2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cao YY et al. | cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesol. | 2005 | Antimicrob. Agents Chemother. | pmid:15673737 |
Blum R et al. | Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. | 2005 | Cancer Res. | pmid:15705901 |
Hubálek F et al. | Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. | 2005 | J. Biol. Chem. | pmid:15710600 |
Laffey SF and Butler G | Phenotype switching affects biofilm formation by Candida parapsilosis. | 2005 | Microbiology (Reading, Engl.) | pmid:15817776 |
Horn TL et al. | Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol. | 2005 | Chem. Biol. Interact. | pmid:15840382 |
Frosch PJ et al. | Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. | 2005 | Contact Derm. | pmid:15859993 |
Frosch PJ et al. | Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products. | 2005 | Contact Derm. | pmid:15859994 |
Katsuyama M et al. | A novel method to control the balance of skin microflora. Part 1. Attack on biofilm of Staphylococcus aureus without antibiotics. | 2005 | J. Dermatol. Sci. | pmid:15927813 |
Katsuyama M et al. | A novel method to control the balance of skin microflora Part 2. A study to assess the effect of a cream containing farnesol and xylitol on atopic dry skin. | 2005 | J. Dermatol. Sci. | pmid:15927814 |
Yue W et al. | Farnesylthiosalicylic acid blocks mammalian target of rapamycin signaling in breast cancer cells. | 2005 | Int. J. Cancer | pmid:15957161 |