2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Muramatsu M et al. | Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18636253 |
Brockmann H and Knobloch G | [A new bacteriochlorophyll from Rhodospirillum rubrum]. | 1972 | Arch Mikrobiol | pmid:4627398 |
Havel CM and Watson JA | Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. | 1992 | Arch. Biochem. Biophys. | pmid:1567218 |
Bai M and Prestwich GD | Inhibition and activation of porcine squalene epoxidase. | 1992 | Arch. Biochem. Biophys. | pmid:1536566 |
Vaidya S et al. | Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A. | 1998 | Arch. Biochem. Biophys. | pmid:9647670 |
Benedict CR et al. | Properties of farnesyl pyrophosphate synthetase of pig liver. | 1965 | Arch. Biochem. Biophys. | pmid:4284635 |
Bentinger M et al. | Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase. | 1998 | Arch. Biochem. Biophys. | pmid:9606952 |
Parmryd I and Dallner G | In vivo prenylation of rat proteins: modification of proteins with penta- and hexaprenyl groups. | 1999 | Arch. Biochem. Biophys. | pmid:10190969 |
Keller RK et al. | Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. | 1996 | Arch. Biochem. Biophys. | pmid:8645011 |
Andres DA et al. | Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. | 1997 | Arch. Biochem. Biophys. | pmid:9328291 |