2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fioravanti CF and MacInnis AJ | The in vitro effects of farnesol and derivatives on Hymenolepis diminuta. | 1976 | J. Parasitol. | pmid:978365 |
Hanson JR and Nyfeler R | Studies in terpenoid biosynthesis. Part 18. Biosynthesis of culmorin. | 1976 | J. Chem. Soc. Perkin Trans. I | pmid:1034641 |
Ortiz de Montellano PR et al. | Letter: Squalene synthetase. Differentiation between the two substrate binding sites by a substrate analogue. | 1976 | J. Am. Chem. Soc. | pmid:1254859 |
Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
de Montellano PR et al. | Inhibition of squalene synthetase by farnesyl pyrophosphate analogues. | 1977 | J. Med. Chem. | pmid:189031 |
Mackie H and Overton KH | Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes. | 1977 | Eur. J. Biochem. | pmid:198206 |
Ortiz de Montellano PR et al. | Substrate selectivity of squalene synthetase. | 1977 | Biochemistry | pmid:329862 |
Fioravanti CF and MacInnis AJ | The identification and characterization of a prenoid constituent (farnesol) of Hymenolepis diminuta (Cestoda). | 1977 | Comp. Biochem. Physiol., B | pmid:299634 |
Peter MG et al. | [On the incorporation of geraniol and farnesol into cantharidin (author's transl)]. | 1977 | Helv. Chim. Acta | pmid:558966 |
L'Hélias C | [Study on deshydrogenases implicated in control of farnesol and juvenile hormone metabolisms in Pieris brassicae (author's transl)]. | 1977 | Ann. Endocrinol. (Paris) | pmid:612274 |
Peter MG et al. | [Identification of farnesol as an intermediate in the biosynthesis of cantharidin from mevalonolactone]. | 1977 | Helv. Chim. Acta | pmid:599044 |
Micciarelli AS | Effects of farnesyl methyl ether on embryos of Schistocerca Gregaria (Orthoptera). | 1977 | Acta Embryol Exp (Palermo) | pmid:605750 |
Boisvenue RJ et al. | Haemonchus contortus: effects of compounds with juvenile hormone activity on the in vitro development of infective larvae. | 1977 | Exp. Parasitol. | pmid:862711 |
Peter MG et al. | [Incorporation experiments with (3H and 14C) doubly labelled farnesols into cantharidin (author's transl)]. | 1977 | Helv. Chim. Acta | pmid:893117 |
Styczyńska B et al. | [2,3-methylenefarnesenic acid derivatives as juvenile hormone analogs against housefly (Musca domestica L.)]. | 1977 | Wiad Parazytol | pmid:899003 |
King HL and Rilling HC | Avian liver prenyltransferase. The role of metal in substrate binding and the orientation of substrates during catalysis. | 1977 | Biochemistry | pmid:901755 |
Parker TS et al. | Inhibition of liver prenyltransferase by alkyl phosphonates and phosphonophosphates. | 1978 | Biochim. Biophys. Acta | pmid:687653 |
Baba T and Allen CM | Substrate specificity of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. | 1978 | Biochemistry | pmid:728420 |
Tsuchiya E and Fukui S | Binding of rhodotorucine A, a lipopeptidyl mating hormone, to a cells of Rhodosporidium toruloides for induction of sexual differentiation. | 1978 | Biochem. Biophys. Res. Commun. | pmid:743290 |
Bertolino A et al. | Polyisoprenoid amphiphilic compounds as inhibitors of squalene synthesis and other microsomal enzymes. | 1978 | Biochim. Biophys. Acta | pmid:210830 |