2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cho T et al. | [Farnesol as a quorum-sensing molecule in Candida albicans]. | 2008 | Nihon Ishinkin Gakkai Zasshi | pmid:19001754 |
Cho T et al. | Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. | 2007 | Nihon Ishinkin Gakkai Zasshi | pmid:17975531 |
Kogo Y and kato J | [Malignant tumor and apoptosis]. | 1997 | Nippon Naika Gakkai Zasshi | pmid:9410963 |
Cho T and Aoyama T | [Quorum sensing in fungal pathogenesis]. | 2008 | Nippon Rinsho | pmid:19069092 |
Jones S et al. | β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells. | 2013 | Nutr Cancer | pmid:23659452 |
Willumsen BM et al. | Novel determinants of H-Ras plasma membrane localization and transformation. | 1996 | Oncogene | pmid:8934536 |
Vogt A et al. | Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts. | 1996 | Oncogene | pmid:8934546 |
Hanker AB et al. | Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling. | 2010 | Oncogene | pmid:19838215 |
Ghosh PM et al. | Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. | 1999 | Oncogene | pmid:10435593 |
Shack S et al. | Activation of the cholesterol pathway and Ras maturation in response to stress. | 1999 | Oncogene | pmid:10557091 |