2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mor A et al. | Celecoxib enhances the anti-inflammatory effects of farnesylthiosalicylic acid on T cells independent of prostaglandin E(2) production. | 2012 | Inflammation | pmid:22688643 |
Nasr N et al. | HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. | 2012 | Blood | pmid:22677126 |
Cordeiro Rde A et al. | Farnesol inhibits in vitro growth of the Cryptococcus neoformans species complex with no significant changes in virulence-related exoenzymes. | 2012 | Vet. Microbiol. | pmid:22580194 |
Cerca N et al. | Confocal laser scanning microscopy analysis of S. epidermidis biofilms exposed to farnesol, vancomycin and rifampicin. | 2012 | BMC Res Notes | pmid:22591918 |
Costa CB et al. | Farnesyltransferase inhibitors: molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition. | 2012 | Anticancer Res. | pmid:22399601 |
Jamalian A et al. | Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens. | 2012 | J Mycol Med | pmid:23518164 |
Shin KO et al. | Terpene alcohols inhibit de novo sphingolipid biosynthesis. | 2012 | Planta Med. | pmid:22274813 |
Yu LH et al. | Possible inhibitory molecular mechanism of farnesol on the development of fluconazole resistance in Candida albicans biofilm. | 2012 | Antimicrob. Agents Chemother. | pmid:22106223 |
Deveau A and Hogan DA | Linking quorum sensing regulation and biofilm formation by Candida albicans. | 2011 | Methods Mol. Biol. | pmid:21031315 |
de Castro Pimentel Figueiredo B et al. | The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death. | 2011 | Eukaryotic Cell | pmid:21131437 |
Gomes F et al. | Farnesol as antibiotics adjuvant in Staphylococcus epidermidis control in vitro. | 2011 | Am. J. Med. Sci. | pmid:21107231 |
Shareck J and Belhumeur P | Modulation of morphogenesis in Candida albicans by various small molecules. | 2011 | Eukaryotic Cell | pmid:21642508 |
Yoo S et al. | Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. | 2011 | Caries Res. | pmid:21720161 |
Zhang L et al. | Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. | 2011 | PLoS ONE | pmid:22174935 |
Biran A et al. | Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy. | 2011 | Int. J. Cancer | pmid:20473860 |
Goto T et al. | Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21862726 |
Fitzpatrick AH et al. | Roles for farnesol and ABA in Arabidopsis flower development. | 2011 | Plant Signal Behav | pmid:21758018 |
Mor A et al. | Ras inhibition induces insulin sensitivity and glucose uptake. | 2011 | PLoS ONE | pmid:21738773 |
Sharma M and Prasad R | The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. | 2011 | Antimicrob. Agents Chemother. | pmid:21768514 |
Nishimori R et al. | Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum. | 2011 | Biochemistry | pmid:21846125 |