2E,6E-farnesol

2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids.

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Introduction

To understand associated biological information of 2E,6E-farnesol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2E,6E-farnesol?

2E,6E-farnesol is suspected in Granulomatous Disease, Chronic, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2E,6E-farnesol

MeSH term MeSH ID Detail
Lung Injury D055370 14 associated lipids
Dermatomycoses D003881 17 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Nephritis D009393 19 associated lipids
HIV Infections D015658 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Fibrosis D005355 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Glioblastoma D005909 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 2E,6E-farnesol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2E,6E-farnesol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2E,6E-farnesol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2E,6E-farnesol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2E,6E-farnesol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2E,6E-farnesol

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Authors Title Published Journal PubMed Link
Okazaki S et al. [A 13-week dermal toxicity study of prednisolone farnesylate (PNF) gel in rats with a recovery period of 5 weeks]. 1992 J Toxicol Sci pmid:1293330
Okazaki S et al. [A 52-week dermal toxicity study of prednisolone farnesylate (PNF) gel in rats with a recovery period of 8 weeks]. 1992 J Toxicol Sci pmid:1293331
Dietrich A et al. Studies on G-protein alpha.betagamma heterotrimer formation reveal a putative S-prenyl-binding site in the alpha subunit. 2003 Biochem. J. pmid:12952523
Shchepin R et al. Quorum sensing in Candida albicans: probing farnesol's mode of action with 40 natural and synthetic farnesol analogs. 2003 Chem. Biol. pmid:12954333
Giricz Z et al. Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis. 2003 Basic Res. Cardiol. pmid:12955403
Shindo T et al. A farnesyl arabinoside as an enhancer of glucose transport in rat adipocytes from a soft coral, Sinularia sp. 1992 Experientia pmid:1353460
Cox AD et al. Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. 1992 Mol. Cell. Biol. pmid:1375323
Lowe PN et al. Expression of polyisoprenylated Ras proteins in the insect/baculovirus system. 1992 Biochem. Soc. Trans. pmid:1397645
Nigg EA et al. Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. 1992 Biochem. Soc. Trans. pmid:1397650
Akopyan TN et al. Cleavage of farnesylated COOH-terminal heptapeptide of mouse N-ras by brain microsomal membranes: evidence for a carboxypeptidase which specifically removes the COOH-terminal methionine. 1992 Biochem. Biophys. Res. Commun. pmid:1417809