Chem. |
pmid:4287912
|
Chakrabarti D et al. |
Protein farnesyltransferase and protein prenylation in Plasmodium falciparum. |
2002 |
J. Biol. Chem. |
pmid:12194969
|
Golczak M et al. |
Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. |
2008 |
J. Biol. Chem. |
pmid:18195010
|
Joo JH and Jetten AM |
NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. |
2008 |
J. Biol. Chem. |
pmid:18424438
|
Hanley K et al. |
Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. |
2000 |
J. Biol. Chem. |
pmid:10753967
|
Tschantz WR et al. |
Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase. |
2001 |
J. Biol. Chem. |
pmid:11078725
|
Hubálek F et al. |
Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. |
2005 |
J. Biol. Chem. |
pmid:15710600
|
Kisselev OG et al. |
A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling. |
1994 |
J. Biol. Chem. |
pmid:8063769
|
Lübben M and Morand K |
Novel prenylated hemes as cofactors of cytochrome oxidases. Archaea have modified hemes A and O. |
1994 |
J. Biol. Chem. |
pmid:8063781
|
Correll CC et al. |
Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
1994 |
J. Biol. Chem. |
pmid:8021239
|
Cox AD et al. |
The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. |
1994 |
J. Biol. Chem. |
pmid:8034681
|
Sever N et al. |
Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol. |
2003 |
J. Biol. Chem. |
pmid:14563840
|
Fogelman AM et al. |
Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia. |
1975 |
J. Biol. Chem. |
pmid:1116997
|
de Ropp JS and Troy FA |
2H NMR investigation of the organization and dynamics of polyisoprenols in membranes. |
1985 |
J. Biol. Chem. |
pmid:4066690
|
Touhara K and Prestwich GD |
Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. |
1993 |
J. Biol. Chem. |
pmid:8396141
|
Marom M et al. |
Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid. |
1995 |
J. Biol. Chem. |
pmid:7673206
|
Hartman HL et al. |
Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium. |
2004 |
J. Biol. Chem. |
pmid:15131129
|
Chen CK et al. |
Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene omega-hydroxylase CYP4C7. |
2010 |
J. Biol. Inorg. Chem. |
pmid:19727859
|
Chen CK et al. |
The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. |
2008 |
J. Biol. Inorg. Chem. |
pmid:18392864
|
Granshaw T et al. |
Circadian rhythms in Neurospora crassa: farnesol or geraniol allow expression of rhythmicity in the otherwise arrhythmic strains frq10, wc-1, and wc-2. |
2003 |
J. Biol. Rhythms |
pmid:12932081
|
Muramatsu M et al. |
Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols. |
2008 |
J. Biosci. Bioeng. |
pmid:18930003
|
Muramatsu M et al. |
Alkaline pH enhances farnesol production by Saccharomyces cerevisiae. |
2009 |
J. Biosci. Bioeng. |
pmid:19577192
|
Cho SW et al. |
Positive regulation of osteogenesis by bile acid through FXR. |
2013 |
J. Bone Miner. Res. |
pmid:23609136
|
Shohami E et al. |
The Ras inhibitor S-trans, trans-farnesylthiosalicylic acid exerts long-lasting neuroprotection in a mouse closed head injury model. |
2003 |
J. Cereb. Blood Flow Metab. |
pmid:12796721
|
Yang Z et al. |
Host plant volatiles synergize response to sex pheromone in codling moth, Cydia pomonella. |
2004 |
J. Chem. Ecol. |
pmid:15139312
|
Shimomura K et al. |
2,3-Dihydrohomofarnesal: female sex attractant pheromone component of Callosobruchus rhodesianus (Pic). |
2010 |
J. Chem. Ecol. |
pmid:20607368
|
Shimomura K et al. |
Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. |
2008 |
J. Chem. Ecol. |
pmid:18351422
|
Xiao Y et al. |
A two-component female-produced pheromone of the spider Pholcus beijingensis. |
2009 |
J. Chem. Ecol. |
pmid:19579045
|
Hanson JR and Nyfeler R |
Studies in terpenoid biosynthesis. Part 18. Biosynthesis of culmorin. |
1976 |
J. Chem. Soc. Perkin Trans. I |
pmid:1034641
|
Canonica L et al. |
Biosynthesis of mycophenolic acid. |
1972 |
J. Chem. Soc. Perkin Trans. I |
pmid:4674609
|
Zhao M et al. |
Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. |
2008 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:18534927
|
O'Donnell MP et al. |
Lovastatin inhibits proliferation of rat mesangial cells. |
1993 |
J. Clin. Invest. |
pmid:8423236
|
Roullet JB et al. |
Farnesyl analogues inhibit vasoconstriction in animal and human arteries. |
1996 |
J. Clin. Invest. |
pmid:8636420
|
Neuhüser T et al. |
Responsiveness of the adult cricket (Gryllus bimaculatus and Acheta domesticus) retrocerebral complex to allatostatin-1 from a cockroach, Diploptera punctata. |
1994 |
J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. |
pmid:8014257
|
Koo H et al. |
Apigenin and tt-farnesol with fluoride effects on S. mutans biofilms and dental caries. |
2005 |
J. Dent. Res. |
pmid:16246933
|
Katsuyama M et al. |
A novel method to control the balance of skin microflora. Part 1. Attack on biofilm of Staphylococcus aureus without antibiotics. |
2005 |
J. Dermatol. Sci. |
pmid:15927813
|
Katsuyama M et al. |
A novel method to control the balance of skin microflora Part 2. A study to assess the effect of a cream containing farnesol and xylitol on atopic dry skin. |
2005 |
J. Dermatol. Sci. |
pmid:15927814
|
Green SA et al. |
Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). |
2012 |
J. Exp. Bot. |
pmid:22162874
|
Lin HP et al. |
Localization of isoprenylated antigen of hepatitis delta virus by anti-farnesyl antibodies. |
1999 |
J. Gen. Virol. |
pmid:9934689
|
Reif S et al. |
The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. |
1999 |
J. Hepatol. |
pmid:10604579
|
Reif S et al. |
Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid. |
2004 |
J. Hepatol. |
pmid:15288472
|
Roullet JB et al. |
Inhibition of Ca2+ uptake into A7r5 vascular smooth muscle cells by farnesol: lack of effect on membrane fluidity and Ca2+-ATPase activities. |
1997 |
J. Hypertens. |
pmid:9488229
|
Madhavan K et al. |
Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase. |
1973 |
J. Insect Physiol. |
pmid:4631837
|
Spielman A and Skaff V |
Inhibition of metamorphosis and of ecdysis in mosquitoes. |
1967 |
J. Insect Physiol. |
pmid:6043875
|
Krishnakumaran A and Schneiderman HA |
Prothoracotrophic activity of compounds that mimic juvenile hormone. |
1965 |
J. Insect Physiol. |
pmid:5848789
|
Schneiderman HA et al. |
Juvenile hormone activity of structurally unrelated compounds. |
1965 |
J. Insect Physiol. |
pmid:5848792
|
Lanzrein B |
Influence of a juvenile hormone analogue on vitellogenin synthesis and oögenesis in larvae of Nauphoeta cinerea. |
1974 |
J. Insect Physiol. |
pmid:4413859
|
Matsuzawa T et al. |
EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium. |
2014 |
J. Invest. Dermatol. |
pmid:24384694
|
Mor A et al. |
Inhibition of contact sensitivity by farnesylthiosalicylic acid-amide, a potential Rap1 inhibitor. |
2011 |
J. Invest. Dermatol. |
pmid:21716322
|
Hanley K et al. |
Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. |
1999 |
J. Invest. Dermatol. |
pmid:10571735
|
Halaschek-Wiener J et al. |
Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo. |
2003 |
J. Invest. Dermatol. |
pmid:12535206
|
Baker FC et al. |
Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta. |
1983 |
J. Lipid Res. |
pmid:6366103
|
Sofer SS and Rilling HC |
Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate. |
1969 |
J. Lipid Res. |
pmid:4305712
|
Slakey LL et al. |
Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. |
1973 |
J. Lipid Res. |
pmid:4351784
|
Aboushadi N and Krisans SK |
Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines. |
1998 |
J. Lipid Res. |
pmid:9741690
|
Hanley K et al. |
Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D. |
2001 |
J. Lipid Res. |
pmid:11254751
|
Hiyoshi H et al. |
Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. |
2003 |
J. Lipid Res. |
pmid:12518031
|
Prashad M et al. |
N-(arylalkyl)farnesylamines: new potent squalene synthetase inhibitors. |
1993 |
J. Med. Chem. |
pmid:8496919
|
Ling Y et al. |
Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of antihepatocellular carcinoma activity. |
2011 |
J. Med. Chem. |
pmid:21504204
|
Goldberg L et al. |
New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models. |
2009 |
J. Med. Chem. |
pmid:19072665
|
Grienke U et al. |
Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai. |
2010 |
J. Med. Chem. |
pmid:20014777
|
de Montellano PR et al. |
Inhibition of squalene synthetase by farnesyl pyrophosphate analogues. |
1977 |
J. Med. Chem. |
pmid:189031
|
Gibbs BS et al. |
Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation. |
1999 |
J. Med. Chem. |
pmid:10508429
|
Marciano D et al. |
Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth. |
1995 |
J. Med. Chem. |
pmid:7731012
|
Sharma RN and Saxena KN |
Orientation and developmental inhibition in the housefly by certain terpenoids. |
1974 |
J. Med. Entomol. |
pmid:4281838
|
Brilhante RS et al. |
Histoplasma capsulatum in planktonic and biofilm forms: in vitro susceptibility to amphotericin B, itraconazole and farnesol. |
2015 |
J. Med. Microbiol. |
pmid:25657300
|
McAlester G et al. |
Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. |
2008 |
J. Med. Microbiol. |
pmid:18436588
|
Ward SM et al. |
TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras. |
2002 |
J. Mol. Cell. Cardiol. |
pmid:12392895
|