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Anticancer effects of zoledronic acid against human osteosarcoma cells. |
2006 |
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Talking to themselves: autoregulation and quorum sensing in fungi. |
2006 |
Eukaryotic Cell |
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Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. |
2006 |
Am. J. Nephrol. |
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Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog. |
2006 |
Arch. Biochem. Biophys. |
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Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells. |
2006 |
Anticancer Drugs |
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3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium. |
2006 |
J Ethnopharmacol |
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Farnesylthiosalicylic acid induces caspase activation and apoptosis in glioblastoma cells. |
2006 |
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Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase. |
2006 |
Carcinogenesis |
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2006 |
Mol. Reprod. Dev. |
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The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1. |
2006 |
Clin. Cancer Res. |
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In vitro synergistic effect of farnesol and human gingival cells against Candida albicans. |
2006 |
Yeast |
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Effect of farnesol on Staphylococcus aureus biofilm formation and antimicrobial susceptibility. |
2006 |
Antimicrob. Agents Chemother. |
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Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke. |
2006 |
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A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. |
2006 |
Appl. Biochem. Biotechnol. |
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Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro. |
2006 |
Biomaterials |
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E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition. |
2006 |
Int. J. Cancer |
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Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA. |
2006 |
Genetics |
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Effect of farnesol on Candida dubliniensis biofilm formation and fluconazole resistance. |
2006 |
FEMS Yeast Res. |
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Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design. |
2006 |
Neurology |
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Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. |
2006 |
Eukaryotic Cell |
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Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis. |
2006 |
Mol. Cancer Ther. |
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The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. |
2006 |
FEBS J. |
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Use of the Porcine Intestinal Epithelium (PIE)-Assay to analyze early stages of colonization by the human fungal pathogen Candida albicans. |
2006 |
J. Basic Microbiol. |
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Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe. |
2006 |
J. Biochem. |
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Farnesol induces thyroid hormone receptor (THR) beta1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells. |
2006 |
Biochem. Biophys. Res. Commun. |
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Efficacy of an alcohol-based healthcare hand rub containing synergistic combination of farnesol and benzethonium chloride. |
2006 |
Int J Hyg Environ Health |
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Quorum sensing in dimorphic fungi: farnesol and beyond. |
2006 |
Appl. Environ. Microbiol. |
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Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens. |
2006 |
Genome |
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Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells. |
2006 Jan-Feb |
Int. J. Gynecol. Cancer |
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Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. |
2007 |
J. Antimicrob. Chemother. |
pmid:17242033
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The effect of terpene concentrations on the skin penetration of diclofenac sodium. |
2007 |
Int J Pharm |
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The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways. |
2007 |
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Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. |
2007 |
Nihon Ishinkin Gakkai Zasshi |
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2007 |
Lett. Appl. Microbiol. |
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Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans. |
2007 |
Infect. Immun. |
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Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. |
2007 |
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Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). |
2007 |
Mol. Cancer Ther. |
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Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model. |
2007 |
Infect. Immun. |
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Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue. |
2007 |
Yeast |
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Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. |
2007 |
Plant J. |
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Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid). |
2007 |
Cancer Res. |
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Transcriptional response of Candida parapsilosis following exposure to farnesol. |
2007 |
Antimicrob. Agents Chemother. |
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Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. |
2007 |
Mol. Microbiol. |
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In vivo and in vitro anaerobic mating in Candida albicans. |
2007 |
Eukaryotic Cell |
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Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. |
2007 |
Infect Control Hosp Epidemiol |
pmid:17265401
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Zhang L and Hill RP |
Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. |
2007 |
Cancer Res. |
pmid:17699784
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Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. |
2007 |
Cancer Res. |
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Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. |
2007 |
J Chromatogr A |
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Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. |
2007 |
J. Neurotrauma |
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Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro. |
2007 |
Planta Med. |
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Lombardi L et al. |
Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator. |
2007 |
Genetics |
pmid:17237512
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Cheng AX et al. |
The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. |
2007 |
Phytochemistry |
pmid:17524436
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Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17138864
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A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway. |
2007 |
J. Biol. Chem. |
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Cetin A et al. |
Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. |
2007 |
Pharmacology |
pmid:17135774
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Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. |
2007 |
J. Thromb. Haemost. |
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Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. |
2007 Aug-Sep |
J. Steroid Biochem. Mol. Biol. |
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3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol. |
2007 Mar-Apr |
J Environ Sci Health B |
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Zoledronate inhibits alphavbeta3 and alphavbeta5 integrin cell surface expression in endothelial cells. |
2007 Mar-Apr |
Endothelium |
pmid:17497369
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Duncan RE and Archer MC |
Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. |
2008 |
Lipids |
pmid:18509688
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Zhao M et al. |
Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. |
2008 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:18534927
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Mor A et al. |
N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. |
2008 |
Eur. J. Immunol. |
pmid:18461565
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Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. |
2008 |
Mol. Microbiol. |
pmid:18681941
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Kotti T et al. |
Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18685105
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Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma. |
2008 |
Cancer Invest. |
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Geraldo IM et al. |
Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents. |
2008 |
Infect Control Hosp Epidemiol |
pmid:18616390
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Muramatsu M et al. |
Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. |
2008 |
Appl. Microbiol. Biotechnol. |
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Fragrance material review on farnesol. |
2008 |
Food Chem. Toxicol. |
pmid:18640198
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Jahangir T and Sultana S |
Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model. |
2008 |
J Enzyme Inhib Med Chem |
pmid:18618320
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Competition between native liver and graft in auxiliary liver transplantation in a rat model. |
2008 |
Transplant. Proc. |
pmid:18555091
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Hisajima T et al. |
Protective effects of farnesol against oral candidiasis in mice. |
2008 |
Microbiol. Immunol. |
pmid:18667031
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Scheper MA et al. |
Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells. |
2008 |
Neoplasia |
pmid:18714396
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Muramatsu M et al. |
Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols. |
2008 |
J. Biosci. Bioeng. |
pmid:18930003
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Qamar W and Sultana S |
Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. |
2008 |
Chem. Biol. Interact. |
pmid:18793622
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Peleg AY et al. |
Prokaryote-eukaryote interactions identified by using Caenorhabditis elegans. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18794525
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Cho T and Aoyama T |
[Quorum sensing in fungal pathogenesis]. |
2008 |
Nippon Rinsho |
pmid:19069092
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Goldberg L et al. |
Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats. |
2008 |
Mol. Cancer Ther. |
pmid:19001442
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Cho T et al. |
[Farnesol as a quorum-sensing molecule in Candida albicans]. |
2008 |
Nihon Ishinkin Gakkai Zasshi |
pmid:19001754
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Abbasnezhad H et al. |
Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. |
2008 |
Colloids Surf B Biointerfaces |
pmid:17997081
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Koo H |
Strategies to enhance the biological effects of fluoride on dental biofilms. |
2008 |
Adv. Dent. Res. |
pmid:18694872
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Haklai R et al. |
Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. |
2008 |
Cancer Chemother. Pharmacol. |
pmid:17909812
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Zvibel I et al. |
The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. |
2008 |
Dig. Dis. Sci. |
pmid:17934818
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Journe F et al. |
Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. |
2008 |
Breast Cancer Res. Treat. |
pmid:17333335
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da Silva Morais A et al. |
Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. |
2008 |
Clin. Sci. |
pmid:17678500
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Togashi N et al. |
Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. |
2008 |
Molecules |
pmid:19078849
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Shchepin R et al. |
Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. |
2008 |
Bioorg. Med. Chem. |
pmid:18037299
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Semighini CP et al. |
Inhibition of Fusarium graminearum growth and development by farnesol. |
2008 |
FEMS Microbiol. Lett. |
pmid:18201191
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Golczak M et al. |
Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. |
2008 |
J. Biol. Chem. |
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Activation of TRPA1 by farnesyl thiosalicylic acid. |
2008 |
Mol. Pharmacol. |
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Shimomura K et al. |
Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. |
2008 |
J. Chem. Ecol. |
pmid:18351422
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Secretion of E,E-farnesol and biofilm formation in eight different Candida species. |
2008 |
Antimicrob. Agents Chemother. |
pmid:18332168
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Teshima K and Kondo T |
Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. |
2008 |
J Pharm Biomed Anal |
pmid:18313250
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Tsangarakis C et al. |
Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. |
2008 |
J. Org. Chem. |
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Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. |
2008 |
J. Med. Microbiol. |
pmid:18436588
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Joo JH and Jetten AM |
NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. |
2008 |
J. Biol. Chem. |
pmid:18424438
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Kebaara BW et al. |
Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. |
2008 |
Eukaryotic Cell |
pmid:18424510
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Rotblat B et al. |
The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. |
2008 |
Meth. Enzymol. |
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Lorek J et al. |
Influence of farnesol on the morphogenesis of Aspergillus niger. |
2008 |
J. Basic Microbiol. |
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Marcuzzi A et al. |
Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. |
2008 |
Pediatr. Res. |
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Chen CK et al. |
The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. |
2008 |
J. Biol. Inorg. Chem. |
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