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Mol Med Today |
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2000 |
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1999 |
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Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells. |
1999 |
Biochimie |
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A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. |
1999 |
Oncogene |
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1999 |
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1999 |
Microbiology (Reading, Engl.) |
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Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
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1999 |
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1999 |
Proc. Natl. Acad. Sci. U.S.A. |
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Oncogene |
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Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs. |
1999 |
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1999 |
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Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction. |
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Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. |
1999 |
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Inhibition of human B cell activation by a novel nonsteroidal anti-inflammatory drug, indometacin famesil. |
1999 |
Immunopharmacology |
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Farnesylthiosalicylic acid inhibits the growth of human Merkel cell carcinoma in SCID mice. |
1999 |
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[Induction of apoptosis by isoprenoids]. |
1999 |
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Activation of the cholesterol pathway and Ras maturation in response to stress. |
1999 |
Oncogene |
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Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
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Novel Ras antagonist blocks human melanoma growth. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
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Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid. |
1999 |
Biochim. Biophys. Acta |
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The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. |
1999 |
J. Hepatol. |
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