2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhao Y et al. | 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells. | 2016 | Eur. J. Cancer | pmid:27710830 |
pmid:27665610 | ||||
pmid:27623739 | ||||
Seman-Kamarulzaman AF et al. | Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic Pathway in Plant. | 2016 | PLoS ONE | pmid:27560927 |
pmid:27440491 | ||||
Sun J et al. | A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel. | 2016 | Acta Biomater | pmid:27422196 |
Bandara HM et al. | Incorporation of Farnesol Significantly Increases the Efficacy of Liposomal Ciprofloxacin against Pseudomonas aeruginosa Biofilms in Vitro. | 2016 | Mol. Pharm. | pmid:27383205 |
pmid:27357648 | ||||
Mohamed MA et al. | Polyacrylamide gel miniaturization improves protein visualization and autoradiographic detection. | 1989 | Anal. Biochem. | pmid:2729547 |
pmid:27239017 | ||||
Inoue Y et al. | Farnesol-Induced Disruption of the Staphylococcus aureus Cytoplasmic Membrane. | 2016 | Biol. Pharm. Bull. | pmid:27150138 |
pmid:27138105 | ||||
Léger T et al. | The Metacaspase (Mca1p) Restricts O-glycosylation During Farnesol-induced Apoptosis in Candida albicans. | 2016 | Mol. Cell Proteomics | pmid:27125826 |
pmid:27021020 | ||||
pmid:26992462 | ||||
pmid:26972663 | ||||
pmid:26968084 | ||||
Zhu J et al. | Mevalonate-Farnesal Biosynthesis in Ticks: Comparative Synganglion Transcriptomics and a New Perspective. | 2016 | PLoS ONE | pmid:26959814 |
pmid:26923572 | ||||
pmid:26905659 | ||||
Lemaire B et al. | Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. | 2016 | Toxicol. Appl. Pharmacol. | pmid:26853319 |
Cheng HL et al. | Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways. | 2016 | Oncotarget | pmid:26848867 |
Jung SI et al. | Comparison of E,E-Farnesol Secretion and the Clinical Characteristics of Candida albicans Bloodstream Isolates from Different Multilocus Sequence Typing Clades. | 2016 | PLoS ONE | pmid:26848577 |
Abdel-Rhman SH et al. | Effect of Tyrosol and Farnesol on Virulence and Antibiotic Resistance of Clinical Isolates of Pseudomonas aeruginosa. | 2015 | Biomed Res Int | pmid:26844228 |
Casey PJ et al. | p21ras is modified by a farnesyl isoprenoid. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2682646 |
Lowy DR and Willumsen BM | Protein modification: new clue to Ras lipid glue. | 1989 | Nature | pmid:2677741 |
Agnew WS and Popják G | Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes. | 1978 | J. Biol. Chem. | pmid:26684 |
pmid:26669506 | ||||
Torabi S and Mo H | Trans, trans-farnesol as a mevalonate-derived inducer of murine 3T3-F442A pre-adipocyte differentiation. | 2016 | Exp. Biol. Med. (Maywood) | pmid:26660152 |
pmid:26626450 | ||||
pmid:26546815 | ||||
Kostoulias X et al. | Impact of a Cross-Kingdom Signaling Molecule of Candida albicans on Acinetobacter baumannii Physiology. | 2015 | Antimicrob. Agents Chemother. | pmid:26482299 |
pmid:26442918 | ||||
Hameiri-Grossman M et al. | The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growth. | 2015 | Oncotarget | pmid:26393682 |
pmid:26365385 | ||||
pmid:26341906 | ||||
Strube-Bloss MF et al. | Extracting the Behaviorally Relevant Stimulus: Unique Neural Representation of Farnesol, a Component of the Recruitment Pheromone of Bombus terrestris. | 2015 | PLoS ONE | pmid:26340263 |
pmid:26318416 | ||||
Lopez-Medina E et al. | Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis. | 2015 | PLoS Pathog. | pmid:26313907 |
Joo JH et al. | Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells. | 2015 | Biochem. Pharmacol. | pmid:26275811 |
Krause J et al. | Prostaglandin E2 from Candida albicans Stimulates the Growth of Staphylococcus aureus in Mixed Biofilms. | 2015 | PLoS ONE | pmid:26262843 |
Mogen AB et al. | Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms. | 2015 | PLoS ONE | pmid:26222384 |
pmid:26198568 | ||||
Hargarten JC et al. | Candida albicans Quorum Sensing Molecules Stimulate Mouse Macrophage Migration. | 2015 | Infect. Immun. | pmid:26195556 |
pmid:26162644 | ||||
Ershova LS et al. | [The action of a juvenile hormone synthetic analog--ether-farnesol on Xenopsylla cheopis fleas]. | 1989 Sep-Oct | Parazitologia | pmid:2616197 |
pmid:26143865 | ||||
Supuran CT | Nanoparticles for controlled release of anti-biofilm agents WO2014130994 (A1): a patent evaluation. | 2015 | Expert Opin Ther Pat | pmid:26028186 |
pmid:25976810 | ||||
Stoddart CA et al. | Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque. | 2015 | Antimicrob. Agents Chemother. | pmid:25941222 |