2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cornforth JW et al. | Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. | 1966 | J. Biol. Chem. | pmid:4288360 |
Rilling HC | A new intermediate in the biosynthesis of squalene. | 1966 | J. Biol. Chem. | pmid:4287912 |
Huelin FE and Murray KE | Alpha-farnesene in the natural coating of apples. | 1966 | Nature | pmid:5967802 |
Smejkal V et al. | [Antiulcerous effect of various esters of farnesylacetic acid on the gastric mucosa in guinea pigs and rats]. | 1966 | Cesk Gastroenterol Vyz | pmid:5934910 |
Lima JP et al. | [Gefarnate (DA-688) in the treatment of peptic ulcer; immediate results]. | 1966 | Rev Bras Med | pmid:5940586 |
Patrassi G | [The relationship between collagenosis and rheumatic disease]. | 1966 | Concours Med | pmid:5904237 |
Donninger C and Popják G | Studies on the biosynthesis of cholesterol. 18. The stereospecificity of mevaldate reductase and the biosynthesis of asymmetrically labelled farnesyl pyrophosphate. | 1966 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:4379290 |
Nery AL and Nascif R | [Analysis of the value of the product geranyl farnesyl acetate (Gefarnate) in the treatment of peptic ulcer]. | 1966 | Hospital (Rio J) | pmid:5295886 |
Law JH et al. | Synthesis of a material with high juvenile hormone activity. | 1966 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5221241 |
Benedict CR et al. | Properties of farnesyl pyrophosphate synthetase of pig liver. | 1965 | Arch. Biochem. Biophys. | pmid:4284635 |