2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dinamarco TM et al. | Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans. | 2011 | Biochem. Soc. Trans. | pmid:21936849 |
Lowe PN et al. | Expression of polyisoprenylated Ras proteins in the insect/baculovirus system. | 1992 | Biochem. Soc. Trans. | pmid:1397645 |
Nigg EA et al. | Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. | 1992 | Biochem. Soc. Trans. | pmid:1397650 |
Haklai R et al. | Dislodgment and accelerated degradation of Ras. | 1998 | Biochemistry | pmid:9477957 |
Baba T and Allen CM | Substrate specificity of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. | 1978 | Biochemistry | pmid:728420 |
Nishimori R et al. | Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum. | 2011 | Biochemistry | pmid:21846125 |
Clausen VA et al. | Stereochemical analysis of the reaction catalyzed by human protein geranylgeranyl transferase. | 2001 | Biochemistry | pmid:11300771 |
Murataliev MB et al. | Chimeragenesis of the fatty acid binding site of cytochrome P450BM3. Replacement of residues 73-84 with the homologous residues from the insect cytochrome P450 CYP4C7. | 2004 | Biochemistry | pmid:14967018 |
Koyama T et al. | Identification of significant residues in the substrate binding site of Bacillus stearothermophilus farnesyl diphosphate synthase. | 1996 | Biochemistry | pmid:8755734 |
Gilbert BA et al. | Farnesyl thiotriazole, a potent neutrophil agonist and structurally novel activator of protein kinase C. | 1995 | Biochemistry | pmid:7696255 |