2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Binet L et al. | [Farnesol, psychosedative and spasmolytic drug]. | 1972 Sep-Oct | Therapie | pmid:4405589 |
Madhavan K et al. | Farnesol metabolism in Drosophila melanogaster: ontogeny and tissue distribution of octanol dehydrogenase and aldehyde oxidase. | 1973 | J. Insect Physiol. | pmid:4631837 |
Langman MJ et al. | Treatment of chronic gastric ulcer with carbenoxolone and gefarnate: a comparative trial. | 1973 | Br Med J | pmid:4577839 |
Newman CR and Montgomery DA | A double-blind trial of oral gefarnate in duodenal ulcer. | 1973 | Br J Clin Pract | pmid:4580209 |
Ichiki H and Isoda M | The Mann-Williamson ulcer as a model for testing antiulcer drugs. Results obtained with gefarnate. | 1973 | Arzneimittelforschung | pmid:4740136 |
Qureshi AA et al. | Squalene synthetase. II. Purification and properties of bakers' yeast enzyme. | 1973 | J. Biol. Chem. | pmid:4348552 |
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Derksen A and Cohen P | Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. | 1973 | J. Biol. Chem. | pmid:4355579 |
Shechter I | Biosynthesis of trans-farnesyl triphosphate in Gibberella fujikuroi. | 1973 | Biochim. Biophys. Acta | pmid:4795388 |
Qureshi AA et al. | Biosynthesis of prelycopersene pyrophosphate and lycopersene by squalene synthetase. | 1973 | J. Biol. Chem. | pmid:4144543 |
Davey KG and Sommerville RI | Molting in a parasitic nematode, Phocanema decipiens. VII. The mode of action of the ecdysial hormone. | 1974 | Int. J. Parasitol. | pmid:4853251 |
Tanaka S et al. | Stereoselective epoxidations of acyclic allylic alcohols by transition metal--hydroperoxide reagents. Synthesis of dl-C18 Cecropia juvenile hormone from farnesol. | 1974 | J. Am. Chem. Soc. | pmid:4854400 |
Tobe SS and Pratt GE | The influence of substrate concentrations on the rate of insect juvenile hormone biosynthesis by corpora allata of the desert locust in vitro. | 1974 | Biochem. J. | pmid:4462567 |
Lanzrein B | Influence of a juvenile hormone analogue on vitellogenin synthesis and oögenesis in larvae of Nauphoeta cinerea. | 1974 | J. Insect Physiol. | pmid:4413859 |
Imai K et al. | Letter: Derivation of (plus)- and (minus)-C17-juvenile hormone from its racemic alcohol derivative via fungal metabolism. | 1974 | J. Am. Chem. Soc. | pmid:4414179 |
Shechter I | Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi. | 1974 | Biochim. Biophys. Acta | pmid:4423368 |
Overton KH and Roberts FM | Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. | 1974 | Biochem. J. | pmid:4468823 |
Ellsworth RK and Nowak CA | A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of pumpkin seed protochlorophylls. | 1974 | Anal. Biochem. | pmid:4362215 |
Samuel O et al. | Preparation of (1-3H) polyprenyl pyrophosphates. | 1974 | Biochimie | pmid:4375498 |