2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.
To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
McPherson RA et al. | The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro. | 2004 | Prostate | pmid:14968433 |
Banfi C et al. | Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme. | 2009 | Proteomics | pmid:19253276 |
Blum R et al. | Inhibitors of chronically active ras: potential for treatment of human malignancies. | 2008 | Recent Pat Anticancer Drug Discov | pmid:18289122 |
Jahangir T et al. | Alleviation of free radical mediated oxidative and genotoxic effects of cadmium by farnesol in Swiss albino mice. | 2005 | Redox Rep. | pmid:16438802 |
Lima JP et al. | [Gefarnate (DA-688) in the treatment of peptic ulcer; immediate results]. | 1966 | Rev Bras Med | pmid:5940586 |
Mincis M | [Clinical study of the effect of geranyl of farnesylacetate combined with nafiver in peptic ulcer patients]. | 1968 | Rev Bras Med | pmid:5724217 |
Pastor Franco A | [Clinicobiological evolution of duodenal ulcer treated with gefarnate]. | 1966 | Rev Clin Esp | pmid:4286000 |
Marcos Becerro JF and Rodriguez Gorostiza FJ | [The effect of farnesyl geranyl acetate on duodenal ulcer]. | 1968 | Rev Esp Enferm Apar Dig | pmid:5670667 |
Akisue G | [Secretion of Myroxylon peruiforum L.f. 3. Physical and chemical characterization of essential oil from balsam and qualitative analysis of various componets]. | 1972 Jul-Dec | Rev Farm Bioquim Univ Sao Paulo | pmid:4664898 |