2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lerro KA and Prestwich GD | Cloning and sequencing of a cDNA for the hemolymph juvenile hormone binding protein of larval Manduca sexta. | 1990 | J. Biol. Chem. | pmid:2246263 |
Dionigi CP et al. | Effects of farnesol and the off-flavor derivative geosmin on Streptomyces tendae. | 1991 | Appl. Environ. Microbiol. | pmid:1785920 |
Ohguro H et al. | Carboxyl methylation and farnesylation of transducin gamma-subunit synergistically enhance its coupling with metarhodopsin II. | 1991 | EMBO J. | pmid:1935895 |
Fujiyama A et al. | S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation. | 1991 | J. Biol. Chem. | pmid:1917931 |
Keung WM | Human liver alcohol dehydrogenases catalyze the oxidation of the intermediary alcohols of the shunt pathway of mevalonate metabolism. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1993065 |
Bai M and Prestwich GD | Inhibition and activation of porcine squalene epoxidase. | 1992 | Arch. Biochem. Biophys. | pmid:1536566 |
Cox AD et al. | Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. | 1992 | Mol. Cell. Biol. | pmid:1375323 |
Shindo T et al. | A farnesyl arabinoside as an enhancer of glucose transport in rat adipocytes from a soft coral, Sinularia sp. | 1992 | Experientia | pmid:1353460 |
Okazaki S et al. | [A 13-week subcutaneous toxicity study of prednisolone farnesylate (PNF) in rats]. | 1992 | J Toxicol Sci | pmid:1293320 |
Nagashima Y et al. | [A 13-week percutaneous toxicity study of prednisolone farnesylate (PNF) gel in beagle dogs with a recovery period of 5 weeks]. | 1992 | J Toxicol Sci | pmid:1293321 |
Nagashima Y et al. | [A 52-week percutaneous toxicity study of prednisolone farnesylate (PNF) gel in beagle dogs with a recovery period of 8 weeks]. | 1992 | J Toxicol Sci | pmid:1293322 |
Taniguchi H et al. | [Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study by subcutaneous administration of PNF prior to and in the early stages of pregnancy in rats]. | 1992 | J Toxicol Sci | pmid:1293323 |
Taniguchi H et al. | [Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study by subcutaneous administration of PNF during the period of fetal organogenesis in rats]. | 1992 | J Toxicol Sci | pmid:1293324 |
Aso S et al. | [Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--teratogenicity study in rabbits by subcutaneous administration]. | 1992 | J Toxicol Sci | pmid:1293325 |
Taniguchi H et al. | [Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study of subcutaneous administration of PNF during the perinatal and lactation periods in rats]. | 1992 | J Toxicol Sci | pmid:1293326 |
Otsuka M et al. | [Mutagenicity studies of prednisolone farnesylate (PNF)]. | 1992 | J Toxicol Sci | pmid:1293327 |
Uchiyama H et al. | [Effects of prednisolone farnesylate (PNF) gel on skin and ocular mucosa]. | 1992 | J Toxicol Sci | pmid:1293328 |
Okazaki S et al. | [A 13-week dermal toxicity study of prednisolone farnesylate (PNF) gel in rats with a recovery period of 5 weeks]. | 1992 | J Toxicol Sci | pmid:1293330 |
Okazaki S et al. | [A 52-week dermal toxicity study of prednisolone farnesylate (PNF) gel in rats with a recovery period of 8 weeks]. | 1992 | J Toxicol Sci | pmid:1293331 |
Lowe PN et al. | Expression of polyisoprenylated Ras proteins in the insect/baculovirus system. | 1992 | Biochem. Soc. Trans. | pmid:1397645 |