2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Tóth M et al. | Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. | 2003 | Pest Manag. Sci. | pmid:12701702 |
Smalley KS and Eisen TG | Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells. | 2003 | Int. J. Cancer | pmid:12673674 |
Jones TH et al. | Farnesylamine from the ant Monomorium fieldi Forel. | 2003 | J. Nat. Prod. | pmid:12662086 |
Clarke HC et al. | Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. | 2003 | J. Am. Soc. Nephrol. | pmid:12660318 |
Katzav A et al. | Inhibition of ras by farnesylthiosalicylate significantly reduces the levels of autoantibodies in two animal models of the antiphospholipid syndrome. | 2003 | Immunobiology | pmid:12638903 |
Zoccarato F et al. | The adenosine inhibition of glutamate exocytosis in synaptosomes is removed by the collapse of the vesicle-cytosol deltapH plus the opening of farnesol-sensitive Ca(2+) channels. | 2003 | Cell Calcium | pmid:12618148 |
Ortiz de Montellano PR et al. | Letter: Squalene synthetase. Differentiation between the two substrate binding sites by a substrate analogue. | 1976 | J. Am. Chem. Soc. | pmid:1254859 |
Halaschek-Wiener J et al. | Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo. | 2003 | J. Invest. Dermatol. | pmid:12535206 |
Hiyoshi H et al. | Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. | 2003 | J. Lipid Res. | pmid:12518031 |
Rao CV et al. | Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis. | 2002 | Cancer Detect. Prev. | pmid:12507226 |