2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

Cross Reference

Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Osteosarcoma D012516 50 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Arteriosclerosis D001161 86 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fibrosis D005355 23 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Dermatomycoses D003881 17 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Meningioma D008579 11 associated lipids
Neuritis, Autoimmune, Experimental D009444 4 associated lipids
Glioblastoma D005909 27 associated lipids
Nephritis D009393 19 associated lipids
HIV Infections D015658 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Neurilemmoma D009442 10 associated lipids
Head Injuries, Closed D016489 5 associated lipids
Insulin Resistance D007333 99 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Neuralgia D009437 28 associated lipids
Lung Injury D055370 14 associated lipids
Neoplasms, Glandular and Epithelial D009375 12 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Candidiasis, Invasive D058365 2 associated lipids
Anisakiasis D017129 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

Download all related citations
Per page 10 20 50 100 | Total 950
Authors Title Published Journal PubMed Link
Matsuzawa T et al. EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium. 2014 J. Invest. Dermatol. pmid:24384694
Ronderos DS et al. Farnesol-detecting olfactory neurons in Drosophila. 2014 J. Neurosci. pmid:24623773
Lu Y et al. Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24449897
Sakane C et al. Inhibition of lysine-specific demethylase 1 by the acyclic diterpenoid geranylgeranoic acid and its derivatives. 2014 Biochem. Biophys. Res. Commun. pmid:24406160
Sabra A et al. Host-pathogen interaction and signaling molecule secretion are modified in the dpp3 knockout mutant of Candida lusitaniae. 2014 Infect. Immun. pmid:24191303
Aizman E et al. Therapeutic effect of farnesylthiosalicylic acid on adjuvant-induced arthritis through suppressed release of inflammatory cytokines. 2014 Clin. Exp. Immunol. pmid:24215151
Neeman R et al. Vitamin D and S-farnesylthiosalicylic acid have a synergistic effect on hepatic stellate cells proliferation. 2014 Dig. Dis. Sci. pmid:24942325
Zhang X et al. Nanomicellar carriers for targeted delivery of anticancer agents. 2014 Ther Deliv pmid:24341817
Makovski V et al. Analysis of gene expression array in TSC2-deficient AML cells reveals IRF7 as a pivotal factor in the Rheb/mTOR pathway. 2014 Cell Death Dis pmid:25476905
Okamoto S et al. Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions. 2014 Cell Death Dis pmid:25393473