2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Charette N et al. | Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. | 2010 | Mol. Cancer | pmid:20860815 |
Agassandian M et al. | Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal. | 2012 | Mol. Biol. Cell | pmid:22621903 |
Foster JM et al. | Biosynthesis of isoprenoid compounds in Schistosoma mansoni. | 1993 | Mol. Biochem. Parasitol. | pmid:8264731 |
Kloog Y and Cox AD | RAS inhibitors: potential for cancer therapeutics. | 2000 | Mol Med Today | pmid:11006529 |
Charron G et al. | Alkynyl-farnesol reporters for detection of protein S-prenylation in cells. | 2011 | Mol Biosyst | pmid:21107478 |
Gouveia V et al. | Di- and sesquiterpenoids from Cystoseira genus: structure, intra-molecular transformations and biological activity. | 2013 | Mini Rev Med Chem | pmid:23621654 |
Ortone G and Furno F | [Gefarnate in the therapy of peptic ulcer]. | 1968 | Minerva Med. | pmid:5707471 |
Cesco G | [Geranyl farnesylacetate as a preventive and therapeutic agent in disorders of the digestive system caused by corticoids]. | 1967 Oct-Dec | Minerva Gastroenterol | pmid:5607545 |
Da Grada CT et al. | [Endoscopic study of clinical trials of geranyl farnesylacetate]. | 1967 Oct-Dec | Minerva Gastroenterol | pmid:5607546 |