2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhang X et al. | Nanomicellar carriers for targeted delivery of anticancer agents. | 2014 | Ther Deliv | pmid:24341817 |
Schmukler E et al. | Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death. | 2014 | Oncotarget | pmid:24368422 |
Matsuzawa T et al. | EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium. | 2014 | J. Invest. Dermatol. | pmid:24384694 |
Sakane C et al. | Inhibition of lysine-specific demethylase 1 by the acyclic diterpenoid geranylgeranoic acid and its derivatives. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24406160 |
pmid:24435839 | ||||
pmid:24444894 | ||||
Lu Y et al. | Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24449897 |
pmid:24584843 | ||||
Chen M et al. | Use of synthetic isoprenoids to target protein prenylation and Rho GTPases in breast cancer invasion. | 2014 | PLoS ONE | pmid:24587105 |
Scheman A et al. | European Directive fragrances in natural products. | 2014 Mar-Apr | Dermatitis | pmid:24603515 |
Ronderos DS et al. | Farnesol-detecting olfactory neurons in Drosophila. | 2014 | J. Neurosci. | pmid:24623773 |
pmid:24691869 | ||||
pmid:24704370 | ||||
Chen Y et al. | Targeted delivery of curcumin to tumors via PEG-derivatized FTS-based micellar system. | 2014 | AAPS J | pmid:24706375 |
pmid:24762323 | ||||
pmid:24848877 | ||||
pmid:24895430 | ||||
Ilayaraja R et al. | Evaluating the binding efficiency of pheromone binding protein with its natural ligand using molecular docking and fluorescence analysis. | 2014 | Sci Rep | pmid:24903953 |
Neeman R et al. | Vitamin D and S-farnesylthiosalicylic acid have a synergistic effect on hepatic stellate cells proliferation. | 2014 | Dig. Dis. Sci. | pmid:24942325 |
Zhang X et al. | PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel. | 2014 | Mol. Pharm. | pmid:24987803 |
Kloog Y et al. | Ras chaperones: new targets for cancer and immunotherapy. | 2013 | Enzymes | pmid:25033809 |
pmid:25043275 | ||||
Zhang X et al. | Reduction-sensitive dual functional nanomicelles for improved delivery of paclitaxel. | 2014 | Bioconjug. Chem. | pmid:25121577 |
Goldshmit Y et al. | Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma. | 2014 | Oncotarget | pmid:25261371 |
pmid:25261400 | ||||
Katragkou A et al. | In vitro interactions between farnesol and fluconazole, amphotericin B or micafungin against Candida albicans biofilms. | 2015 | J. Antimicrob. Chemother. | pmid:25288679 |
Léger T et al. | The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans. | 2015 | Mol. Cell Proteomics | pmid:25348831 |
Okamoto S et al. | Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions. | 2014 | Cell Death Dis | pmid:25393473 |
pmid:25460024 | ||||
pmid:25468257 | ||||
Makovski V et al. | Analysis of gene expression array in TSC2-deficient AML cells reveals IRF7 as a pivotal factor in the Rheb/mTOR pathway. | 2014 | Cell Death Dis | pmid:25476905 |
pmid:25535203 | ||||
De Loof A | The essence of female-male physiological dimorphism: differential Ca2+-homeostasis enabled by the interplay between farnesol-like endogenous sesquiterpenoids and sex-steroids? The Calcigender paradigm. | 2015 | Gen. Comp. Endocrinol. | pmid:25540913 |
pmid:25541558 | ||||
pmid:25542266 | ||||
Rosales A et al. | Synthesis of (±)-aureol by bioinspired rearrangements. | 2015 | J. Org. Chem. | pmid:25591135 |
pmid:25624157 | ||||
Brilhante RS et al. | Histoplasma capsulatum in planktonic and biofilm forms: in vitro susceptibility to amphotericin B, itraconazole and farnesol. | 2015 | J. Med. Microbiol. | pmid:25657300 |
Horev B et al. | pH-activated nanoparticles for controlled topical delivery of farnesol to disrupt oral biofilm virulence. | 2015 | ACS Nano | pmid:25661192 |
pmid:25697480 | ||||
pmid:25735913 | ||||
pmid:25739905 | ||||
Leonhardt I et al. | The fungal quorum-sensing molecule farnesol activates innate immune cells but suppresses cellular adaptive immunity. | 2015 | MBio | pmid:25784697 |
Zhang W et al. | Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission. | 2015 | Pharm. Res. | pmid:25794967 |
Badar T et al. | Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies. | 2015 | Clin Lymphoma Myeloma Leuk | pmid:25795639 |
pmid:25810363 | ||||
pmid:25882299 | ||||
de Salas F et al. | Quorum-Sensing Mechanisms Mediated by Farnesol in Ophiostoma piceae: Effect on Secretion of Sterol Esterase. | 2015 | Appl. Environ. Microbiol. | pmid:25888179 |
pmid:25894100 | ||||
pmid:25935694 |