2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Song L | Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography. | 2009 Jul-Aug | Biotechnol. Prog. | pmid:19569196 |
Cushion MT et al. | Biofilm formation by Pneumocystis spp. | 2009 | Eukaryotic Cell | pmid:18820078 |
Rennemeier C et al. | Microbial quorum-sensing molecules induce acrosome loss and cell death in human spermatozoa. | 2009 | Infect. Immun. | pmid:19687207 |
Chen F et al. | Tooth-binding micelles for dental caries prevention. | 2009 | Antimicrob. Agents Chemother. | pmid:19704121 |
Goldberg L et al. | New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models. | 2009 | J. Med. Chem. | pmid:19072665 |
Ohto C et al. | Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19129660 |
Décanis N et al. | Farnesol promotes epithelial cell defense against Candida albicans through Toll-like receptor 2 expression, interleukin-6 and human beta-defensin 2 production. | 2009 | Cytokine | pmid:19121950 |
Rhome R and Del Poeta M | Lipid signaling in pathogenic fungi. | 2009 | Annu. Rev. Microbiol. | pmid:19450140 |
Jeon JG et al. | Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms. | 2009 | BMC Microbiol. | pmid:19863808 |
Xiao Y et al. | A two-component female-produced pheromone of the spider Pholcus beijingensis. | 2009 | J. Chem. Ecol. | pmid:19579045 |