2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Huelin FE and Murray KE | Alpha-farnesene in the natural coating of apples. | 1966 | Nature | pmid:5967802 |
Monro J and Bailey PT | Influence of radiation on ovarian maturation and histolysis of pupal fat body in Diptera. | 1965 | Nature | pmid:5885870 |
Calam DH | Species and sex-specific compounds from the heads of male bumblebees (Bombus spp.). | 1969 | Nature | pmid:5765060 |
Goldstein JL and Brown MS | Regulation of the mevalonate pathway. | 1990 | Nature | pmid:1967820 |
Farag MA and Al-Mahdy DA | Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils. | 2013 | Nat. Prod. Res. | pmid:22690913 |
Cortés M et al. | Drimenol: A versatile synthon for compounds with trans-drimane skeleton. | 2011 | Nat Prod Commun | pmid:21560760 |
Lichtor PA and Miller SJ | Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation. | 2012 | Nat Chem | pmid:23174978 |
Cotoras M et al. | Farnesol induces apoptosis-like phenotype in the phytopathogenic fungus Botrytis cinerea. | 2013 Jan-Feb | Mycologia | pmid:22962358 |
Liu P et al. | Farnesol induces apoptosis and oxidative stress in the fungal pathogen Penicillium expansum. | 2010 Mar-Apr | Mycologia | pmid:20361499 |
Gonçalves O et al. | Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. | 2011 | Mutat. Res. | pmid:21453784 |